Search Results - "Sharman, P."
-
1
Bruton Tyrosine Kinase Inhibitor Ibrutinib (PCI-32765) Has Significant Activity in Patients With Relapsed/Refractory B-Cell Malignancies
Published in Journal of clinical oncology (01-01-2013)“…Survival and progression of mature B-cell malignancies depend on signals from the B-cell antigen receptor, and Bruton tyrosine kinase (BTK) is a critical…”
Get full text
Journal Article -
2
Survival Trends and Syndromic Esophageal Atresia
Published in Pediatrics (Evanston) (01-05-2021)“…Presence of a syndrome (or association) is predictive of poor survival in esophageal atresia (EA). However, most reports rely on historical patient outcomes,…”
Get full text
Journal Article -
3
Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lymphoma
Published in The New England journal of medicine (27-01-2022)“…The treatment outcome for diffuse large B-cell lymphoma has not been improved in nearly 20 years. However, the replacement of vincristine in R-CHOP with…”
Get full text
Journal Article -
4
Medical and surgical management of pediatric perianal crohn's disease: A systematic review
Published in Journal of pediatric surgery (01-12-2019)“…The timely management of pediatric Crohn's disease (CD), and specifically perianal CD, is important owing to the possible adverse effects on growth,…”
Get full text
Journal Article -
5
Idelalisib or placebo in combination with bendamustine and rituximab in patients with relapsed or refractory chronic lymphocytic leukaemia: interim results from a phase 3, randomised, double-blind, placebo-controlled trial
Published in The lancet oncology (01-03-2017)“…Summary Background Bendamustine plus rituximab is a standard of care for the management of patients with relapsed or refractory chronic lymphocytic leukaemia…”
Get full text
Journal Article -
6
Phase II study of acalabrutinib in ibrutinib-intolerant patients with relapsed/refractory chronic lymphocytic leukemia
Published in Haematologica (Roma) (01-09-2021)“…B-cell receptor signalling inhibition by targeting Bruton tyrosine kinase (BTK) is effective in treating chronic lymphocytic leukemia (CLL). The BTK inhibitor…”
Get full text
Journal Article -
7
Surgical management of perianal abscess in neonates and infants
Published in ANZ journal of surgery (01-06-2020)“…Background The optimal management of perianal abscess in neonates and infants remains unclear, including the need for laying open of the fistula and the role…”
Get full text
Journal Article -
8
Current surgical practice in pediatric ulcerative colitis: A systematic review
Published in Journal of pediatric surgery (01-07-2019)“…Surgical management of adult ulcerative colitis (UC) is well-studied, but not readily applicable to children. Restorative proctocolectomy with ileal pouch-anal…”
Get full text
Journal Article -
9
Esophago‐gastric junction findings on high resolution impedance manometry in children with esophageal atresia
Published in Journal of pediatric gastroenterology and nutrition (01-06-2024)“…Objectives Using high resolution impedance manometry (HRIM), this study characterized the esophago‐gastric junction (EGJ) dynamics in children with esophageal…”
Get full text
Journal Article -
10
Phase 2 study of frontline brentuximab vedotin monotherapy in Hodgkin lymphoma patients aged 60 years and older
Published in Blood (24-12-2015)“…Outcomes in older patients with Hodgkin lymphoma (HL) tend to be poor following conventional chemotherapy regimens. Treatment-related toxicity is significant…”
Get full text
Journal Article -
11
H-type congenital tracheoesophageal fistula: Insights from 70 years of The Royal Children's Hospital experience
Published in Journal of pediatric surgery (01-04-2021)“…The long-term outcomes of H-type tracheoesophageal fistula (TOF), an uncommon variant of esophageal atresia/tracheoesophageal fistula (OA/TOF), are rarely…”
Get full text
Journal Article -
12
Quality of life assessment in esophageal atresia patients: a systematic review focusing on long-gap esophageal atresia
Published in Journal of pediatric surgery (01-12-2019)“…Children born with esophageal atresia (EA) have inherent abnormalities in esophageal motility which may impact upon patient and family Quality of Life (QoL)…”
Get full text
Journal Article -
13
Distinguishing Lyme from septic knee monoarthritis in Lyme disease-endemic areas
Published in Pediatrics (Evanston) (01-03-2013)“…Because Lyme and septic arthritis may present similarly, we sought to identify children with knee monoarthritis at low risk for septic arthritis who may not…”
Get full text
Journal Article -
14
The burden of esophageal dilatations following repair of esophageal atresia
Published in Journal of pediatric surgery (01-11-2020)“…To describe the burden of esophageal dilatations in patients following esophageal atresia (EA) repair. A retrospective review was performed at The Royal…”
Get full text
Journal Article -
15
Cost-Effectiveness of Thrombolysis Within 4.5 Hours of Acute Ischemic Stroke: Experience From Australian Stroke Center
Published in Stroke (1970) (01-08-2013)“…BACKGROUND AND PURPOSE—Previous economic studies outside Australia have demonstrated that patients treated with tissue-type plasminogen activator (tPA) within…”
Get full text
Journal Article -
16
Quality of Life Outcomes in Primary Caregivers of Children with Esophageal Atresia
Published in The Journal of pediatrics (01-11-2021)“…To investigate the quality of life (QoL) impact on primary caregivers of children with esophageal atresia. We used a prospective cohort study design, inviting…”
Get full text
Journal Article -
17
Esophageal morbidity in patients following repair of esophageal atresia: A systematic review
Published in Journal of pediatric surgery (01-09-2021)“…Esophageal atresia (EA) is a life-threatening congenital condition, affecting one in 2600 newborns. Morbidity remains high, with many patients experiencing…”
Get full text
Journal Article -
18
A clinical practice comparison of patients with chronic lymphocytic leukemia with and without deletion 17p receiving first-line treatment with ibrutinib
Published in Haematologica (Roma) (01-11-2022)“…Among patients with chronic lymphocytic leukemia (CLL) with deletion 17p (del[17p]), evidence from clinical trials for the effectiveness of single-agent…”
Get full text
Journal Article -
19
Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial
Published in The lancet oncology (01-01-2014)“…Summary Background Chemoimmunotherapy has led to improved numbers of patients achieving disease response, and longer overall survival in young patients with…”
Get full text
Journal Article -
20
Predictors of Mortality after Primary Discharge from Hospital in Patients with Esophageal Atresia
Published in The Journal of pediatrics (01-04-2020)“…To describe esophageal atresia mortality rates and their associations in our cohort. Patients with esophageal atresia, managed at The Royal Children's…”
Get full text
Journal Article