Search Results - "Sharma, Michael"

Cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine signaling by Mahapatra, Samiksha, Sharma, Michael V R, Brownson, Breanna, Gallicano, Vaughn E, Gallicano, G Ian

“…Myocardial fibrosis (MF), a common event that develops after myocardial infarction, initially is a reparative process, but eventually leads to heart failure…”
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Reversing Cardiac Hypertrophy at the Source Using a Cardiac Targeting Peptide Linked to miRNA106a: Targeting Genes That Cause Cardiac Hypertrophy by Gallicano, G Ian, Fu, Jiayu, Mahapatra, Samiksha, Sharma, Michael V R, Dillon, Conor, Deng, Claire, Zahid, Maliha

“…Causes and treatments for heart failure (HF) have been investigated for over a century culminating in data that have led to numerous pharmacological and…”
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Wait times among patients with symptomatic carotid artery stenosis requiring carotid endarterectomy for stroke prevention by Jetty, Prasad, MD, MSc, FRCSC, Husereau, Don, BSc, MSc, Kubelik, Dalibor, MD, FRCSC, Nagpal, Sudhir, MD, FRCSC, Brandys, Tim, MD, FRCSC, Hajjar, George, MD, FRCSC, Hill, Andrew, MD, FRCSC, Sharma, Michael, MD, FRCPC

“…Background Current Canadian and international guidelines suggest patients with transient ischemic attack (TIA) or nondisabling stroke and ipsilateral internal…”
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Corbevax Vaccine Side Effects in Children of Age Group 12–14 Years: A Prospective Observational Study by Pushkar, Kumar, Bobdey, Saurabh, Kotoki, Rituraj, Koundinya, Kunal, Michael, Priyanka Sharma, Kaushik, S. K.

“…Introduction: Corbevax was introduced by the Government of India in March 2022 for the vaccination of children between 12 and 14 years, however, there is a…”
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National Survey of Canadian Neurologists' Current Practice for Transient Ischemic Attack and the Need for a Clinical Decision Rule by PERRY, Jeffrey J, MANSOUR, Marlène, SHARMA, Michael, SYMINGTON, Cheryl, BREHAUT, Jamie, TALJAARD, Monica, STIELL, Ian G

“…Four percent to 10% of patients with transient ischemic attack (TIA) have a stroke or die within 1 week of their diagnosis. This national survey examined…”
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Satisfaction With Palliative Care After Stroke: A Prospective Cohort Study by BLACQUIERE, Dylan, BHIMJI, Khadija, MEGGISON, Hilary, SINCLAIR, John, SHARMA, Michael

“…The determinants of satisfaction for families of acute stroke patients receiving palliative care have not been extensively studied. We surveyed families to…”
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Expression of oncogenic HRAS G12V causes defects in control of cell size in NIH 3T3 cells by DeWitt, Jerry T, Sharma, Michael V, Kellogg, Douglas R

“…Severe defects in control of cell size are closely associated with cancer. However, the mechanisms that drive cell size defects in cancer remain unknown and it…”
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Dabigatran versus rivaroxaban for the prevention of stroke and systemic embolism in atrial fibrillation in Canada. Comparative efficacy and cost-effectiveness by Kansal, Anuraag R, Sharma, Michael, Bradley-Kennedy, Carole, Clemens, Andreas, Monz, Brigitta U, Peng, Siyang, Roskell, Neil, Sorensen, Sonja V

“…Canadian patients with atrial fibrillation (AF) in whom anticoagulation is appropriate have two new choices for anticoagulation for prevention of stroke and…”
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Delays in carotid endarterectomy: the process is the problem by Blacquiere, Dylan, Sharma, Michael, Jetty, Prasad

“…Current recommendations for carotid endarterectomy (CEA) for symptomatic carotid stenosis state benefit is greatest when performed within two weeks of…”
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Abstract 1723: Novel drug candidates CEP1430 and CEP1507 against cancer stem cells and circulating tumor cells in advanced stage pancreatic cancer by Sharma, Cristian, Narayanan, Padmini, Sharma, Michael, Rodriguez, Robert, Navel, Miriam, Stanton, Donna, Amezcua, Natalee, Sharma, Shaleekha, Amiri, Mandana, Jani, Jitesh, Sharma, Sherven, Sharma, Jay P.

“…Despite improvements in treatment modalities, pancreatic cancer remains the fourth leading cause of cancer mortality in the US. The 5-year survival rate is…”
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Abstract 3889: Novel drug candidates cep1430 and cep1507 for targeting pancreatic patient-derived xenograft cancer stem cell and circulating tumor cell models by Sharma, Michael, Jain, Maulik, Sharma, Cristian, Amezcua, Karina, Amezcua, Natalee, Hasson, Reed, Navel, Miriam, Stanton, Donna, Narayan, Satya, Kramberger, Karl, Punzalan, Rubio, Jani, Jitesh, Foster, Douglas, Sharma, Jay P.

“…Pancreatic cancer is the fourth leading cause of cancer mortality in the US, despite significant improvements in diagnostic imaging and operative mortality…”
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Canadian Stroke Best Practice Recommendations: Acute Inpatient Stroke Care Guidelines, Update 2015 by Casaubon, Leanne K, Boulanger, Jean-Martin, Glasser, Ev, Blacquiere, Dylan, Boucher, Scott, Brown, Kyla, Goddard, Tom, Gordon, Jacqueline, Horton, Myles, Lalonde, Jeffrey, LaRivière, Christian, Lavoie, Pascale, Leslie, Paul, McNeill, Jeanne, Menon, Bijoy K, Moses, Brian, Penn, Melanie, Perry, Jeff, Snieder, Elizabeth, Tymianski, Dawn, Foley, Norine, Smith, Eric E, Gubitz, Gord, Hill, Michael D, Lindsay, Patrice

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Abstract WP120: Granuloctye-Colony Stimulating Factor in Ischemic Stroke Trial (GIST): A Pilot Study by Sharma, Michael, Gladstone, David, Black, Sandra, Blacquiere, Dylan, Hogan, Matthew, Stotts, Grant, Walker, Lisa, Atkins, Harry

“…Abstract only Introduction: Granulocyte-colony stimulating factor (G-CSF) is upregulated in models of cerebral ischemia. This may promote hematopoietic stem…”
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Abstract 3907: Human pancreatic cancer stem cells utilized to generate an in-vivo mouse/rat model system for screening potential drug candidates for treatment of pancreatic cancer patients by Sharma, Cristian, Cleary, Patrick, Gomez, Esteban, Satish, Shruthi, Sharma, Michael, Perez, Michael, Amecuza, Natalee, Jani, Jitesh, Punzalan, Rubio, Sharma, Jay P.

“…Cancer stem cells (CSCs) are critical for engraftment and long-term growth of many tumors, including pancreatic cancer. The Cancer Stem cells are less…”
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Abstract 4225: A novel pharmacological inhibitor CEP1430 for human pancreatic cancer stem cells by Jani, Jitesh, Amiri, Mandana, Sharma, Cristian, Harris, Joshua, Satish, Shruthi, Sharma, Michael, Rodriguez, Robert, Navel, Miriam, Amezcua, Natalee, Sharma, Shaleekha, Sharma, Arun, Desai, Dhimant, Amin, Shantu, Narayan, Satya, Punzalan, Rubio, Sharma, Jay P.

“…Pancreatic cancer is one of the most devastating human malignancies with an estimate yearly death of 280,000 and an overall median 5-year survival rate of less…”
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45-years between skin lesions and CNS symptoms in a patient with scleroderma by Wasserman, Jason K, Glikstein, Rafael, Sharma, Michael

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Abstract 2712: ISC-4, a novel inhibitor of hedgehog-Gli signaling, inhibits growth of CSC and CTC of melanoma patients by Sharma, Arun K., Jani, Jitesh, Sharma, Cristian, Cleary, Patrick, Sharma, Michael, Satish, Shruthi, Gomez, Esteban, Prez, Michael, Amezcua, Natalee, Navel, Mariam, Karelia, Deepkamal N., Desai, Dhimant, Amin, Shantu, Sharma, Jay

“…Melanoma is one of the most aggressive cancers, and its incidence and mortality rate are on rise since no treatment options are available for metastatic…”
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Abstract 5545: Optimal drug concentration screening and evaluation in cancer stem cells & 3D tumor stem cell cultures drug response assays in association with clinical efficacy for pancreatic cancer stem cell by Clery, John P., Gomez, Esteban, Sharma, Michael, khemani, Aabha, Sharma, Cristian, Punzalan, Rubio, navel, miriam, Amezcua, Natalee, Jani, Jitesh, Sharma, Jay

“…Three-dimensional (3D) culture of cancer cell lines has long been advocated as a better model of the malignant phenotype that is most closely related to…”
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Abstract 4408: Targeting cancer stem cells as potential new therapy for pancreatic cancer by Cleary, John P., Raman, Divya, Punzalan, Rubio R., Sharma, Michael Vr, Sharma, Cristian Vr, Sharma, Sherven P., Jani, Jitesh, Sharma, Bhuvnesh, Narayan, Satya, Sharma, Jay P.

“…Pancreatic cancer is the fourth leading cause of cancer mortality in the US, despite significant improvements in diagnostic imaging and operative modalities…”
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A case of stroke and blindness by Mattia, Alicia, Sharma, Michael, Nicolle, Michael, Fraser, J Alexander, Lee, Donald, Hammond, Robert

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