Search Results - "Sharma, Mahak"
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RUFY3 links Arl8b and JIP4-Dynein complex to regulate lysosome size and positioning
Published in Nature communications (21-03-2022)“…The bidirectional movement of lysosomes on microtubule tracks regulates their whole-cell spatial arrangement. Arl8b, a small GTP-binding (G) protein, promotes…”
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DQ-Red BSA Trafficking Assay in Cultured Cells to Assess Cargo Delivery to Lysosomes
Published in Bio-protocol (05-10-2017)“…Lysosomes are the terminal end of the endocytic pathway having acidic environment required for active hydrolases that degrade the cargo delivered to these…”
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Prioritizing the Critical Factors of Cloud Computing Adoption Using Multi-criteria Decision-making Techniques
Published in Global business review (01-02-2020)“…Cloud Computing (CC) is a paradigm shift with the potential of transforming the information and communication technology (ICT) industry. ICT is an integral…”
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4
CD8α-CI-M6PR Particle Motility Assay to Study the Retrograde Motion of CI-M6PR Receptors in Cultured Living Cells
Published in Bio-protocol (05-05-2024)“…The cation-independent mannose 6-phosphate receptors (CI-M6PR) bind newly synthesized mannose 6-phosphate (Man-6-P)-tagged enzymes in the Golgi and transport…”
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The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes
Published in Journal of cell science (01-05-2015)“…The homotypic fusion and protein sorting (HOPS) complex is a multi-subunit complex conserved from yeast to mammals that regulates late endosome and lysosome…”
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Disruptive Technologies in Smart Farming: An Expanded View with Sentiment Analysis
Published in AgriEngineering (01-06-2022)“…Smart Farming (SF) is an emerging technology in the current agricultural landscape. The aim of Smart Farming is to provide tools for various agricultural and…”
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SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle
Published in Nature communications (06-03-2024)“…SARS-CoV-2, the causative agent of COVID-19, uses the host endolysosomal system for entry, replication, and egress. Previous studies have shown that the…”
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Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type in Mycobacterium tuberculosis Infection
Published in The Journal of immunology (1950) (01-05-2018)“…is an extremely successful pathogen, and its success is widely attributed to its ability to manipulate the intracellular environment of macrophages. A central…”
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Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication
Published in PLoS pathogens (01-10-2017)“…Salmonella enterica serovar typhimurium extensively remodels the host late endocytic compartments to establish its vacuolar niche within the host cells…”
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MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling
Published in Molecular biology of the cell (15-12-2009)“…Endocytic recycling of receptors and lipids occurs via a complex network of tubular and vesicular membranes. EHD1 is a key regulator of endocytosis and…”
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The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis
Published in The Journal of cell biology (04-03-2019)“…Hook proteins are evolutionarily conserved dynein adaptors that promote assembly of highly processive dynein-dynactin motor complexes. Mammals express three…”
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The evolutionary loss of the Eh1 motif in FoxE1 in the lineage of placental mammals
Published in PloS one (27-12-2023)“…Forkhead box E1 (FoxE1) protein is a transcriptional regulator known to play a major role in the development of the thyroid gland. By performing sequence…”
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ABCG2 transporter reduces protein aggregation in cigarette smoke condensate-exposed A549 lung cancer cells
Published in PloS one (05-03-2024)“…Cigarette smoke-induced protein aggregation damages the lung cells in emphysema and COPD; however, lung cancer cells continue to thrive, evolving to persist in…”
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EFFECT OF TYPE OF PHYSICAL ACTIVITY ON THE SLEEP PATTERN OF SPORT PLAYERS
Published in International journal of physiotherapy (01-08-2020)“…Background: Physical activity has been identified as a significant adjuvant in improving quality of life and lowering the cost of medicine. A positive effect…”
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Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity
Published in Molecular biology of the cell (01-12-2013)“…Natural killer (NK) lymphocytes contain lysosome-related organelles (LROs), known as lytic granules, which upon formation of immune synapse with the target…”
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Interactions between EHD proteins and Rab11-FIP2: a role for EHD3 in early endosomal transport
Published in Molecular biology of the cell (01-01-2006)“…Eps15 homology domain (EHD) 1 enables membrane recycling by controlling the exit of internalized molecules from the endocytic recycling compartment (ERC) en…”
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The relation between alexithymia, eating attitude, and sleep pattern among university students during the lockdown period of COVID-19 pandemic
Published in Saudi Journal for Health Sciences (01-05-2023)“…Background: COVID-19 lockdown's impact on physical and mental health includes increased prevalence of alexithymia (difficulty recognizing emotions) among…”
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The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes
Published in The Journal of cell biology (03-04-2017)“…Endocytic, autophagic, and phagocytic vesicles move on microtubule tracks to fuse with lysosomes. Small GTPases, such as Rab7 and Arl8b, recruit their…”
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Mechanism for the Selective Interaction of C-terminal Eps15 Homology Domain Proteins with Specific Asn-Pro-Phe-containing Partners
Published in The Journal of biological chemistry (19-03-2010)“…Epidermal growth factor receptor tyrosine kinase substrate 15 (Eps15) homology (EH)-domain proteins can be divided into two classes: those with an N-terminal…”
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Nevus Lipomatosus Cutaneous Superficialis with Unusual Presentation over the Nipple
Published in Indian journal of dermatology (01-07-2017)“…Physical examination of the swellings over the nipple and sacral region revealed multiple, soft, skin-colored to hyperpigmented papules, and nodules measuring…”
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