Search Results - "Sharma, Kuhu"
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Fluvoxamine maleate alleviates amyloid-beta load and neuroinflammation in 5XFAD mice to ameliorate Alzheimer disease pathology
Published in Frontiers in immunology (29-07-2024)“…Alzheimer pathology (AD) is characterized by the deposition of amyloid beta (Aβ) and chronic neuroinflammation, with the NLRP3 inflammasome playing a…”
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2
Correction to: Kinesins: Motor Proteins as Novel Target for the Treatment of Chronic Pain
Published in Molecular neurobiology (2021)“…The original version of this article unfortunately contained mistakes…”
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3
Flurbiprofen inhibits heme induced NLRP3 inflammasome in Berkeley sickle cell disease mice
Published in Frontiers in pharmacology (26-04-2023)“…Sickle cell disease (SCD) is accompanied by several complications, which emanate from the sickling of erythrocytes due to a point mutation in the -globin chain…”
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4
Pharmacokinetic Assessment of Rottlerin from Mallotus philippensis Using a Highly Sensitive Liquid Chromatography–Tandem Mass Spectrometry-Based Bioanalytical Method
Published in ACS omega (07-12-2021)“…Rottlerin is a key bioactive phytoconstituent present in the pericarp of Mallotus philippensis. It shows promising multifaceted pharmacological actions against…”
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5
ADME/PK Insights of Crocetin: A Molecule Having an Unusual Chemical Structure with Druglike Features
Published in ACS omega (14-05-2024)“…Crocetin is a promising phyto-based molecule to treat Alzheimer’s disease (AD). The chemical structure of crocetin is incongruent with various standard…”
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Overlapping of Transphobia and Transliberation in Mainstream Transgender Hindi Cinema: Chandigarh Kare Aashique
Published in Indian literature (New Delhi) (01-05-2024)Get full text
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7
Astaxanthin ameliorates behavioral and biochemical alterations in in-vitro and in-vivo model of neuropathic pain
Published in Neuroscience letters (01-05-2018)“…•Astaxanthin fits into the inhibitory binding pocket of NMDA receptor (NR2B) which is known to be involved in nociception.•This suggests that astaxanthin may…”
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8
Cannabidiol-Based Prodrugs: Synthesis and Bioevaluation
Published in ACS medicinal chemistry letters (08-02-2024)“…Cannabidiol (CBD 1) is a nonpsychotic cannabinoid-based drug approved by the U.S. FDA for treating refractory epilepsy, namely, Lennox–Gastaut and Dravet…”
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Assessment of the CYP1A2 Inhibition-Mediated Drug Interaction Potential for Pinocembrin Using In Silico, In Vitro, and In Vivo Approaches
Published in ACS omega (14-06-2022)“…Pinocembrin, a bioflavonoid, is extensively used in complementary/alternative medicine. It turns out as a promising candidate against neurodegenerative…”
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10
Crocetin Delays Brain and Body Aging by Increasing Cellular Energy Levels in Aged C57BL/6J Mice
Published in ACS pharmacology & translational science (11-10-2024)“…Aging is usually accompanied by mitochondrial dysfunction, reduced energy levels, and cell death in the brain and other tissues. Mitochondria play a crucial…”
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11
Kinesins: Motor Proteins as Novel Target for the Treatment of Chronic Pain
Published in Molecular neurobiology (01-06-2019)“…Kinesins are one of the neoteric and efficacious targets recently reported to play an important role in the initiation and progression of chronic pain…”
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12
Effect of Myricetin on CYP2C8 Inhibition to Assess the Likelihood of Drug Interaction Using In Silico, In Vitro, and In Vivo Approaches
Published in ACS omega (19-04-2022)“…Myricetin, a bioflavonoid, is widely used as functional food/complementary medicine and has promising multifaceted pharmacological actions against…”
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13
Implementation of the meshed tree algorithm on a switched network
Published 01-01-2016“…Loop avoidance is a critical component of switched networks. Protocols like STP, RSTP, TRILL, etc solve this problem in different ways, but there is room for…”
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Dissertation