Search Results - "Sharma, Kuhu"

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  1. 1

    Fluvoxamine maleate alleviates amyloid-beta load and neuroinflammation in 5XFAD mice to ameliorate Alzheimer disease pathology by Kaur, Sukhleen, Sharma, Kuhu, Sharma, Ankita, Sandha, Kamalpreet Kaur, Ali, Syed Mudassir, Ahmed, Riyaz, Ramajayan, P, Singh, Parvinder Pal, Ahmed, Zabeer, Kumar, Ajay

    Published in Frontiers in immunology (29-07-2024)
    “…Alzheimer pathology (AD) is characterized by the deposition of amyloid beta (Aβ) and chronic neuroinflammation, with the NLRP3 inflammasome playing a…”
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    Journal Article
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    Flurbiprofen inhibits heme induced NLRP3 inflammasome in Berkeley sickle cell disease mice by Kour, Dilpreet, Ali, Mehboob, Khajuria, Parul, Sharma, Kuhu, Ghosh, Palash, Kaur, Sukhleen, Mahajan, Surbhi, Ramajayan, P, Bharate, Sonali S, Bhardwaj, Subhash, Sawant, Sanghapal D, Reddy, D Srinivasa, Kumar, Ajay

    Published in Frontiers in pharmacology (26-04-2023)
    “…Sickle cell disease (SCD) is accompanied by several complications, which emanate from the sickling of erythrocytes due to a point mutation in the -globin chain…”
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    Journal Article
  4. 4

    Pharmacokinetic Assessment of Rottlerin from Mallotus philippensis Using a Highly Sensitive Liquid Chromatography–Tandem Mass Spectrometry-Based Bioanalytical Method by Manhas, Diksha, Gour, Abhishek, Bhardwaj, Nivedita, Sharma, Deepak K, Sharma, Kuhu, Vij, Bhavna, Jain, Shreyans K, Singh, Gurdarshan, Nandi, Utpal

    Published in ACS omega (07-12-2021)
    “…Rottlerin is a key bioactive phytoconstituent present in the pericarp of Mallotus philippensis. It shows promising multifaceted pharmacological actions against…”
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    Journal Article
  5. 5

    ADME/PK Insights of Crocetin: A Molecule Having an Unusual Chemical Structure with Druglike Features by Manhas, Diksha, Dhiman, Sumit, Kour, Harpreet, Kour, Dilpreet, Sharma, Kuhu, Wazir, Priya, Vij, Bhavna, Kumar, Ajay, Sawant, Sanghapal D., Ahmed, Zabeer, Nandi, Utpal

    Published in ACS omega (14-05-2024)
    “…Crocetin is a promising phyto-based molecule to treat Alzheimer’s disease (AD). The chemical structure of crocetin is incongruent with various standard…”
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    Journal Article
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    Astaxanthin ameliorates behavioral and biochemical alterations in in-vitro and in-vivo model of neuropathic pain by Sharma, Kuhu, Sharma, Dilip, Sharma, Monika, Sharma, Nishant, Bidve, Pankaj, Prajapati, Namrata, Kalia, Kiran, Tiwari, Vinod

    Published in Neuroscience letters (01-05-2018)
    “…•Astaxanthin fits into the inhibitory binding pocket of NMDA receptor (NR2B) which is known to be involved in nociception.•This suggests that astaxanthin may…”
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    Journal Article
  8. 8

    Cannabidiol-Based Prodrugs: Synthesis and Bioevaluation by Singh Cham, Pankaj, Kotwal, Pankul, Sharma, Kuhu, Dhiman, Sumit, Singh, Lakhvinder, Pratap Singh, Varun, Kumar, Ajay, Nandi, Utpal, Pal Singh, Parvinder

    Published in ACS medicinal chemistry letters (08-02-2024)
    “…Cannabidiol (CBD 1) is a nonpsychotic cannabinoid-based drug approved by the U.S. FDA for treating refractory epilepsy, namely, Lennox–Gastaut and Dravet…”
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    Journal Article
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    Assessment of the CYP1A2 Inhibition-Mediated Drug Interaction Potential for Pinocembrin Using In Silico, In Vitro, and In Vivo Approaches by Bhatt, Shipra, Dhiman, Sumit, Kumar, Vinay, Gour, Abhishek, Manhas, Diksha, Sharma, Kuhu, Ojha, Probir Kumar, Nandi, Utpal

    Published in ACS omega (14-06-2022)
    “…Pinocembrin, a bioflavonoid, is extensively used in complementary/alternative medicine. It turns out as a promising candidate against neurodegenerative…”
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    Journal Article
  10. 10

    Crocetin Delays Brain and Body Aging by Increasing Cellular Energy Levels in Aged C57BL/6J Mice by Choudhary, Sushil, Kumar, Vishnu, Sharma, Kuhu, Gour, Abhishek, Sahrawat, Ashish, Jotshi, Anshika, Manhas, Diksha, Nandi, Utpal, Bharate, Sandip B., Ahmed, Zabeer, Kumar, Ajay

    Published in ACS pharmacology & translational science (11-10-2024)
    “…Aging is usually accompanied by mitochondrial dysfunction, reduced energy levels, and cell death in the brain and other tissues. Mitochondria play a crucial…”
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    Journal Article
  11. 11

    Kinesins: Motor Proteins as Novel Target for the Treatment of Chronic Pain by Shantanu, P. A., Sharma, Dilip, Sharma, Monika, Vaidya, Shivani, Sharma, Kuhu, Kalia, Kiran, Tao, Yuan-Xiang, Shard, Amit, Tiwari, Vinod

    Published in Molecular neurobiology (01-06-2019)
    “…Kinesins are one of the neoteric and efficacious targets recently reported to play an important role in the initiation and progression of chronic pain…”
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    Journal Article
  12. 12

    Effect of Myricetin on CYP2C8 Inhibition to Assess the Likelihood of Drug Interaction Using In Silico, In Vitro, and In Vivo Approaches by Bhatt, Shipra, Manhas, Diksha, Kumar, Vinay, Gour, Abhishek, Sharma, Kuhu, Dogra, Ashish, Ojha, Probir Kumar, Nandi, Utpal

    Published in ACS omega (19-04-2022)
    “…Myricetin, a bioflavonoid, is widely used as functional food/complementary medicine and has promising multifaceted pharmacological actions against…”
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    Journal Article
  13. 13

    Implementation of the meshed tree algorithm on a switched network by Sharma, Kuhu

    Published 01-01-2016
    “…Loop avoidance is a critical component of switched networks. Protocols like STP, RSTP, TRILL, etc solve this problem in different ways, but there is room for…”
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    Dissertation