Search Results - "Sharina, Iraida G"

Frequency of Tongue Cleaning Impacts the Human Tongue Microbiome Composition and Enterosalivary Circulation of Nitrate by Tribble, Gena D, Angelov, Nikola, Weltman, Robin, Wang, Bing-Yan, Eswaran, Sridhar V, Gay, Isabel C, Parthasarathy, Kavitha, Dao, Doan-Hieu V, Richardson, Katherine N, Ismail, Nadia M, Sharina, Iraida G, Hyde, Embriette R, Ajami, Nadim J, Petrosino, Joseph F, Bryan, Nathan S

“…The oral microbiome has the potential to provide an important symbiotic function in human blood pressure physiology by contributing to the generation of nitric…”
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Alternative splicing impairs soluble guanylyl cyclase function in aortic aneurysm by Martin, Emil, Golunski, Eva, Laing, Susan T, Estrera, Anthony L, Sharina, Iraida G

“…Nitric oxide (NO) receptor soluble guanylyl cyclase (sGC) is a key regulator of several important vascular functions and is important for maintaining…”
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Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells by Cote, Gilbert J, Zhu, Wen, Thomas, Anthony, Martin, Emil, Murad, Ferid, Sharina, Iraida G

“…Soluble guanylyl cyclase (sGC) plays a central role in nitric oxide (NO)-mediated signal transduction in the cardiovascular, nervous and gastrointestinal…”
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A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases by Kots, Alexander Y, Martin, Emil, Sharina, Iraida G, Murad, Ferid

“…Here, we review the early studies on cGMP, guanylyl cyclases, and cGMP-dependent protein kinases to facilitate understanding of development of this exciting…”
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The Role of Reactive Oxygen and Nitrogen Species in the Expression and Splicing of Nitric Oxide Receptor by Sharina, Iraida G, Martin, Emil

“…Nitric oxide (NO)-dependent signaling is critical to many cellular functions and physiological processes. Soluble guanylyl cyclase (sGC) acts as an NO receptor…”
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Dynamic interplay between nitration and phosphorylation of tubulin cofactor B in the control of microtubule dynamics by Rayala, Suresh K, Martin, Emil, Sharina, Iraida G, Molli, Poonam R, Wang, Xiaoping, Jacobson, Raymond, Murad, Ferid, Kumar, Rakesh

“…Tubulin cofactor B (TCoB) plays an important role in microtubule dynamics by facilitating the dimerization of α- and β-tubulin. Recent evidence suggests that…”
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alpha 1 Soluble Guanylyl Cyclase (sGC) Splice Forms as Potential Regulators of Human sGC Activity by Sharina, Iraida G, Jelen, Filip, Bogatenkova, Elena P, Thomas, Anthony, Martin, Emil, Murad, Ferid

“…Soluble guanylyl cyclase (sGC), a key protein in the NO/cGMP signaling pathway, is an obligatory heterodimeric protein composed of one alpha - and one beta…”
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α1 Soluble Guanylyl Cyclase (sGC) Splice Forms as Potential Regulators of Human sGC Activity by Sharina, Iraida G., Jelen, Filip, Bogatenkova, Elena P., Thomas, Anthony, Martin, Emil, Murad, Ferid

“…Soluble guanylyl cyclase (sGC), a key protein in the NO/cGMP signaling pathway, is an obligatory heterodimeric protein composed of one α- and one β-subunit…”
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Nitric oxide receptor soluble guanylyl cyclase undergoes splicing regulation in differentiating human embryonic cells by Sharin, Vladislav G, Mujoo, Kalpana, Kots, Alexander Y, Martin, Emil, Murad, Ferid, Sharina, Iraida G

“…Nitric oxide (NO), an important mediator molecule in mammalian physiology, initiates a number of signaling mechanisms by activating the enzyme soluble guanylyl…”
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RNA splicing in regulation of nitric oxide receptor soluble guanylyl cyclase by Sharina, Iraida G., Cote, Gilbert J., Martin, Emil, Doursout, Marie-Francoise, Murad, Ferid

“…► We summarize data on sGC regulation by transcription, mRNA stability and splicing. ► We abridge information on sGC splicing from literature and genomic…”
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Synthesis of New Hydrophilic and Hydrophobic Cobinamides as NO-Independent sGC Activators by Proinsias, Keith ó, Giedyk, Maciej, Sharina, Iraida G, Martin, Emil, Gryko, Dorota

“…Herein, the synthesis of novel hydrophobic and hydrophilic cobinamides via aminolysis of vitamin B12 derivatives that activate soluble guanyl cyclase (sGC) is…”
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Abstract 5218: Corrin-mediated Activation of Nitric Oxide Receptor and Its Cardiovascular Consequences by Martin, Emil, Sharina, Iraida G, Liang, Yang Yan, Doursout, Marie-Francoise

“…Abstract only Soluble guanylyl cyclase (sGC) is the recognized receptor for nitric oxide (NO) messenger molecule. In addition to NO, several allosteric…”
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CCAAT-Binding Factor Regulates Expression of the β1Subunit of Soluble Guanylyl Cyclase Gene in the BE2 Human Neuroblastoma Cell Line by Sharina, Iraida G., Martin, Emil, Thomas, Anthony, Uray, Karen L., Murad, Ferid

“…Soluble guanylyl cyclase (sGC) is a cytosolic enzyme producing the intracellular messenger cyclic guanosine monophosphate (cGMP) on activation with nitric…”
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Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis by Zhao, R, Sharina, I G, Goldman, I D

“…Chemical mutagenesis with N-methyl-N-nitrosourea was employed to study the pattern of mutations in the reduced folate carrier (RFC1) that results in…”
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CCAAT-binding factor regulates expression of the beta1 subunit of soluble guanylyl cyclase gene in the BE2 human neuroblastoma cell line by Sharina, Iraida G., Martin, Emil, Thomas, Anthony, Uray, Karen L., Murad, Ferid

“…Soluble guanylyl cyclase (sGC) is a cytosolic enzyme producing the intracellular messenger cyclic guanosine monophosphate (cGMP) on activation with nitric…”
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Mutational analysis of the functional role of conserved arginine and lysine residues in transmembrane domains of the murine reduced folate carrier by Sharina, I G, Zhao, R, Wang, Y, Babani, S, Goldman, I D

“…The reduced folate carrier (RFC1) plays a major role in the delivery of folates into mammalian cells. RFC1 is an anion exchanger with seven conserved…”
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Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function by Sharina, Iraida G., Zhao, Rongbao, Wang, Yanhua, Babani, Solomon, Goldman, I.David

“…The reduced folate carrier (RFC1), a member of the major facilitative superfamily, generates uphill transport of folates into cells through an exchange…”
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Impact of Overexpression of the Reduced Folate Carrier (RFC1), an Anion Exchanger, on Concentrative Transport in Murine L1210 Leukemia Cells by Zhao, Rongbao, Seither, Richard, Brigle, Kevin E., Sharina, Iraida G., Wang, Pi J., Goldman, I. David

“…Transport of reduced folates in murine leukemia cells is mediated by the bidirectional reduced folate carrier (RFC1) and independent unidirectional exit pumps…”
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Total Body Irradiation Affects the Integrity of Nitric Oxide/cGMP Signaling in Rat Tissues by Doursout, Marie‐Francoise, Martin, Emil, Garg, Harsha, Bryan, Nathan, Conyers, Jodie L., Sharina, Iraida G.

“…Introduction Vascular injury is one of the most common effects of radiation exposure and its molecular mechanisms remain unknown. NO/cGMP signaling pathway is…”
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α1 Soluble Guanylyl Cyclase (sGC) Splice Forms as Potential Regulators of Human sGC Activity by Iraida G. Sharina, Filip Jelen, Elena P. Bogatenkova, Anthony Thomas, Emil Martin, Ferid Murad

“…Soluble guanylyl cyclase (sGC), a key protein in the NO/cGMP signaling pathway, is an obligatory heterodimeric protein composed of one α- and one β-subunit…”
Get full text