Search Results - "Sharina, I G"

The fibrate gemfibrozil is a NO‐ and haem‐independent activator of soluble guanylyl cyclase: in vitro studies by Sharina, I G, Sobolevsky, M, Papakyriakou, A, Rukoyatkina, N, Spyroulias, G A, Gambaryan, S, Martin, E

“…Background and Purpose Fibrates are a class of drugs widely used to treat dyslipidaemias. They regulate lipid metabolism and act as PPARα agonists. Clinical…”
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Genomic Organization of α 1 and β 1 Subunits of the Mammalian Soluble Guanylyl Cyclase Genes by Sharina, I. G., Krumenacker, J. S., Martin, E., Murad, F.

“…The structures of the genes encoding the α1and β1subunits of murine soluble guanylyl cyclase (sGC) were determined. Full-length cDNAs isolated from mouse lungs…”
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Genomic organization of α1 and β1 subunits of the mammalian soluble guanylyl cyclase genes by Sharina, I. G., Krumenacker, J. S., Martin, E., Murad, F.

“…The structures of the genes encoding the α 1 and β 1 subunits of murine soluble guanylyl cyclase (sGC) were determined. Full-length cDNAs isolated from mouse…”
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Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis by Zhao, R, Sharina, I G, Goldman, I D

“…Chemical mutagenesis with N-methyl-N-nitrosourea was employed to study the pattern of mutations in the reduced folate carrier (RFC1) that results in…”
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Mutational analysis of the functional role of conserved arginine and lysine residues in transmembrane domains of the murine reduced folate carrier by Sharina, I G, Zhao, R, Wang, Y, Babani, S, Goldman, I D

“…The reduced folate carrier (RFC1) plays a major role in the delivery of folates into mammalian cells. RFC1 is an anion exchanger with seven conserved…”
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Impact of Overexpression of the Reduced Folate Carrier (RFC1), an Anion Exchanger, on Concentrative Transport in Murine L1210 Leukemia Cells by Zhao, Rongbao, Seither, Richard, Brigle, Kevin E., Sharina, Iraida G., Wang, Pi J., Goldman, I. David

“…Transport of reduced folates in murine leukemia cells is mediated by the bidirectional reduced folate carrier (RFC1) and independent unidirectional exit pumps…”
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CCAAT-binding factor regulates expression of the beta sub(1) subunit of soluble guanylyl cyclase gene in the BE2 human neuroblastoma cell line by Sharina, I G, Martin, E, Thomas, A, Uray, K L, Murad, F

“…Soluble guanylyl cyclase (sGC) is a cytosolic enzyme producing the intracellular messenger cyclic guanosine monophosphate (cGMP) on activation with nitric…”
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Genomic organization of alpha1 and beta1 subunits of the mammalian soluble guanylyl cyclase genes by Sharina, I G, Krumenacker, J S, Martin, E, Murad, F

“…The structures of the genes encoding the alpha(1) and beta(1) subunits of murine soluble guanylyl cyclase (sGC) were determined. Full-length cDNAs isolated…”
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Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function by Sharina, Iraida G., Zhao, Rongbao, Wang, Yanhua, Babani, Solomon, Goldman, I.David

“…The reduced folate carrier (RFC1), a member of the major facilitative superfamily, generates uphill transport of folates into cells through an exchange…”
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ANSA analysis. III. Synthesis of aminonaphthalinesulfonamide chromogenic substrates for protease analysis by Kazantsev, A G, Kuznetsov, N V, Iakhimovich, A D, Sharina, I G, Nezavibat'ko, V N, Nedospasov, A A

“…A review of synthetic methods of peptide substrates containing aminonaphthalenesulphonamide (ANSA) as the detected leaving group is presented. Variations of…”
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ANSA analysis. II. Aminonaphthalenesulfonamides--detecting groups for polysubstrate analysis of proteases by Trushkin, A M, Kazantsev, A G, Kuznetsov, N V, Iakhimovich, A D, Moguchaia, G Iu, Rodina, E V, Gridneva, N A, Sharina, I G, Nedospasov, A A

“…The properties and synthetic methods of aminonaphthalenesulfonamides (ANSA) used as detectable groups of protease substrates are described. A list of chemical…”
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