Search Results - "Shariatgorji, Mohammadreza"

Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging by Shariatgorji, Mohammadreza, Nilsson, Anna, Fridjonsdottir, Elva, Vallianatou, Theodosia, Källback, Patrik, Katan, Luay, Sävmarker, Jonas, Mantas, Ioannis, Zhang, Xiaoqun, Bezard, Erwan, Svenningsson, Per, Odell, Luke R., Andrén, Per E.

“…We present a mass spectrometry imaging (MSI) approach for the comprehensive mapping of neurotransmitter networks in specific brain regions. Our…”
Get full text

msIQuant – Quantitation Software for Mass Spectrometry Imaging Enabling Fast Access, Visualization, and Analysis of Large Data Sets by Källback, Patrik, Nilsson, Anna, Shariatgorji, Mohammadreza, Andrén, Per E

“…This paper presents msIQuant, a novel instrument- and manufacturer-independent quantitative mass spectrometry imaging software suite that uses the standardized…”
Get full text

Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition by Vallianatou, Theodosia, Shariatgorji, Mohammadreza, Nilsson, Anna, Fridjonsdottir, Elva, Källback, Patrik, Schintu, Nicoletta, Svenningsson, Per, Andrén, Per E

“…The neurotransmitter of the cholinergic system, acetylcholine plays a major role in the brain's cognitive function and is involved in neurodegenerative…”
Get full text

Mass Spectrometry Imaging in Drug Development by Nilsson, Anna, Goodwin, Richard J. A, Shariatgorji, Mohammadreza, Vallianatou, Theodosia, Webborn, Peter J. H, Andrén, Per E

Get full text

Direct Targeted Quantitative Molecular Imaging of Neurotransmitters in Brain Tissue Sections by Shariatgorji, Mohammadreza, Nilsson, Anna, Goodwin, Richard J.A., Källback, Patrik, Schintu, Nicoletta, Zhang, Xiaoqun, Crossman, Alan R., Bezard, Erwan, Svenningsson, Per, Andren, Per E.

“…Current neuroimaging techniques have very limited abilities to directly identify and quantify neurotransmitters from brain sections. We have developed a…”
Get full text

Pyrylium Salts as Reactive Matrices for MALDI-MS Imaging of Biologically Active Primary Amines by Shariatgorji, Mohammadreza, Nilsson, Anna, Källback, Patrik, Karlsson, Oskar, Zhang, Xiaoqun, Svenningsson, Per, Andren, Per E.

“…Many neuroactive substances, including endogenous biomolecules, environmental compounds, and pharmaceuticals possess primary amine functional groups. Among…”
Get full text

Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections by Källback, Patrik, Shariatgorji, Mohammadreza, Nilsson, Anna, Andrén, Per E.

“…MALDI MS imaging has been extensively used to produce qualitative distribution maps of proteins, peptides, lipids, small molecule pharmaceuticals and their…”
Get full text

How Does the Sweet Violet ( Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System by Slazak, Blazej, Kapusta, Małgorzata, Strömstedt, Adam A, Słomka, Aneta, Krychowiak, Marta, Shariatgorji, Mohammadreza, Andrén, Per E, Bohdanowicz, Jerzy, Kuta, Elżbieta, Göransson, Ulf

“…Cyclotides are cyclic plant polypeptides of 27-37 amino acid residues. They have been extensively studied in bioengineering and drug development contexts…”
Get full text

Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry by Shariatgorji, Mohammadreza, Strittmatter, Nicole, Nilsson, Anna, Källback, Patrik, Alvarsson, Alexandra, Zhang, Xiaoqun, Vallianatou, Theodosia, Svenningsson, Per, Goodwin, Richard J.A., Andren, Per E.

“…With neurological processes involving multiple neurotransmitters and neuromodulators, it is important to have the ability to directly map and quantify multiple…”
Get full text

Controlled-pH Tissue Cleanup Protocol for Signal Enhancement of Small Molecule Drugs Analyzed by MALDI-MS Imaging by Shariatgorji, Mohammadreza, Källback, Patrik, Gustavsson, Lena, Schintu, Nicoletta, Svenningsson, Per, Goodwin, Richard J.A, Andren, Per E

“…The limit of detection of low-molecular weight compounds in tissue sections, analyzed by matrix assisted laser desorption ionization mass spectrometry imaging…”
Get full text

Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry by Shariatgorji, Mohammadreza, Nilsson, Anna, Bonta, Maximilian, Gan, Jinrui, Marklund, Niklas, Clausen, Fredrik, Källback, Patrik, Loden, Henrik, Limbeck, Andreas, Andrén, Per E.

“…•Imaging of elements in biological tissues using laser ablation mass spectrometry.•Quantitative imaging of elements in kidney and in traumatic brain injury…”
Get full text

Deuterated Matrix-Assisted Laser Desorption Ionization Matrix Uncovers Masked Mass Spectrometry Imaging Signals of Small Molecules by Shariatgorji, Mohammadreza, Nilsson, Anna, Goodwin, Richard J. A, Svenningsson, Per, Schintu, Nicoletta, Banka, Zoltan, Kladni, Laszlo, Hasko, Tibor, Szabo, Andras, Andren, Per E

“…D4-α-Cyano-4-hydroxycinnamic acid (D4-CHCA) has been synthesized for use as a matrix for matrix-assisted laser desorption ionization-mass spectrometry…”
Get full text

Screening and Quantification of Pesticides in Water Using a Dual-Function Graphitized Carbon Black Disk by Amini, Nahid, Shariatgorji, Mohammadreza, Crescenzi, Carlo, Thorsén, Gunnar

“…A simple platform for combining solid phase extraction (SPE) and surface-assisted laser desorption ionization mass spectrometry (SALDI-MS) of extracted…”
Get full text

Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or β-Phenylethylamine by Zhang, Xiaoqun, Mantas, Ioannis, Alvarsson, Alexandra, Yoshitake, Takashi, Shariatgorji, Mohammadreza, Pereira, Marcela, Nilsson, Anna, Kehr, Jan, Andrén, Per E, Millan, Mark J, Chergui, Karima, Svenningsson, Per

“…The trace amine-associated receptor 1 (TAAR1) is expressed by dopaminergic neurons, but the precise influence of trace amines upon their functional activity…”
Get full text

Light-Induced Water Oxidation by a Ru complex Containing a Bio-Inspired Ligand by Kärkäs, Markus D., Johnston, Eric V., Karlsson, Erik A., Lee, Bao-Lin, Åkermark, Torbjörn, Shariatgorji, Mohammadreza, Ilag, Leopold, Hansson, Örjan, Bäckvall, Jan-E., Åkermark, Björn

“…The new Ru complex 8 containing the bio‐inspired ligand 7 was successfully synthesized and characterized. Complex 8 efficiently catalyzes water oxidation using…”
Get full text

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology by SHARIATGORJI, Mohammadreza, SVENNINGSSON, Per, ANDREN, Per E

“…Mass spectrometry imaging is a powerful tool for directly determining the distribution of proteins, peptides, lipids, neurotransmitters, metabolites and drugs…”
Get full text

α-synuclein–lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson’s disease patients by Paslawskia, Wojciech, Zareba-Paslawskaa, Justyna, Zhanga, Xiaoqun, Hölzla, Katharina, Wadensten, Henrik, Shariatgorji, Mohammadreza, Janelidze, Shorena, Hansson, Oskar, Forsgren, Lars, Andrén, Per E., Svenningsson, Per

“…The progressive accumulation, aggregation, and spread of α-synuclein (αSN) are common hallmarks of Parkinson’s disease (PD) pathology. Moreover, numerous…”
Get full text

Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy by Hulme, Heather, Fridjonsdottir, Elva, Gunnarsdottir, Halla, Vallianatou, Theodosia, Zhang, Xiaoqun, Wadensten, Henrik, Shariatgorji, Reza, Nilsson, Anna, Bezard, Erwan, Svenningsson, Per, Andrén, Per E.

“…Neuropeptides are important signalling molecules in the brain and alterations in their expression levels have been linked to neurological disorders such as…”
Get full text

TAAR1-Dependent and -Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition by Mantas, Ioannis, Vallianatou, Theodosia, Yang, Yunting, Shariatgorji, Mohammadreza, Kalomoiri, Maria, Fridjonsdottir, Elva, Millan, Mark J., Zhang, Xiaoqun, Andrén, Per E., Svenningsson, Per

“…Monoamine oxidase inhibitors (MAOIs) exert therapeutic actions by elevating extracellular levels of monoamines in the brain. Irreversible MAOIs cause serious…”
Get full text

Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers by Källback, Patrik, Vallianatou, Theodosia, Nilsson, Anna, Shariatgorji, Reza, Schintu, Nicoletta, Pereira, Marcela, Barré, Florian, Wadensten, Henrik, Svenningsson, Per, Andrén, Per E

“…Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is an established tool in drug development, which enables visualization of…”
Get full text