Search Results - "Shargh, Vahid Heravi"
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Micro/nanoparticle adjuvants for antileishmanial vaccines: Present and future trends
Published in Vaccine (21-01-2013)“…Highlights ► A suitable adjuvant is needed to improve the efficacy of antileishmanial vaccines. ► Particulate adjuvants are the valuable strategy to enhance…”
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Antibody-targeted biodegradable nanoparticles for cancer therapy
Published in Nanomedicine (01-01-2016)“…The use of nanotechnology has great potentials to revolutionize the future cancer diagnosis and therapy. In this context, various nanoparticles (NPs) have been…”
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Gelatin-albumin hybrid nanoparticles as matrix metalloproteinases-degradable delivery systems for breast cancer therapy
Published in Nanomedicine (London, England) (01-05-2017)“…To develop matrix metalloproteinase-responsive gelatin-albumin hybrid nanoparticles encapsulating a selective tropomyosin receptor kinase A (TrkA) inhibitor…”
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Surface-modified cationic liposomes with a matrix metalloproteinase-degradable polyethylene glycol derivative improved doxorubicin delivery in murine colon cancer
Published in Journal of liposome research (01-06-2024)“…PEGylation is a commonly used approach to prolong the blood circulation time of cationic liposomes. However, PEGylation is associated with the "PEG dilemma",…”
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Chemosensitization of Temozolomide-Resistant Pediatric Diffuse Midline Glioma Using Potent Nanoencapsulated Forms of a N(3)-Propargyl Analogue
Published in ACS applied materials & interfaces (04-08-2021)“…The lack of clinical response to the alkylating agent temozolomide (TMZ) in pediatric diffuse midline/intrinsic pontine glioma (DIPG) has been associated with…”
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Cationic liposomes formulated with a novel whole Leishmania lysate (WLL) as a vaccine for leishmaniasis in murine model
Published in Immunobiology (1979) (01-06-2018)“…Although there have been numerous attempts to develop a successful vaccine against leishmaniasis, based on the clinical trial in this field, no vaccine against…”
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Induction of protection against leishmaniasis in susceptible BALB/c mice using simple DOTAP cationic nanoliposomes containing soluble Leishmania antigen (SLA)
Published in Acta tropica (01-12-2013)“…•DOTAP nanoliposomes containing 1mg/ml of SLA induce an efficient protection against leishmaniasis.•DOTAP nanoliposomes containing 1mg/ml of SLA reduce lesion…”
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Doxorubicin-loaded liposomes surface engineered with the matrix metalloproteinase-2 cleavable polyethylene glycol conjugate for cancer therapy
Published in Cancer nanotechnology (2023)“…Background Colorectal cancer is one of the prominent leading causes of fatality worldwide. Despite recent advancements within the field of cancer therapy, the…”
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The role of liposome size on the type of immune response induced in BALB/c mice against leishmaniasis: rgp63 as a model antigen
Published in Experimental parasitology (01-12-2012)“…[Display omitted] ► Liposome’s size plays a significant role in the type of generated immune response. ► A liposomal delivery system was developed to induce…”
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Cationic liposomes containing soluble Leishmania antigens (SLA) plus CpG ODNs induce protection against murine model of leishmaniasis
Published in Parasitology research (1987) (01-07-2012)“…Development of an effective vaccine against leishmaniasis is possible due to the fact that individuals cured from cutaneous leishmaniasis (CL) are protected…”
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Albumin hybrid nanoparticles loaded with tyrosine kinase A inhibitor GNF-5837 for targeted inhibition of breast cancer cell growth and invasion
Published in International journal of pharmaceutics (30-12-2016)“…Delivery of poorly soluble GNF-5837 via albumin hybrid nanoparticles (GNF-Alb-HNPs) shows significantly superior anticancer efficacy in a panel of breast…”
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Liposomal SLA co-incorporated with PO CpG ODNs or PS CpG ODNs induce the same protection against the murine model of leishmaniasis
Published in Vaccine (06-06-2012)“…Highlights ► The nuclease-resistant (PS) or -sensitive (PO) CpG ODNs were used as adjuvants. ► A liposomal delivery system was developed to protect PO CpG ODNs…”
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