Search Results - "Shardell, M."

Translational research on chemical nerve agents by Jett, David A., Spriggs, Shardell M.

“…This special issue will describe cutting-edge translational research on the development of safe and effective therapeutics for treating exposure to toxic…”
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The vaginal metabolome and microbiota of cervical HPV‐positive and HPV‐negative women: a cross‐sectional analysis by Borgogna, JC, Shardell, MD, Santori, EK, Nelson, TM, Rath, JM, Glover, ED, Ravel, J, Gravitt, PE, Yeoman, CJ, Brotman, RM

“…Objective Characterise the vaginal metabolome of cervical HPV‐infected and uninfected women. Design Cross‐sectional. Setting The Center for Health Behavior…”
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A roadmap to build a phenotypic metric of ageing: insights from the Baltimore Longitudinal Study of Aging by Kuo, P.‐L., Schrack, J. A., Shardell, M. D., Levine, M., Moore, A. Z., An, Y., Elango, P., Karikkineth, A., Tanaka, T., Cabo, R., Zukley, L. M., AlGhatrif, M., Chia, C. W., Simonsick, E. M., Egan, J. M., Resnick, S. M., Ferrucci, L.

“…Over the past three decades, considerable effort has been dedicated to quantifying the pace of ageing yet identifying the most essential metrics of ageing…”
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An evidence-based comparison of operational criteria for the presence of sarcopenia by Dam, Thuy-Tien, Peters, Katherine W, Fragala, Maren, Cawthon, Peggy M, Harris, Tamara B, McLean, Robert, Shardell, Michelle, Alley, Dawn E, Kenny, Anne, Ferrucci, Luigi, Guralnik, Jack, Kiel, Douglas P, Kritchevsky, Steve, Vassileva, Maria T, Studenski, Stephanie

“…Several consensus groups have previously published operational criteria for sarcopenia, incorporating lean mass with strength and/or physical performance. The…”
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Cigarette smoking is associated with an altered vaginal tract metabolomic profile by Nelson, T. M., Borgogna, J. C., Michalek, R. D., Roberts, D. W., Rath, J. M., Glover, E. D., Ravel, J., Shardell, M. D., Yeoman, C. J., Brotman, R. M.

“…Cigarette smoking has been associated with both the diagnosis of bacterial vaginosis (BV) and a vaginal microbiota lacking protective Lactobacillus spp. As the…”
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Absolute Strength and Loss of Strength as Predictors of Mobility Decline in Older Adults: The InCHIANTI Study by Hicks, Gregory E., Shardell, Michelle, Alley, Dawn E., Miller, Ram R., Bandinelli, Stefania, Guralnik, Jack, Lauretani, Fulvio, Simonsick, Eleanor M., Ferrucci, Luigi

“…Background. Theoretical definitions of sarcopenia traditionally emphasize age-related loss of muscle strength; however, most analyses of the association…”
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Pain severity as a mediator of the association between depressive symptoms and physical performance in knee osteoarthritis by Rathbun, A.M., Shardell, M.D., Stuart, E.A., Yau, M.S., Gallo, J.J., Schuler, M.S., Hochberg, M.C.

“…Depressive symptoms in knee osteoarthritis (OA) are associated with increased pain severity and declines in physical performance. This study examined whether…”
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Older men who sustain a hip fracture experience greater declines in bone mineral density at the contralateral hip than non-fractured comparators by Rathbun, A. M., Magaziner, J., Shardell, M. D., Yerges-Armstrong, L. M., Orwig, D., Hicks, G. E., Hochberg, M. C.

“…Summary Men experience declining bone mineral density (BMD) after hip fracture; however, changes attributable to fracture are unknown. This study evaluated the…”
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Interplay Between the Temporal Dynamics of the Vaginal Microbiota and Human Papillomavirus Detection by Brotman, Rebecca M., Shardell, Michelle D., Gajer, Pawel, Tracy, J. Kathleen, Zenilman, Jonathan M., Ravel, Jacques, Gravitt, Patti E.

“…Background. We sought to describe the temporal relationship between vaginal microbiota and human papillomavirus (HPV) detection. Methods. Thirty-two…”
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Methods and recommendations for evaluating and reporting a new diagnostic test by Hess, A. S., Shardell, M., Johnson, J. K., Thom, K. A., Strassle, P., Netzer, G., Harris, A. D.

“…No standardized guidelines exist for the biostatistical methods appropriate for studies evaluating diagnostic tests. Publication recommendations such as the…”
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Estimating the impact of depressive symptoms on osteoarthritis pain using marginal structural models: Data from the Osteoarthritis Initiative by Rathbun, A.M, Stuart, E, Shardell, M, Yau, M, Hochberg, M

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Depressive symptoms and structural disease progression in knee osteoarthritis: Data from the Osteoarthritis Initiative by Rathbun, A.M, Yau, M, Shardell, M, Stuart, E, Hochberg, M

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Racial disparity in all‐cause mortality among hepatitis C virus‐infected individuals in a general US population, NHANES III by Emmanuel, B., Shardell, M. D., Tracy, L., Kottilil, S., El‐Kamary, S. S.

“…Summary There are few long‐term nationally representative studies of all‐cause mortality among those infected with hepatitis C virus (HCV). When an additional…”
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Effects of aromatase inhibition vs. testosterone in older men with low testosterone: randomized‐controlled trial by Dias, J. P., Melvin, D., Simonsick, E.M., Carlson, O., Shardell, M.D., Ferrucci, L., Chia, C. W., Basaria, S., Egan, J. M.

“…Summary Aging in men is associated with loss of bone mass, impaired physical function and altered body composition. The objective of this proof‐of‐concept…”
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Grip strength cutpoints for the identification of clinically relevant weakness by Alley, Dawn E, Shardell, Michelle D, Peters, Katherine W, McLean, Robert R, Dam, Thuy-Tien L, Kenny, Anne M, Fragala, Maren S, Harris, Tamara B, Kiel, Douglas P, Guralnik, Jack M, Ferrucci, Luigi, Kritchevsky, Stephen B, Studenski, Stephanie A, Vassileva, Maria T, Cawthon, Peggy M

“…Weakness is common and contributes to disability, but no consensus exists regarding a strength cutpoint to identify persons at high risk. This analysis,…”
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Statistical Analysis and Application of Quasi Experiments to Antimicrobial Resistance Intervention Studies by Eliopoulos, George M., Shardell, Michelle, Harris, Anthony D., El-Kamary, Samer S., Furuno, Jon P., Miller, Ram R., Perencevich, Eli N.

“…Quasi-experimental study designs are frequently used to assess interventions that aim to limit the emergence of antimicrobial-resistant pathogens. However,…”
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Muscle Quality, Strength, and Lower Extremity Physical Performance in the Baltimore Longitudinal Study of Aging by Chiles Shaffer, N, Fabbri, E, Ferrucci, L, Shardell, M, Simonsick, E M, Studenski, S

“…Muscle quality is defined as the force generated by each volumetric unit of muscle tissue. No consensus exists on an optimal measure of muscle quality,…”
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Improving community ambulation after hip fracture: protocol for a randomised, controlled trial by Orwig, D, Mangione, KK, Baumgarten, M, Terrin, M, Fortinsky, R, Kenny, AM, Gruber-Baldini, AL, Beamer, B, Tosteson, ANA, Shardell, M, Magder, L, Binder, E, Koval, K, Resnick, B, Craik, RL, Magaziner, J

“…Abstract Introduction After a hip fracture in older persons, significant disability often remains; dependency in functional activities commonly persists beyond…”
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Examining Differences in Recovery Outcomes between Male and Female Hip Fracture Patients: Design and Baseline Results of a Prospective Cohort Study from the Baltimore Hip Studies by Orwig, D, Hochberg, M C, Gruber-Baldini, A L, Resnick, B, Miller, R R, Hicks, G E, Cappola, A R, Shardell, M, Sterling, R, Hebel, J R, Johnson, R, Magaziner, J

“…Incidence of hip fractures in men is expected to increase, yet little is known about consequences of hip fracture in men compared to women. It is important to…”
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Testosterone vs. aromatase inhibitor in older men with low testosterone: effects on cardiometabolic parameters by Dias, J.P., Shardell, M. D., Carlson, O. D., Melvin, D., Caturegli, G., Ferrucci, L., Chia, C. W., Egan, J. M., Basaria, S.

“…Summary Testosterone (T) replacement is being increasingly offered to older men with age‐related decline in testosterone levels. The effects of long‐term…”
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