Search Results - "Sharda, Anish V."
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Aspirin thromboprophylaxis in joint replacement surgery
Published in Research and practice in thrombosis and haemostasis (01-01-2022)“…Aspirin is commonly used as the only pharmacologic agent for prevention of venous thromboembolism (VTE) after joint replacement surgery in the United States…”
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2
Circulating Protein Disulfide Isomerase Is Associated with Increased Risk of Thrombosis in JAK2 -Mutated Myeloproliferative Neoplasms
Published in Clinical cancer research (15-10-2021)“…Thromboembolic events (TE) are the most common complications of myeloproliferative neoplasms (MPN). Clinical parameters, including patient age and mutation…”
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3
VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2
Published in Blood (10-12-2020)“…von Willebrand factor (VWF) is an essential hemostatic protein that is synthesized in endothelial cells and stored in Weibel-Palade bodies (WPBs)…”
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4
Detection of membrane-bound and soluble antigens by magnetic levitation
Published in Lab on a chip (11-10-2017)“…Magnetic levitation is a technique for measuring the density and the magnetic properties of objects suspended in a paramagnetic field. We describe a novel…”
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Dose-adjusted enoxaparin thromboprophylaxis in hospitalized cancer patients: a randomized, double-blinded multicenter phase 2 trial
Published in Blood advances (26-05-2020)“…Hospitalized patients with cancer are at an increased risk of developing venous thromboembolism (VTE). The recommendation for routine pharmacologic…”
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6
Ralb and Exocyst Regulate Endothelial Cell Von Willebrand Factor Release
Published in Blood (02-11-2023)“…Background: Identification of novel therapeutic targets for pharmacologic modulation of circulating von Willebrand factor (vWF) would be invaluable in…”
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Measurement of shear-activated platelet aggregate formation in non-anticoagulated blood: utility in detection of clopidogrel-aspirin-induced platelet dysfunction
Published in Clinical and applied thrombosis/hemostasis (01-03-2012)“…We studied the ability of a new instrument, the PlaCor PRT that measures shear-induced platelet aggregation in fingerstick, non-anticoagulated blood without…”
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8
Aspirin Thromboprophylaxis in Joint Replacement Surgery
Published in Blood (08-12-2017)“…Introduction. Total knee replacement (TKR) and total hip replacement (THA) surgeries have historically been felt to carry a high risk of post-operative venous…”
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VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex
Published in Blood (13-11-2019)“…von Willebrand factor (vWF) is an essential plasma hemostatic factor that also participates in pathophysiologic processes such as thrombosis, angiogenesis and…”
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Proteomic Profiling of Different Antiphospholipid Antibody-Positive Phenotypes: Results from Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Registry
Published in Blood (02-11-2023)“…Background. Antiphospholipid syndrome (APS) is an autoimmune disease with thrombotic and obstetric complications arising via a model of immunothrombosis…”
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Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease
Published in Blood (08-12-2017)“…Introduction Sickle cell disease (SCD) results from a single mutation in the β-globin gene. Altered erythrocyte physiology in SCD results in severe vascular…”
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PF4-Related Kinocidins Mediate Plasmodicidal Activity of Platelets
Published in Blood (18-11-2011)“…Abstract 1140 Malaria is a thrombocytopenic syndrome. Platelet activation occurs after binding to the knobs of Plasmodium-infected erythrocytes (Srivastava et…”
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PET/CT in lymphoma surveillance: A large single-center experience
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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Severe Acquired Bleeding Tendency Secondary To An Anti-Thrombin Antibody In a Patient With Monoclonal Gammapathy Of Unknown Significance: Direct In Vivo evidence
Published in Blood (15-11-2013)“…Anti-thrombin antibodies are a rare cause of acquired bleeding disorder. We report a case of a patient with a monoclonal gammapathy of unknown significance…”
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