Search Results - "Sharaf Sahar"
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Spontaneous Viral Load Decline and Subsequent Clearance of Chronic Hepatitis C Virus in Postpartum Women Correlates With Favorable Interleukin-28B Gene Allele
Published in Clinical infectious diseases (15-09-2017)“…Background. Postpartum hepatitis C viral (HCV) load decline followed by spontaneous clearance has been previously described. Herein we identify predictors for…”
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Relation of serum levels of homocysteine, vitamin B12 and folate to cognitive functions in multiple sclerosis patients
Published in International journal of neuroscience (02-09-2018)“…Background: Hyperhomocysteinemia, vitamin B12 and folate deficiency have been linked to cognitive dysfunction in multiple sclerosis (MS) patients. Objective:…”
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Investigating the role of VDR gene variants in multiple sclerosis susceptibility: a case–control study in Egypt
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (09-04-2024)“…BackgroundMultiple sclerosis (MS) is a chronic inflammatory disorder. Vitamin D has a major role in preventing inflammatory disorders as well as its role in…”
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Inborn errors of metabolism detectable by tandem mass spectrometry in Egypt: The first newborn screening pilot study
Published in Journal of medical screening (01-09-2016)“…To estimate the burden of metabolic disorders detectable by tandem mass spectrometry in Egypt, through a pilot expanded newborn screening programme at Cairo…”
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Vitamin D receptor gene polymorphisms and idiopathic Parkinson disease: an Egyptian study
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (27-07-2021)“…BackgroundAccumulating data have suggested that vitamin D receptor (VDR) gene is a pretender gene for vulnerability to Parkinson disease (PD). This study aimed…”
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Association of CARD10 rs6000782 and TNF rs1799724 variants with paediatric-onset autoimmune hepatitis
Published in Journal of advanced research (01-01-2019)“…[Display omitted] •CARD10 rs6000782 and TNF rs1799724 SNPs are associated with pAIH.•Carriers of minor alleles of both variants are at a higher risk of…”
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Altered expression of WFS1 and NOTCH2 genes associated with diabetic nephropathy in T2DM patients
Published in Diabetes research and clinical practice (01-06-2018)“…The increased incidence of type 2 diabetes mellitus (T2DM) and the importance of early identification and management of its complications, especially diabetic…”
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Reliability of risk-based screening for hepatitis C virus infection among pregnant women in Egypt
Published in The Journal of infection (01-05-2015)“…Summary Objectives The Centers for Disease Control and Prevention (CDC) only recommends risk-based HCV screening for pregnant women in the United States. This…”
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Vitamin D status in idiopathic Parkinson’s disease: an Egyptian study
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (07-05-2020)“…BackgroundVitamin D is suggested to play an important role in neurodegenerative disorders.ObjectiveTo examine the association between serum 25 vitamin D3 and…”
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Serum level of cytokeratin 19 as a diagnostic and prognostic marker in patients with HCV-related hepatocellular carcinoma
Published in Egyptian Liver Journal (29-06-2021)“…Background The heterogeneous nature of human hepatocellular carcinoma (HCC) impedes both treatment strategies and prognostic predictions. Several markers have…”
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Novel biomarkers for subtle myocardial involvement in type I diabetes mellitus
Published in Cardiovascular endocrinology & metabolism (01-09-2021)“…Background Evaluation of certain biomarkers could be used to predict left ventricular (LV) and right ventricular (RV) function impairment in children with type…”
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Apolipoproteins A1 and B and their ratio in acute ischemic stroke patients with intracranial and extracranial arterial stenosis: an Egyptian study
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (09-12-2020)“…BackgroundApolipoprotein A1 and B and their ratio are considered a better biomarker for cardiovascular diseases than a lipid profile, but this previous finding…”
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Lysosomal Storage Disorders in Egyptian Children
Published in Indian journal of pediatrics (01-08-2016)“…Objective To describe the spectrum, relative prevalence and molecular background of lysosomal storage disorders in Egypt. Methods The authors evaluated the…”
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Brain-derived neurotrophic factor (BDNF) gene polymorphism in a cohort of Egyptian primary open-angle glaucoma (POAG) patients
Published in Bulletin of the National Research Centre (03-04-2020)“…Background Glaucoma is the second leading cause of blindness in the world with primary open-angle glaucoma (POAG) that is the most prevalent type…”
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Identification of insulin gene variants in neonatal diabetes
Published in The journal of maternal-fetal & neonatal medicine (03-05-2017)“…Objectives: Permanent neonatal diabetes (PNDM) is caused by mutations in the genes responsible for the synthesis of different proteins that are important for…”
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Effect of interleukin-10 gene promoter polymorphisms -1082 G/A and -592 C/A on response to therapy in children and adolescents with chronic hepatitis C virus infection
Published in Human immunology (01-12-2016)“…Abstract [Background and Aim] Studying predictors of response to therapy for hepatitis C virus (HCV) infection in children may help avoid the inappropriate use…”
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Hepatitis C Virus (HCV) Vertical Transmission in 12-Month-Old Infants Born to HCV-Infected Women and Assessment of Maternal Risk Factors
Published in Open forum infectious diseases (01-04-2015)“…We summarize the results of HCV RNA testing of 12 month old infants born to HCV infected mothers in Cairo, Egypt. We used real-time PCR testing and…”
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Validation of a Proposed Warfarin Dosing Algorithm Based on the Genetic Make-Up of Egyptian Patients
Published in Molecular diagnosis & therapy (01-12-2013)“…Background Warfarin is the most frequently prescribed oral anticoagulant worldwide. Due to its narrow therapeutic index and inter-patient variability in dose…”
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Association between laboratory markers, clinical and radiological findings in patients with idiopathic intracranial hypertension: case–control study
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (25-09-2024)“…BackgroundIdiopathic intracranial hypertension (IIH) is a disease of raised intracranial pressure. Contribution of inflammatory mediators has been suggested in…”
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