Search Results - "Shapiro, Michael Jeremy"
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The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
Published in eLife (11-11-2021)“…Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are…”
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Journal Article -
2
Histone deacetylase 3 represses cholesterol efflux during CD4 + T-cell activation
Published in eLife (02-12-2021)“…After antigenic activation, quiescent naive CD4 T cells alter their metabolism to proliferate. This metabolic shift increases production of nucleotides, amino…”
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Journal Article -
3
NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors
Published in Frontiers in cell and developmental biology (02-10-2019)“…NKAP is a multi-functional nuclear protein that has been shown to be essential for hematopoiesis. Deletion of NKAP in hematopoietic stem cells (HSCs) was…”
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Journal Article -
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NKAP must associate with HDAC3 to regulate hematopoietic stem cell maintenance and survival1
Published in The Journal of immunology (1950) (25-02-2019)“…NKAP is a multifunctional nuclear protein that associates with the histone deacetylase HDAC3. While both NKAP and HDAC3 are critical for hematopoietic stem…”
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Journal Article -
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NKAP Must Associate with HDAC3 to Regulate Hematopoietic Stem Cell Maintenance and Survival
Published in The Journal of immunology (1950) (15-04-2019)“…NKAP is a multifunctional nuclear protein that associates with the histone deacetylase HDAC3. Although both NKAP and HDAC3 are critical for hematopoietic stem…”
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Journal Article -
6
Histone deacetylase 3 represses cholesterol efflux during CD4.sup.+ T-cell activation
Published in eLife (02-12-2021)“…After antigenic activation, quiescent naive CD4.sup.+ T cells alter their metabolism to proliferate. This metabolic shift increases production of nucleotides,…”
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Journal Article -
7
Role of the Thrombin Receptor's Cytoplasmic Tail in Intracellular Trafficking
Published in The Journal of biological chemistry (20-12-1996)“…The G protein-coupled thrombin receptor is activated by an irreversible proteolytic mechanism and, perhaps as a result, exhibits an unusual trafficking pattern…”
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Journal Article -
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Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization
Published in The Journal of biological chemistry (20-12-1996)“…The G protein-coupled thrombin receptor is activated by an irreversible proteolytic mechanism and, perhaps as a result, exhibits an unusual trafficking pattern…”
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Journal Article -
9
The mechanism of aspartate receptor methylation and its role in bacterial chemotaxis
Published 01-01-1994“…The aspartate receptor from Escherichia coli, which mediates chemotactic behavior, is subject to methylation on four specific glutamate residues. These…”
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Dissertation -
10
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Published in International herald tribune (08-10-2009)Get full text
Newspaper Article -
11
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Published in International herald tribune (08-10-2009)Get full text
Newspaper Article