Search Results - "Shapiro, M. J."

Optimal implantation site for pancreatic islet transplantation by Merani, S., Toso, C., Emamaullee, J., Shapiro, A. M. J.

“…Background: Since the first report of successful pancreatic islet transplantation to reverse hyperglycaemia in diabetic rodents, there has been great interest…”
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role of macrophage migration inhibitory factor on glucose metabolism and diabetes by Toso, C, Emamaullee, J. A, Merani, S, Shapiro, A. M. J

“…Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine involved in many inflammatory reactions and disorders, and it has become evident…”
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One-star rating for a five-star program: evaluating ‘Hospital Compare’ by Shapiro, J.M.

“…For healthcare systems of any size, it is important to minimize costs while maximizing outcomes. One idea of how to achieve these goals has been the reduction…”
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impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells by Bussiere, C. T, Lakey, J. R. T, Shapiro, A. M. J, Korbutt, G. S

“…Aims/hypothesis The Edmonton Protocol for islet transplantation has provided hope for type 1 diabetic patients. However, this protocol requires lifelong…”
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The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function by Dai, X. Q., Manning Fox, J. E., Chikvashvili, D., Casimir, M., Plummer, G., Hajmrle, C., Spigelman, A. F., Kin, T., Singer-Lahat, D., Kang, Y., Shapiro, A. M. J., Gaisano, H. Y., Lotan, I., MacDonald, P. E.

“…Aims/hypothesis It is thought that the voltage-dependent potassium channel subunit Kv2.1 (Kv2.1) regulates insulin secretion by controlling beta cell…”
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Long-Term Follow-Up of the Edmonton Protocol of Islet Transplantation in the United States by Brennan, D.C., Kopetskie, H.A., Sayre, P.H., Alejandro, R., Cagliero, E., Shapiro, A.M.J., Goldstein, J.S., DesMarais, M.R., Booher, S., Bianchine, P.J.

“…We report the long-term follow-up of the efficacy and safety of islet transplantation in seven type 1 diabetic subjects from the United States enrolled in the…”
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Validation of the BETA‐2 Score: An Improved Tool to Estimate Beta Cell Function After Clinical Islet Transplantation Using a Single Fasting Blood Sample by Forbes, S., Oram, R. A., Smith, A., Lam, A., Olateju, T., Imes, S., Malcolm, A. J., Shapiro, A. M. J., Senior, P. A.

“…The beta score, a composite measure of beta cell function after islet transplantation, has limited sensitivity because of its categorical nature and requires a…”
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The Clinical Impact of Islet Transplantation by Fiorina, P., Shapiro, A. M. J., Ricordi, C., Secchi, A.

“…Islet cell transplantation has recently emerged as one of the most promising therapeutic approaches to improving glycometabolic control in diabetic patients…”
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Protease-activated Receptors 1 and 4 Are Shut Off with Distinct Kinetics after Activation by Thrombin by Shapiro, Michael J., Weiss, Ethan J., Faruqi, Tatjana R., Coughlin, Shaun R.

“…Protease-activated receptors 1 and 4 (PAR1 and PAR4) mediate thrombin signaling in human platelets. Whether these receptors are redundant, interact, or serve…”
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Protein NMR-based screening in drug discovery by Zartler, E R, Shapiro, M J

“…Protein NMR as a screening tool in drug discovery has become prominent within the past ten years. Advances in protein manipulation, whether by biological means…”
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Portal Vein Thrombosis Is a Potentially Preventable Complication in Clinical Islet Transplantation by Kawahara, T., Kin, T., Kashkoush, S., Gala‐Lopez, B., Bigam, D. L., Kneteman, N. M., Koh, A., Senior, P. A., Shapiro, A. M. J.

“…Percutaneous transhepatic portal access avoids surgery but is rarely associated with bleeding or portal venous thrombosis (PVT). We herein report our large,…”
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Chemical Basis for Qualitative and Quantitative Differences Between ABO Blood Groups and Subgroups: Implications for Organ Transplantation by Jeyakanthan, M., Tao, K., Zou, L., Meloncelli, P. J., Lowary, T. L., Suzuki, K., Boland, D., Larsen, I., Burch, M., Shaw, N., Beddows, K., Addonizio, L., Zuckerman, W., Afzali, B., Kim, D. H., Mengel, M., Shapiro, A. M. J., West, L. J.

“…Blood group ABH(O) carbohydrate antigens are carried by precursor structures denoted type I–IV chains, creating unique antigen epitopes that may differ in…”
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High Risk of Sensitization After Failed Islet Transplantation by Campbell, P. M., Senior, P. A., Salam, A., LaBranche, K., Bigam, D. L., Kneteman, N. M., Imes, S., Halpin, A., Ryan, E. A., Shapiro, A. M. J.

“…Human Leukocyte Antigen (HLA) antibodies posttransplant have been associated with an increased risk of early graft failure in kidney transplants. Whether this…”
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Engineering Approaches for Understanding Osteogenesis: Hydrogels as Synthetic Bone Microenvironments by Shapiro, J M, Oyen, M L

“…The microenvironment, which can be considered the sum of all the components and conditions surrounding a particular cell, is critical to moderating cellular…”
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The Combination of Anti‐NKG2D and CTLA‐4 Ig Therapy Prolongs Islet Allograft Survival in a Murine Model by Pawlick, R., Gala‐Lopez, B., Pepper, A. R., McCall, M., Ziff, O., Shapiro, A. M. J.

“…Islet transplantation is an effective means of treating severe type 1 diabetes in patients with life‐threatening hypoglycemia. Improvements in glycemic control…”
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The Early Treatment for Retinopathy of Prematurity Clinical Trial: presentation by subgroups versus analysis within subgroups by Hardy, R J, Good, W V, Dobson, V, Palmer, E A, Tung, B, Phelps, D L, Shapiro, M J, van Heuven, W A J

“…The Early Treatment for Retinopathy of Prematurity (ETROP) Study showed that retinal ablation for high-risk prethreshold retinopathy of prematurity (ROP)…”
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Zidovudine-induced fatal lactic acidosis and hepatic failure in patients with acquired immunodeficiency syndrome: Report of two patients and review of the literature by Sundar, Krishnamurthy, Suarez, Miguel, Banogon, Petra E, Shapiro, Janet M

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Liraglutide, a Long-Acting Human Glucagon-Like Peptide 1 Analog, Improves Glucose Homeostasis in Marginal Mass Islet Transplantation in Mice by Merani, S, Truong, W, Emamaullee, J. A, Toso, C, Knudsen, L. B, Shapiro, A. M. J

“…The current scarcity of high-quality deceased pancreas donors prevents widespread application of islet transplantation for treatment of labile type 1 diabetes…”
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Is there a daily discount rate? Evidence from the food stamp nutrition cycle by Shapiro, Jesse M.

“…Quasi-hyperbolic discounting predicts impatience over short-run tradeoffs. I present a direct non-laboratory test of this implication using data on the…”
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Autologous Islet Transplantation After Total Pancreatectomy for Renal Cell Carcinoma Metastases by Gala‐Lopez, B. L., Semlacher, E., Manouchehri, N., Kin, T., Shapiro, A. M. J.

“…Pancreatic metastases from renal cell carcinoma (RCC) may have a chronic and highly indolent course, and may be resected for cure after considerable delay…”
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