Search Results - "Shapiro, E. G."

Control of a High-Speed Channel Spectrum Using an Off-Center Signal Chirp by Shapiro, E. G., Shapiro, D. A.

“…A method is proposed for transferring the spectrum of an optical signal from the vicinity of one carrier frequency to the vicinity of another using an…”
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Phase-Modulated Format of Off-Center Chirped Data Transmission over a High-Speed Optical Link without Dispersion Compensation by Shapiro, E. G., Shapiro, D. A.

“…We consider a communication line without dispersion compensation. A new type of a phase-modulated format is proposed, in which Gaussian pulses with a varying…”
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Combination of enzyme replacement and hematopoietic stem cell transplantation as therapy for Hurler syndrome by Tolar, J, Grewal, S S, Bjoraker, K J, Whitley, C B, Shapiro, E G, Charnas, L, Orchard, P J

“…Hurler syndrome (mucopolysaccharidosis type I, MPS IH) is characterized by a deficiency of α- L -iduronidase resulting in progressive multiorgan dysfunction…”
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Long-term metabolic, endocrine, and neuropsychological outcome of hematopoietic cell transplantation for Wolman disease by Tolar, J, Petryk, A, Khan, K, Bjoraker, K J, Jessurun, J, Dolan, M, Kivisto, T, Charnas, L, Shapiro, E G, Orchard, P J

“…Wolman disease is the infantile form of autosomal recessive acid lipase deficiency, typically presenting in early infancy with diarrhea, massive…”
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N-acetyl-L-cysteine improves outcome of advanced cerebral adrenoleukodystrophy by TOLAR, J, ORCHARD, P. J, BJORAKER, K. J, ZIEGLER, R. S, SHAPIRO, E. G, CHARNAS, L

“…Hematopoietic stem cell transplantation as a treatment for childhood cerebral adrenoleukodystrophy (ALD) has historically only been successful in early…”
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Neuropsychological outcomes of several storage diseases with and without bone marrow transplantation by Shapiro, E. G., Lockman, L. A., Balthazor, M., Krivit, W.

“…Summary Neuropsychological assessment is essential in providing documentation of the untreated natural history of storage diseases associated with dementia and…”
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Nonlinear Noise Statistics in a High-Speed Optical Communication Line without Dispersion Compensation by Shapiro, E. G., Shapiro, D. A.

“…— The communication line without compensation of dispersion is considered. It is shown analytically and numerically that the field power in the fiber on almost…”
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Hematopoietic Stem-Cell Transplantation in Globoid-Cell Leukodystrophy by Krivit, William, Shapiro, Elsa G, Peters, Charles, Wagner, John E, Cornu, Guy, Kurtzberg, Joanne, Wenger, David A, Kolodny, Edwin H, Vanier, Marie T, Loes, Daniel J, Dusenbery, Kathryn, Lockman, Lawrence A

“…Globoid-cell leukodystrophy is an autosomal recessive disease due to greatly diminished or absent activity of the lysosomal enzyme galactocerebrosidase. 1 The…”
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Assessment of adrenoleukodystrophy lesions by high field MRS in non-sedated pediatric patients by TKAC, I, CHARNAS, L. R, CHOI, I. Y, BJORAKER, K. J, SHAPIRO, E. G, GRUETTER, R

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The future for treatment by bone marrow transplantation for adrenoleukodystrophy, metachromatic leukodystrophy, globoid cell leukodystrophy and Hurler syndrome by Krivit, W., Lockman, L. A., Watkins, P. A., Hirsch, J., Shapiro, E. G.

“…Summary Within the past decade, bone marrow transplantation has been applied to over 200 patients worldwide with the intention of treating storage diseases…”
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Method for computing the optimal signal distribution and channel capacity by Shapiro, E G, Shapiro, D A, Turitsyn, S K

“…An iterative method for computing the channel capacity of both discrete and continuous input, continuous output channels is proposed. The efficiency of new…”
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Outcome of Unrelated Donor Bone Marrow Transplantation in 40 Children With Hurler Syndrome by Peters, Charles, Balthazor, Michael, Shapiro, Elsa G., King, Roberta J., Kollman, Craig, Hegland, Janet D., Henslee-Downey, Jean, Trigg, Michael E., Cowan, Morton J., Sanders, Jean, Bunin, Nancy, Weinstein, Howard, Lenarsky, Carl, Falk, Peter, Harris, Richard, Bowen, Tom, Williams, Thomas E., Grayson, Guy H., Warkentin, Phyllis, Sender, Leonard, Cool, Valerie A., Crittenden, Mary, Packman, Seymour, Kaplan, Paige, Lockman, Lawrence A., Anderson, James, Krivit, William, Dusenbery, Kathryn, Wagner, John

“…Long-term survival and improved neuropsychological function have occurred in selected children with Hurler syndrome (MPS I H) after successful engraftment with…”
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The nature and impact of neurobehavioral symptoms in neuronopathic Hunter syndrome by Eisengart, J.B., King, K.E., Shapiro, E.G., Whitley, C.B., Muenzer, J.

“…In neuronopathic Hunter syndrome, neurobehavioral symptoms are known to be serious but have been incompletely described. While families face significant stress…”
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Outcome of second hematopoietic cell transplantation in Hurler syndrome by GREWAL, S. S, KRIVIT, W, DEFOR, T. E, SHAPIRO, E. G, ORCHARD, P. J, ABEL, S. L, LOCKMAN, L. A, ZIEGLER, R. S, DUSENBERY, K. E, PETERS, C

“…Hurler syndrome (HS) is an autosomal recessive, inherited metabolic storage disorder due to deficiency of lysosomal alpha-L-iduronidase (IDU) enzyme activity…”
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Imperfect narrow filtering in optical links with phase modulation by Shapiro, E.G., Shapiro, D.A.

“…In order to reveal the pattern effect in the optical signal transmission it is studied as a random complex process. The different sources of detection error…”
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Reduction of nonlinear intrachannel effects by channel asymmetry in transmission lines with strong bit overlapping by Shapiro, E.G., Fedoruk, M.P., Turitsyn, S.K., Shafarenko, A.

“…We have examined the statistics of simulated bit-error rates in optical transmission systems with strong patterning effects and have found strong correlation…”
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Hurler syndrome: Past, present, and future by Peters, Charles, Shapiro, Elsa G., Krivit, William

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Long-Term Cognitive and Functional Outcomes in Children with Mucopolysaccharidosis (MPS)-IH (Hurler Syndrome) Treated with Hematopoietic Cell Transplantation by Kunin-Batson, A. S., Shapiro, E. G., Rudser, K. D., Lavery, C. A., Bjoraker, K. J., Jones, S. A., Wynn, R. F., Vellodi, A., Tolar, J., Orchard, P. J., Wraith, J. E.

“…The long-term cognitive and functional outcomes of children with mucopolysaccharidosis type I (MPS-IH) post-hematopoietic cell transplant (HCT) are not well…”
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Proton MR spectroscopy and neuropsychological testing in adrenoleukodystrophy by Rajanayagam, V, Balthazor, M, Shapiro, EG, Krivit, W, Lockman, L, Stillman, AE

“…To determine early signs of disease in patients with childhood-onset cerebral adrenoleukodystrophy (COCALD) with the use of proton MR spectroscopy. Eleven…”
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Research challenges in central nervous system manifestations of inborn errors of metabolism by Dickson, P.I., Pariser, A.R., Groft, S.C., Ishihara, R.W., McNeil, D.E., Tagle, D., Griebel, D.J., Kaler, S.G., Mink, J.W., Shapiro, E.G., Bjoraker, K.J., Krivitzky, L., Provenzale, J.M., Gropman, A., Orchard, P., Raymond, G., Cohen, B.H., Steiner, R.D., Goldkind, S.F., Nelson, R.M., Kakkis, E., Patterson, M.C.

“…The Research Challenges in CNS Manifestations of Inborn Errors of Metabolism workshop was designed to address challenges in translating potential therapies for…”
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