Search Results - "Shaoliang Peng"
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MultiDTI: drug–target interaction prediction based on multi-modal representation learning to bridge the gap between new chemical entities and known heterogeneous network
Published in Bioinformatics (07-12-2021)“…Abstract Motivation Predicting new drug–target interactions is an important step in new drug development, understanding of its side effects and drug…”
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A hybrid two-stage financial stock forecasting algorithm based on clustering and ensemble learning
Published in Applied intelligence (Dordrecht, Netherlands) (01-11-2020)“…This paper investigates the problem of the stock closing price forecasting for the stock market. Based on existing two-stage fusion models in the literature,…”
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Joint consensus and diversity for multi-view semi-supervised classification
Published in Machine learning (01-03-2020)“…As data can be acquired in an ever-increasing number of ways, multi-view data is becoming more and more available. Considering the high price of labeling data…”
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Improving prediction performance of general protein language model by domain-adaptive pretraining on DNA-binding protein
Published in Nature communications (07-09-2024)“…DNA-protein interactions exert the fundamental structure of many pivotal biological processes, such as DNA replication, transcription, and gene regulation…”
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A Review of Blockchain-Based Secure Sharing of Healthcare Data
Published in Applied sciences (01-08-2022)“…Medical data contains multiple records of patient data that are important for subsequent treatment and future research. However, it needs to be stored and…”
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Machine Learning Applications in Drug Repurposing
Published in Interdisciplinary sciences : computational life sciences (01-03-2022)“…The coronavirus disease (COVID-19) has led to an rush to repurpose existing drugs, although the underlying evidence base is of variable quality. Drug…”
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NeRD: a multichannel neural network to predict cellular response of drugs by integrating multidimensional data
Published in BMC medicine (17-10-2022)“…Background Considering the heterogeneity of tumors, it is a key issue in precision medicine to predict the drug response of each individual. The accumulation…”
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SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler
Published in Gigascience (27-12-2012)“…There is a rapidly increasing amount of de novo genome assembly using next-generation sequencing (NGS) short reads; however, several big challenges remain to…”
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OffScan: a universal and fast CRISPR off-target sites detection tool
Published in BMC genomics (05-03-2020)“…The Type II clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) is a powerful genome editing technology,…”
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Cotton D genome assemblies built with long-read data unveil mechanisms of centromere evolution and stress tolerance divergence
Published in BMC biology (03-06-2021)“…Many of genome features which could help unravel the often complex post-speciation evolution of closely related species are obscured because of their location…”
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CRISP-view: a database of functional genetic screens spanning multiple phenotypes
Published in Nucleic acids research (08-01-2021)“…Abstract High-throughput genetic screening based on CRISPR/Cas9 or RNA-interference (RNAi) enables the exploration of genes associated with the phenotype of…”
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The Integrative Method Based on the Module-Network for Identifying Driver Genes in Cancer Subtypes
Published in Molecules (Basel, Switzerland) (24-01-2018)“…With advances in next-generation sequencing(NGS) technologies, a large number of multiple types of high-throughput genomics data are available. A great…”
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Performance Improvement of Atmospheric Continuous-Variable Quantum Key Distribution with Untrusted Source
Published in Entropy (Basel, Switzerland) (16-06-2021)“…Atmospheric continuous-variable quantum key distribution (ACVQKD) has been proven to be secure theoretically with the assumption that the signal source is well…”
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14
Interface structure and work function of W-Cu interfaces
Published in Applied physics letters (18-11-2013)“…First principles calculation reveals that W-Cu interfaces have high interface strength when the number of overlayers is less than 2, and that (111)Cu/(110)W…”
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IMGPU: GPU-Accelerated Influence Maximization in Large-Scale Social Networks
Published in IEEE transactions on parallel and distributed systems (01-01-2014)“…Influence Maximization aims to find the top-(K) influential individuals to maximize the influence spread within a social network, which remains an important…”
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MHGTMDA: Molecular heterogeneous graph transformer based on biological entity graph for miRNA-disease associations prediction
Published in Molecular therapy. Nucleic acids (12-03-2024)“…MicroRNAs (miRNAs) play a crucial role in the prevention, prognosis, diagnosis, and treatment of complex diseases. Existing computational methods primarily…”
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VISPR-online: a web-based interactive tool to visualize CRISPR screening experiments
Published in BMC bioinformatics (24-06-2021)“…VISPR is an interactive visualization and analysis framework for CRISPR screening experiments. However, it only supports the output of MAGeCK, and requires…”
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SOAP3-dp: fast, accurate and sensitive GPU-based short read aligner
Published in PloS one (31-05-2013)“…To tackle the exponentially increasing throughput of Next-Generation Sequencing (NGS), most of the existing short-read aligners can be configured to favor…”
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cmFSM: a scalable CPU-MIC coordinated drug-finding tool by frequent subgraph mining
Published in BMC bioinformatics (08-05-2018)“…Frequent subgraphs mining is a significant problem in many practical domains. The solution of this kind of problem can particularly used in some large-scale…”
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A Radiomics Signature to Quantitatively Analyze COVID-19-Infected Pulmonary Lesions
Published in Interdisciplinary sciences : computational life sciences (01-03-2021)“…Assessing pulmonary lesions using computed tomography (CT) images is of great significance to the severity diagnosis and treatment of coronavirus disease 2019…”
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