Search Results - "Shao, Xinli"

Smad2 Protects against TGF-β/Smad3-Mediated Renal Fibrosis by XIAO MING MENG, XIAO RU HUANG, CHUNG, Arthur C. K, WEI QIN, XINLI SHAO, IGARASHI, Peter, WENJUN JU, BOTTINGER, Erwin P, HUI YAO LAN

“…Smad2 and Smad3 interact and mediate TGF-beta signaling. Although Smad3 promotes fibrosis, the role of Smad2 in fibrogenesis is largely unknown. In this study,…”
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Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia by Patel, Vishal, Li, Ling, Cobo-Stark, Patricia, Shao, Xinli, Somlo, Stefan, Lin, Fangming, Igarashi, Peter

“…Polycystic kidney disease (PKD) is an inherited disorder that is characterized by the accumulation of cysts in the renal parenchyma and progressive decline in…”
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Metabolic, Reproductive, and Neurologic Abnormalities in Agpat1-Null Mice by Agarwal, Anil K, Tunison, Katie, Dalal, Jasbir S, Nagamma, Sneha S, Hamra, F Kent, Sankella, Shireesha, Shao, Xinli, Auchus, Richard J, Garg, Abhimanyu

“…Defects in the biosynthesis of phospholipids and neutral lipids are associated with cell membrane dysfunction, disrupted energy metabolism, and diseases…”
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Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract by XINLI SHAO, SOMLO, Stefan, IGARASHI, Peter

“…Ksp-cadherin is a unique, tissue-specific member of the cadherin family of cell adhesion molecules that is expressed in tubular epithelial cells in the kidney…”
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Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy by Cortés, Víctor A., Curtis, David E., Sukumaran, Suja, Shao, Xinli, Parameswara, Vinay, Rashid, Shirya, Smith, Amy R., Ren, Jimin, Esser, Victoria, Hammer, Robert E., Agarwal, Anil K., Horton, Jay D., Garg, Abhimanyu

“…Mutations in 1-acylglycerol-3-phosphate-O-acyltransferase 2 ( AGPAT2) cause congenital generalized lipodystrophy. To understand the molecular mechanisms…”
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A transcriptional network in polycystic kidney disease by Gresh, Lionel, Fischer, Evelyne, Reimann, Andreas, Tanguy, Myriam, Garbay, Serge, Shao, Xinli, Hiesberger, Thomas, Fiette, Laurence, Igarashi, Peter, Yaniv, Moshe, Pontoglio, Marco

“…Mutations in cystic kidney disease genes represent a major genetic cause of end‐stage renal disease. However, the molecular cascades controlling the expression…”
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Roles of HNF-1β in kidney development and congenital cystic diseases by Igarashi, Peter, Shao, Xinli, Mcnally, Brian T., Hiesberger, Thomas

“…Roles of HNF-1β in kidney development and congenital cystic diseases. Hepatocyte nuclear factor-1β (HNF-1β) is a Pit-1/Oct-1/Unc-86…”
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Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney by Pao, Alan C, Bhargava, Aditi, Di Sole, Francesca, Quigley, Raymond, Shao, Xinli, Wang, Jian, Thomas, Sheela, Zhang, Jianning, Shi, Mingjun, Funder, John W, Moe, Orson W, Pearce, David

“…Serum and glucocorticoid-regulated kinase 2 (sgk2) is 80% identical to the kinase domain of sgk1, an important mediator of mineralocorticoid-regulated sodium…”
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A minimal ksp-cadherin promoter linked to a green fluorescent protein reporter gene exhibits tissue-specific expression in the developing kidney and genitourinary tract by SHAD, Xinli, JOHNSON, Jane E, RICHARDSON, James A, HIESBERGER, Thomas, IGARASHI, Peter

“…Ksp-cadherin is a unique, tissue-specific member of the cadherin family of cell adhesion molecules that is expressed exclusively in tubular epithelial cells in…”
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Excitotoxicity of TNFa derived from KA activated microglia on hippocampal neurons in vitro and in vivo by Zhu, Wei, Zheng, Honghua, Shao, Xinli, Wang, Wei, Yao, Qing, Li, Zhengli

“…J. Neurochem. (2010) 114, 386-396.AbstractHighly activated microglia and followed excessive expression of inflammatory cytokines are associated with…”
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Bisulfite-Containing Propofol: Is it a Cost-Effective Alternative to Diprivan™ for Induction of Anesthesia? by Shao, Xinli, Li, Hong, White, Paul F., Klein, Kevin W., Kulstad, Christine, Owens, Andrew

“…Propofol (Diprivan(TM); AstraZeneca, Wilmington, DE) is a commonly used drug for the induction of general anesthesia in the ambulatory setting. With the…”
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Excitotoxicity of TNFα derived from KA activated microglia on hippocampal neurons in vitro and in vivo by Zhu, Wei, Zheng, Honghua, Shao, Xinli, Wang, Wei, Yao, Qing, Li, Zhengli

“…J. Neurochem. (2010) 114, 386-396. Highly activated microglia and followed excessive expression of inflammatory cytokines are associated with neuroexcitotoxic…”
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Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter by Williams, Scott S, Cobo-Stark, Patricia, Hajarnis, Sachin, Aboudehen, Karam, Shao, Xinli, Richardson, James A, Patel, Vishal, Igarashi, Peter

“…Autosomal recessive polycystic kidney disease, an inherited disorder characterized by the formation of cysts in renal collecting ducts and biliary dysgenesis,…”
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Mutation of hepatocyte nuclear factor–1β inhibits Pkhd1 gene expression and produces renal cysts in mice by Hiesberger, Thomas, Bai, Yun, Shao, Xinli, McNally, Brian T., Sinclair, Angus M., Tian, Xin, Somlo, Stefan, Igarashi, Peter

“…Hepatocyte nuclear factor-1 beta (HNF-1 beta ) is a Pit-1, Oct-1/2, UNC-86 (POU)/homeodomain-containing transcription factor that regulates tissue-specific…”
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Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis by Shao, Xinli, Yang, Ru, Yan, Mei, Li, Yajuan, Du, Yong, Raman, Indu, Zhang, Bo, Wakeland, Ward, Igarashi, Peter, Mohan, Chandra, Li, Quan‐Zhen

“…Objective To ascertain whether engineered expression of kallikreins within the kidneys, using an inducible Cre/loxP system, can ameliorate murine lupus…”
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Oxidation resistance protein 1 (Oxr1) protects against autoantibody-induced glomerulonephritis by inhibiting inflammation and apoptosis (56.10) by Li, Yajuan, Shao, Xinli, Raman, Indu, Yan, Mei, Du, Yong, Mohan, Chandra, Li, Quanzhen

“…Abstract Oxidative stress is a common pathologic feature of immune-mediated nephritis in both human and mouse model. However, the molecular pathways that…”
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Role of the Hepatocyte Nuclear Factor-1β (HNF-1β) C-terminal Domain in Pkhd1 (ARPKD) Gene Transcription and Renal Cystogenesis by Hiesberger, Thomas, Shao, Xinli, Gourley, Eric, Reimann, Andreas, Pontoglio, Marco, Igarashi, Peter

“…Hepatocyte nuclear factor-1β (HNF-1β) is a homeodomain-containing transcription factor that regulates tissue-specific gene expression in the kidney and other…”
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Error in Author Name in Article by Shao et al (Arthritis Rheum, March 2013) by Shao, Xinli, Yan, Ru Yang Mei, Li, Yajuan, Du, Yong, Raman, Indu, Zhang, Bo, Wakeland, Ward, Igarashi, Peter, Mohan, Chandra, Li, Quan-Zhen

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Inducible expression of kallikrein in kidney tubular cells protected mice from spontaneous lupus nephritis (107.8) by Li, Quanzhen, Shao, Xinli, Yang, Ru, Li, Yajuan, Xie, Shangkui, Mohan, Chandra, Igarashi, Peter

“…Abstract Inducible gene modification using the Cre/loxP system provides a valuable tool for analysis of gene function in specific tissues of live animals. To…”
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Kallikrein gene modified mesenchymal stem cell transplantation protected mice from anti-GBM induced and lupus nephritis (107.10) by Li, Quanzhen, Li, Yajuan, Shao, Xinli, Ramin, Indu, Yan, Mei, Min, So, Du, Yong, Mohan, Chandra

“…Abstract Mesenchymal stem cells (MSC) have been reported to be an attractive cell source for treatment of renal diseases. Recently, we reported that…”
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