Search Results - "Shao, Ruoyang"
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ATXN2L upregulated by epidermal growth factor promotes gastric cancer cell invasiveness and oxaliplatin resistance
Published in Cell death & disease (20-02-2019)“…For gastric cancer (GC) control, metastasis and chemoresistance are the major challenges, accompanied with various stresses. Ataxin-2-like (ATXN2L) was…”
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2
Engineering macrophages to phagocytose cancer cells by blocking the CD47/SIRPɑ axis
Published in Cancer medicine (Malden, MA) (01-08-2019)“…The use of immunotherapy has achieved great advances in the treatment of cancer. Macrophages play a pivotal role in the immune defense system, serving both as…”
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Venetoclax Combined with Azacitidine and Homoharringtonine in Relapsed/Refractory AML: A Multicenter, Phase 2 Trial
Published in Journal of hematology and oncology (29-04-2023)“…Relapsed or refractory acute myeloid leukemia (R/R AML) has a dismal prognosis. The aim of this study was to investigate the activity and tolerability of…”
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4
Cell-cell contact-induced gene editing/activation in mammalian cells using a synNotch-CRISPR/Cas9 system
Published in Protein & cell (01-04-2020)Get full text
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Hepatic venous pressure gradient-guided laparoscopic splenectomy and pericardial devascularisation versus endoscopic therapy for secondary prophylaxis for variceal rebleeding in portal hypertension (CHESS1803): study protocol of a multicenter randomised controlled trial in China
Published in BMJ open (23-06-2020)“…IntroductionGastro-oesophageal variceal bleeding is one of the most common and severe complications with high mortality in cirrhotic patients who developed…”
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Impact of genetic patterns on sorafenib efficacy in patients with FLT3-ITD acute myeloid leukemia undergoing allogeneic hematopoietic stem cell transplantation: a multi-center, cohort study
Published in Signal transduction and targeted therapy (14-09-2023)“…Sorafenib therapy improves overall survival (OS) in patients with FLT3 internal tandem duplication (ITD) acute myeloid leukemia (AML) undergoing allogeneic…”
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The Presence of Ascites Affects the Predictive Value of HVPG on Early Rebleeding in Patients with Cirrhosis
Published in Gastroenterology research and practice (2020)“…Background and Aims. Gastroesophageal variceal bleeding is a serious complication of portal hypertension in cirrhotic patients and could be predicted by…”
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Mesenchymal Stromal Cell Infusion Might Improve Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation and Modulate Alveolar Macrophages in Mice
Published in Blood (02-11-2023)“…Some studies suggested that mesenchymal stromal cell (MSC) infusion might improve bronchiolitis obliterans (BO) in patients who received allogeneic…”
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Impact of Concomitant Genetic Abnormalities on Sorafenib Therapy in FLT3-ITD Positive Acute Myeloid Leukemia Undergoing Allo-HSCT
Published in Blood (23-11-2021)“…Aim In this study, we investigated the co-occurring mutation landscape in acute myeloid leukemia (AML) patients with FLT3 internal tandem duplication…”
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Sorafenib Plus Triplet Therapy with Venetoclax, Azacitibine and Homoharringtonine for Refractory/Relapsed Acute Myeloid Leukemia with FLT3-ITD: A Multicentre, Phase 2 Study
Published in Blood (02-11-2023)“…Abstract Background Patients with relapsed or refractory acute myeloid leukemia (R/R AML) with FLT3 internal tandem duplication (FLT3-ITD) have an infrequent…”
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11
Comprehensive pan-cancer analysis of KLRB1-CLEC2D pair and identification of small molecule inhibitors to disrupt their interaction
Published in International immunopharmacology (25-10-2024)“…•Higher CLEC2D/KLRB1 ratio is observed in most cancers compared to normal tissues.•CLEC2D and KLRB1 expression variation is mainly due to lymphocyte…”
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Comment on “Somatostatin as Inflow Modulator in Liver-transplant Recipients With Severe Portal Hypertension: A Randomized Trial”
Published in Annals of surgery (01-08-2021)Get full text
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13
Genetic characteristics predict response to venetoclax plus hypomethylating agents in relapsed or refractory acute myeloid leukemia
Published in Journal of internal medicine (01-03-2023)“…Background The heterogeneity of relapsed or refractory (R/R) acute myeloid leukemia (AML) leads to no response to venetoclax (VEN)–based therapy in more than…”
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Nestin+ Mesenchymal Stromal Cells Fibrotic Transition Mediated by CD169+ Macrophages in Bone Marrow Chronic Graft-versus-Host Disease
Published in The Journal of immunology (1950) (01-10-2023)“…Abstract Chronic graft-versus-host disease (cGVHD) involves multiple organs, but little is known about bone marrow (BM) alterations caused by cGVHD. In mice…”
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15
Ruxolitinib versus basiliximab for steroid-refractory acute graft-versus-host disease: a retrospective study
Published in Annals of hematology (01-10-2023)“…Acute graft-versus-host disease (aGVHD) remains a major limitation of allogeneic hematopoietic stem cell transplantation; not all patients respond to standard…”
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Sorafenib plus triplet therapy with venetoclax, azacitidine and homoharringtonine for refractory/relapsed acute myeloid leukemia with FLT3‐ITD: A multicenter phase 2 study
Published in Journal of internal medicine (01-02-2024)“…Background Patients with relapsed or refractory acute myeloid leukemia (R/R AML) and FLT3‐internal tandem duplication (FLT3‐ITD) respond infrequently to…”
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Sorafenib maintenance after allogeneic haemopoietic stem-cell transplantation in patients with FLT3-ITD acute myeloid leukaemia: long-term follow-up of an open-label, multicentre, randomised, phase 3 trial
Published in The Lancet. Haematology (01-08-2023)“…Our open-label, multicentre, randomised, phase 3 trial showed that sorafenib maintenance after haematopoietic stem-cell transplantation (HSCT) improved overall…”
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18
Prognostic impact of mutations on acute myeloid leukemia
Published in Therapeutic advances in hematology (01-09-2024)“…Background: Interleukin-7 receptor ( IL7R ) mutation has been demonstrated to be an adverse prognostic factor in acute lymphoblastic leukemia (ALL) patients…”
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PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production
Published in Annals of translational medicine (01-02-2020)“…Neoadjuvant radiotherapy is a commonly used method for the current standard-of-care for most patients with rectal cancer, when the effects of radioresistance…”
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Prognostic impact of IL7R mutations on acute myeloid leukemia
Published in Therapeutic advances in hematology (01-01-2024)“…Interleukin-7 receptor ( ) mutation has been demonstrated to be an adverse prognostic factor in acute lymphoblastic leukemia (ALL) patients. However, the…”
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