Search Results - "Shao, Matt X G"
-
1
Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium
Published in American journal of physiology. Lung cellular and molecular physiology (01-06-2008)“…Toll-like receptors (TLRs) are critical for the recognition of inhaled pathogens that deposit on the airway epithelial surface. The epithelial response to…”
Get more information
Journal Article -
2
Dual Oxidase 1-Dependent MUC5AC Mucin Expression in Cultured Human Airway Epithelial Cells
Published in Proceedings of the National Academy of Sciences - PNAS (18-01-2005)“…Mucus hypersecretion is a prominent manifestation in patients with chronic inflammatory airway diseases. MUC5AC mucin is a major component of airway mucus, and…”
Get full text
Journal Article -
3
Pseudomonas Lipopolysaccharide Accelerates Wound Repair via Activation of a Novel Epithelial Cell Signaling Cascade
Published in Journal of Immunology (15-12-2006)“…The surface of the airway epithelium represents a battleground in which the host intercepts signals from pathogens and activates epithelial defenses to combat…”
Get full text
Journal Article -
4
Regulation of interleukin-8 via an airway epithelial signaling cascade
Published in American journal of physiology. Lung cellular and molecular physiology (01-05-2007)“…Airways function as an innate immune organ against airborne bacteria that are inhaled and deposited in airways. One of the mechanisms of host defense is to…”
Get more information
Journal Article -
5
Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-converting enzyme
Published in The Journal of immunology (1950) (15-09-2005)“…Mucus hypersecretion is a prominent manifestation in patients with chronic inflammatory airway diseases and contributes to their morbidity and mortality by…”
Get full text
Journal Article -
6
Tumor Necrosis Factor α-Converting Enzyme Mediates MUC5AC Mucin Expression in Cultured Human Airway Epithelial Cells
Published in Proceedings of the National Academy of Sciences - PNAS (30-09-2003)“…Ectodomain shedding of epidermal growth factor receptor (EGFR) ligands [e.g., transforming growth factor type α(TGF-α)] and EGFR phosphorylation are implicated…”
Get full text
Journal Article -
7
Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells
Published in American journal of physiology. Lung cellular and molecular physiology (01-08-2004)“…Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in the U.S. Because cigarette smoking is so importantly implicated in the…”
Get more information
Journal Article -
8
Lipopolysaccharide Initiates a Positive Feedback of Epidermal Growth Factor Receptor Signaling by Prostaglandin E2 in Human Biliary Carcinoma Cells
Published in The Journal of immunology (1950) (15-02-2009)“…Bacterial products (e.g., LPS) are viewed as critical stimuli in inflammation-associated cancer. Cyclooxygenase 2 (COX-2), a major effector of LPS, and EGFR,…”
Get full text
Journal Article -
9