Search Results - "Shao, Matt X G"

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  1. 1

    Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium by Koff, Jonathan L, Shao, Matt X G, Ueki, Iris F, Nadel, Jay A

    “…Toll-like receptors (TLRs) are critical for the recognition of inhaled pathogens that deposit on the airway epithelial surface. The epithelial response to…”
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    Journal Article
  2. 2

    Dual Oxidase 1-Dependent MUC5AC Mucin Expression in Cultured Human Airway Epithelial Cells by Matt X. G. Shao, Nadel, Jay A., Clements, John A.

    “…Mucus hypersecretion is a prominent manifestation in patients with chronic inflammatory airway diseases. MUC5AC mucin is a major component of airway mucus, and…”
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  3. 3

    Pseudomonas Lipopolysaccharide Accelerates Wound Repair via Activation of a Novel Epithelial Cell Signaling Cascade by Koff, Jonathan L, Shao, Matt X. G, Kim, Suil, Ueki, Iris F, Nadel, Jay A

    Published in Journal of Immunology (15-12-2006)
    “…The surface of the airway epithelium represents a battleground in which the host intercepts signals from pathogens and activates epithelial defenses to combat…”
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  4. 4

    Regulation of interleukin-8 via an airway epithelial signaling cascade by Nakanaga, Takashi, Nadel, Jay A, Ueki, Iris F, Koff, Jonathan L, Shao, Matt X G

    “…Airways function as an innate immune organ against airborne bacteria that are inhaled and deposited in airways. One of the mechanisms of host defense is to…”
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  5. 5

    Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-converting enzyme by Shao, Matt X G, Nadel, Jay A

    Published in The Journal of immunology (1950) (15-09-2005)
    “…Mucus hypersecretion is a prominent manifestation in patients with chronic inflammatory airway diseases and contributes to their morbidity and mortality by…”
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    Journal Article
  6. 6

    Tumor Necrosis Factor α-Converting Enzyme Mediates MUC5AC Mucin Expression in Cultured Human Airway Epithelial Cells by Matt X. G. Shao, Ueki, Iris F., Nadel, Jay A.

    “…Ectodomain shedding of epidermal growth factor receptor (EGFR) ligands [e.g., transforming growth factor type α(TGF-α)] and EGFR phosphorylation are implicated…”
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  7. 7

    Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells by Shao, Matt X G, Nakanaga, Takashi, Nadel, Jay A

    “…Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in the U.S. Because cigarette smoking is so importantly implicated in the…”
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  8. 8

    Lipopolysaccharide Initiates a Positive Feedback of Epidermal Growth Factor Receptor Signaling by Prostaglandin E2 in Human Biliary Carcinoma Cells by Finzi, Laetitia, Shao, Matt X. G, Paye, Francois, Housset, Chantal, Nadel, Jay A

    Published in The Journal of immunology (1950) (15-02-2009)
    “…Bacterial products (e.g., LPS) are viewed as critical stimuli in inflammation-associated cancer. Cyclooxygenase 2 (COX-2), a major effector of LPS, and EGFR,…”
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