Search Results - "Shao, Hongzhao"

Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective by Ahmed, Alveena, Boulton, Stephen, Shao, Hongzhao, Akimoto, Madoka, Natarajan, Amarnath, Cheng, Xiaodong, Melacini, Giuseppe

“…The universal second messenger cAMP regulates diverse intracellular processes by interacting with ubiquitously expressed proteins, such as Protein Kinase A…”
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Reversible DNA–Protein Cross‐Linking at Epigenetic DNA Marks by Ji, Shaofei, Shao, Hongzhao, Han, Qiyuan, Seiler, Christopher L., Tretyakova, Natalia Y.

“…5‐Formylcytosine (5fC) is an endogenous DNA modification frequently found within regulatory elements of mammalian genes. Although 5fC is an oxidation product…”
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5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in human cells by Ji, Shaofei, Fu, Iwen, Naldiga, Spandana, Shao, Hongzhao, Basu, Ashis K, Broyde, Suse, Tretyakova, Natalia Y

“…Abstract 5-Formylcytosine (5fC) is an epigenetic DNA modification introduced via TET protein-mediated oxidation of 5-methyl-dC. We recently reported that 5fC…”
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CHESPA/CHESCA-SPARKY: automated NMR data analysis plugins for SPARKY to map protein allostery by Shao, Hongzhao, Boulton, Stephen, Olivieri, Cristina, Mohamed, Hebatallah, Akimoto, Madoka, Subrahmanian, Manu Veliparambil, Veglia, Gianluigi, Markley, John L, Melacini, Giuseppe, Lee, Woonghee

“…Abstract Motivation Correlated Nuclear Magnetic Resonance (NMR) chemical shift changes identified through the CHEmical Shift Projection Analysis (CHESPA) and…”
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Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist by Shao, Hongzhao, Mohamed, Hebatallah, Boulton, Stephen, Huang, Jinfeng, Wang, Pingyuan, Chen, Haiying, Zhou, Jia, Luchowska-Stańska, Urszula, Jentsch, Nicholas G, Armstrong, Alison L, Magolan, Jakob, Yarwood, Stephen, Melacini, Giuseppe

“…The exchange protein activated by cAMP (EPAC) is a promising drug target for a wide disease range, from neurodegeneration and infections to cancer and…”
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QSAR models reveal new EPAC-selective allosteric modulators by Mohamed, Hebatallah, Shao, Hongzhao, Akimoto, Madoka, Darveau, Patrick, MacKinnon, Marc R, Magolan, Jakob, Melacini, Giuseppe

“…Exchange proteins directly activated by cAMP (EPAC) are guanine nucleotide exchange factors for the small GTPases, Rap1 and Rap2. They regulate several…”
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5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in human cells by Ji, Shaofei, Fu, Iwen, Naldiga, Spandana, Shao, Hongzhao, Basu, Ashis K, Broyde, Suse, Tretyakova, Natalia Y

“…Nucleic Acids Research, 46(13):6455–6469, https://doi.org/10.1093/nar/gky444. There was a typographical error on page 6458, column 1, line 12 and on page 6459,…”
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Corrigendum: 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in human cells by Ji, Shaofei, Fu, Iwen, Naldiga, Spandana, Shao, Hongzhao, Basu, Ashis K, Broyde, Suse, Tretyakova, Natalia Y

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Reversible DNA–Protein Cross‐Linking at Epigenetic DNA Marks by Ji, Shaofei, Shao, Hongzhao, Han, Qiyuan, Seiler, Christopher L., Tretyakova, Natalia Y.

“…5‐Formylcytosine (5fC) is an endogenous DNA modification frequently found within regulatory elements of mammalian genes. Although 5fC is an oxidation product…”
Get full text