Search Results - "Shanmuganathan, Somya"

Abstract P2-03-19: Discovery of the genes that underpin the transition to malignant phenotype of breast tumors in highly consanguineous region by Gupta, Ishita, Ouhtit, Allal, Shanmuganathan, Somya, Al-Riyami, Hamad

“…Breast cancer (BC), a multifactorial and heterogeneous disease is a predominant women form of cancer worldwide affecting 22.9%. The rationale of this study is…”
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Abstract 1257: From chemoprevention strategy to identification of potential therapeutic targets and biomarkers for breast cancer by Ouhtit, Allal, Shanmuganathan, Somya, Gupta, Ishita, Al-Riyami, Hamad, Raj, Madhwa

“…Over the years, several phyto-compounds have been extensively used in Complementary Alternative Medicine (CAM) studies, individually and often at higher doses…”
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Chemoprevention of Rat Mammary Carcinogenesis by Spirulina by Ouhtit, Allal, Ismail, Mohammed F, Othman, Amira, Fernando, Augusta, Abdraboh, Mohamed E, El-Kott, Attalla F, Azab, Yahia A, Abdeen, Sherif H, Gaur, Rajiv L, Gupta, Ishita, Shanmuganathan, Somya, Al-Farsi, Yahya M, Al-Riyami, Hamad, Raj, Madhwa H.G

“…Spirulina (SP) ( Arthrospira platensis ; previously Spirulina platensis ) is a filamentous blue-green microalga (cyanobacterium) with potent dietary…”
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Understanding the functional discrepancy of Pim-1 in cancer by Ouhtit, Allal, Muzumdar, Sukalp, Gupta, Ishita, Shanmuganathan, Somya, Tamimi, Yahya

“…The Pim-1 gene encodes for a proto-oncogenic serine/threonine protein kinase and is generally involved in cytokine signaling as well as in various signaling…”
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Hoxb13, a potential prognostic biomarker for prostate cancer by Ouhtit, Allal, Al-Kindi, Mohammed N, Kumar, Parvathy R, Gupta, Ishita, Shanmuganathan, Somya, Tamimi, Yahya

“…HOXB13, a member of the homeobox proteins family, is a key regulator of the epithelial differentiation in the prostate gland. HOXB13 is overexpressed during…”
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Abstract A72: TGF-β2 underpins CD44-promoted breast tumor cell invasion by Ouhtit, Allal, Madani, Samineh, Gupta, Ishita, Shanmuganathan, Somya, Al-Riyami, Hamad, Al-Farsi, Yahya

“…Hyaluronan (HA) mediates communication between cancer cells and the environment via interactions with the cell surface receptor CD44. The long-term objective…”
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Abstract 3302: CD146, a suppressor of breast cancer, is a novel target of CD44-signaling by Abdraboh, Mohamed E., Al-Riyami, Hamad, Al-Farsi, Yahya, Ouhtit, Allal, Hollenbach, Andrew D., Gupta, Ishita, Shanmuganathan, Somya, Raj, Madhwa H.

“…More than 80% of cancer related deaths are caused by cancer cell metastasis, a crucial step in the onset of tumor development. Among the molecules involved in…”
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Abstract 2806: CD146, a suppressor of breast cancer, is a novel target of CD44-signaling by Ouhtit, Allal, Abdraboh, Mohamed E., Hollenbach, Andrew D., Gupta, Ishita, Shanmuganathan, Somya, Raj, Madhwa HG

“…Cancer cell invasion and metastasis is the worst aspect of cancer, and disruption in the cell adhesion molecules (CAM) represents the initiating event in tumor…”
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Simultaneous inhibition of cell-cycle, proliferation, survival, metastatic pathways and induction of apoptosis in breast cancer cells by a phytochemical super-cocktail: genes that underpin its mode of action by Ouhtit, Allal, Gaur, Rajiv Lochan, Abdraboh, Mohamed, Ireland, Shubha K, Rao, Prakash N, Raj, Shailaja G, Al-Riyami, Hamad, Shanmuganathan, Somya, Gupta, Ishita, Murthy, Subramanyam N, Hollenbach, Andrew, Raj, Madhwa Hg

“…Traditional chemotherapy and radiotherapy for cancer treatment face serious challenges such as drug resistance and toxic side effects. Complementary /…”
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Abstract 4384: Discovery of CD146/Latexin as a novel pathway suppressing breast tumor invasion by Ouhtit, Allal, Abd Elmageed, Zakariya Y., Fernando, Augusta, Gaur, Rajiv, Gupta, Ishita, Shanmuganathan, Somya, Al-Riyami, Hamad, Raj, Madhwa HG

“…CD146, also known as melanoma cell adhesion molecule or MUC18, was initially identified as a promoter of melanoma as well as prostate cancer progression and…”
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Abstract A71: CD146 is a novel target of CD44-signaling mediating breast tumor invasion by Ouhtit, Allal, Abdraboh, Mohamed, Hollenbach, Andrew D., Gupta, Ishita, Shanmuganathan, Somya, Riyami, Hamad Al, Errami, Youssef, Farsi, Yahya Al, Raj, Madhwa HG

“…Cancer cell metastasis is one of the most critical steps in tumor development and is responsible for more than 80% of cancer related deaths. The cell adhesion…”
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Abstract A73: In vivo evidence of TIMPv as a potential target of CD146-signaling inhibiting breast tumor invasion by Ouhtit, Allal, Elmageed, Zakariya Y. Abd, Bhat, Sunil, Raman, Pravrutha, Al-Jardani, Suad H., Gupta, Ishita, Shanmuganathan, Somya, Al-Riyami, Hamad

“…CD146, also known as melanoma cell adhesion molecule (Mel-CAM, MCAM) or MUC18, was initially identified as a marker of melanoma progression and a promoter of…”
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TGF-β2: A Novel Target of CD44-Promoted Breast Cancer Invasion by Ouhtit, Allal, Madani, Samineh, Gupta, Ishita, Shanmuganathan, Somya, Abdraboh, Mohamed E, Al-Riyami, Hamad, Al-Farsi, Yahya M, Raj, Madhwa Hg

“…We have developed a tetracycline (tet)-off regulated expression of CD44s gene in the breast cancer (BC) cell line MCF-7 (B5 clone) and identified TGF-β2…”
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