Search Results - "Shanks, Julia"

Angiotensin II and the Cardiac Parasympathetic Nervous System in Hypertension by Shanks, Julia, Ramchandra, Rohit

“…The renin-angiotensin-aldosterone system (RAAS) impacts cardiovascular homeostasis via direct actions on peripheral blood vessels and via modulation of the…”
Get full text

Peripheral cardiac sympathetic hyperactivity in cardiovascular disease: role of neuropeptides by Shanks, Julia, Herring, Neil

“…High levels of sympathetic drive in several cardiovascular diseases including postmyocardial infarction, chronic congestive heart failure and hypertension are…”
Get more information

Regulation of Coronary Blood Flow by the Carotid Body Chemoreceptors in Ovine Heart Failure by Pachen, Mridula, Abukar, Yonis, Shanks, Julia, Lever, Nigel, Ramchandra, Rohit

“…Carotid bodies (CBs) are peripheral chemoreceptors, which are primary sensors of systemic hypoxia and their activation produces respiratory, autonomic, and…”
Get full text

Cardiac sympathetic dysfunction in the prehypertensive spontaneously hypertensive rat by Shanks, Julia, Manou-Stathopoulou, Sotiria, Lu, Chieh-Ju, Li, Dan, Paterson, David J, Herring, Neil

“…Recent studies in prehypertensive spontaneously hypertensive rats (SHR) have shown larger calcium transients and reduced norepinephrine transporter (NET)…”
Get more information

TRPV1 (Transient Receptor Potential Vanilloid 1) Cardiac Spinal Afferents Contribute to Hypertension in Spontaneous Hypertensive Rat by Shanks, Julia, de Morais, Sharon D.B, Gao, Lie, Zucker, Irving H, Wang, Han-Jun

“…Hypertension is associated with increased sympathetic activity. A component of this sympathoexcitation may be driven by increased signaling from sensory…”
Get full text

Ganglion-Specific Impairment of the Norepinephrine Transporter in the Hypertensive Rat by Shanks, Julia, Mane, Saras, Ryan, Rebecca, Paterson, David J

“…Hypertension is associated with enhanced cardiac sympathetic transmission, although the exact mechanisms underlying this are still unknown. We hypothesized…”
Get full text

The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: Implications for neural control of cardiac excitability by Herring, Neil, Cranley, James, Lokale, Michael N, Li, Dan, Shanks, Julia, Alston, Eric N, Girard, Beatrice M, Carter, Emma, Parsons, Rodney L, Habecker, Beth A, Paterson, David J

“…Abstract The autonomic phenotype of congestive cardiac failure is characterised by high sympathetic drive and impaired vagal tone, which are independent…”
Get full text

Dynamic monitoring of NET activity in mature murine sympathetic terminals using a fluorescent substrate by Parker, Lauren K, Shanks, Julia A, Kennard, James AG, Brain, Keith L

“…Background and purpose:  To validate a fluorescence approach for monitoring norepinephrine transporter (NET) transport rate in mature sympathetic terminals,…”
Get full text

A Healthy Dose of Mischief by Shanks, Julia

“…An obituary for Hershel Shanks, the founder and editor emeritus of the Biblical Archaeology Review who died on February 5, 2021 at 90-years-old, is presented…”
Get full text

Tag team or buddy system: How do co-transmitters modulate autonomic responses? by Gimhani, Dilsha, Aikeremu, Nigala, Shanks, Julia

Get full text

Neural control of coronary artery blood flow by non-adrenergic and non-cholinergic mechanisms by Shanks, Julia, Thomson, Stian, Ramchandra, Rohit

“…What is the topic of this review? How non-adrenergic, non-cholinergic neural mechanisms regulate coronary artery blood flow. What advances does it highlight?…”
Get full text

How Important Is SERCA In Neuronal Calcium Homeostasis? by Shanks, Julia, Paterson, David

“…Abstract only Maintaining intracellular calcium homeostasis is critical for excitation‐contraction coupling in the heart, and is essentially dependent on…”
Get full text

Activation of the carotid body increases directly recorded cardiac sympathetic nerve activity and coronary blood flow in conscious sheep by Pachen, Mridula, Abukar, Yonis, Shanks, Julia, Lever, Nigel, Ramchandra, Rohit

“…Activation of the carotid body (CB) using intracarotid potassium cyanide (KCN) injection increases coronary blood flow (CoBF). This increase in CoBF is…”
Get more information

Altered autonomic control or coronary artery blood flow by the aortic body chemoreceptors in conscious normotensive and hypertensive sheep by Shanks, Julia, Pen, Dylan, Abukar, Yonis, Ramchandra, Rohit

“…Abstract only Peripheral arterial chemoreceptors monitor the chemical composition of the blood. While, the carotid bodies located at the bifurcation of the…”
Get full text

Sympathomodulation in heart failure: A role for stellate ganglia Nrf2 by Shanks, Julia, Gao, Lie, Zucker, Irving H.

“…Nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) is a key transcription factor involved in modulating redox signalling by regulating the expression of a…”
Get full text

Developing a Large Animal Model of Heart Failure with Preserved Ejection Fraction by Hamilton, Charlotte, George, Bindu, Shanks, Julia, Ramchandra, Rohit

“…Objective Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome representing more than 50% of heart failure cases. Currently, available…”
Get full text

Effect of high nasal flow on blood flow in an ovine model of renovascular hypertension by Pachen, Mridula, Shanks, Julia, Abukar, Yonis, Ramchandra, Rohit

“…Our present study examined the effects of heated, humidified, high nasal flow air therapy (HNF) in an ovine model of renovascular hypertension. HNF is commonly…”
Get full text

Cardiac Vagal Nerve Activity Increases During Exercise to Enhance Coronary Blood Flow by Shanks, Julia, Pachen, Mridula, Chang, Joshua W-H., George, Bindu, Ramchandra, Rohit

“…BACKGROUND: The phrase complete vagal withdrawal is often used when discussing autonomic control of the heart during exercise. However, more recent studies…”
Get full text

Redistribution of blood flow during exercise is impaired in heart failure with preserved ejection fraction by Ramchandra, Rohit, Hamilton, Charlotte, Shanks, Julia, Pachen, Mridula, Chang, Joshua, Chen, Siyi

“…Abstract only Exercise intolerance is a cardinal symptom in heart failure with preserved ejection fraction (HFpEF). The underlying pathophysiological…”
Get full text

Aortic Body Chemoreceptors Regulate Coronary Blood Flow in Conscious Control and Hypertensive Sheep by Pen, Dylan, Shanks, Julia, Barrett, Carolyn, Abukar, Yonis, Paton, Julian F.R., Ramchandra, Rohit

Get full text