Search Results - "Shanks, J.V."

Effect of elicitor dosage and exposure time on biosynthesis of indole alkaloids by Catharanthus roseus hairy root cultures by Rijhwani, S.K, Shanks, J.V

“…Late exponential phase hairy root cultures of Catharanthus roseus were elicited with pectinase and jasmonic acid. The effects of elicitor concentration and…”
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Confirmation of Conjugation Processes during TNT Metabolism by Axenic Plant Roots by Bhadra, R, Wayment, D. G, Hughes, J. B, Shanks, J. V

“…This paper examines processes in plants for the formation of fate products of TNT beyond its aminated reduction products, 2-amino-4,6-dinitrotoluene and…”
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Characterization of an Ethanol-Inducible Promoter System in Catharanthus roseus Hairy Roots by Peebles, C.A.M, Gibson, S.I, Shanks, J.V, San, K.Y

“…Efforts to engineer Catharanthus roseus hairy roots to produce commercially significant amounts of valuable compounds, such as the terpenoid indole alkaloids…”
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TNT phytotransformation pathway characteristics of Arabidopsis: role of aromatic hydroxylamines by Subramanian, M, Oliver, D.J, Shanks, J.V

“…Basic knowledge of the plant transformation pathways of TNT will aid phytoremediation design and assessment. While TNT transformation by plant metabolism has…”
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Characterization of Oxidation Products of TNT Metabolism in Aquatic Phytoremediation Systems of Myriophyllum aquaticum by Bhadra, R, Spanggord, R. J, Wayment, D. G, Hughes, J. B, Shanks, J. V

“…TNT transformation processes in sediment-free, “natural”, aquatic phytoremediation systems of Myriophyllum aquaticum were investigated with specific interest…”
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Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots by Hong, S.B, Hughes, E.H, Shanks, J.V, San, K.Y, Gibson, S.I

“…The 1‐deoxy‐d‐xylulose‐5‐phosphate (DXP) pathway (non‐mevalonate pathway) leading to terpenoids via isopentenyl diphosphate (IPP) has been shown to occur in…”
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Phytotransformation of trinitrotoluene (TNT) and distribution of metabolic products in Myriophyllum aquaticum by Vanderford, M, Shanks, J.V, Hughes, J.B

“…Dissolved [U-ring-14C]2,4,6-trinitrotoluene, when exposed to Myriophyllum aquaticum plants, was transformed with approximately 30% of products recovered in the…”
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Expression of the Arabidopsis feedback-insensitive anthranilate synthase holoenzyme and tryptophan decarboxylase genes in Catharanthus roseus hairy roots by Hong, Seung-Beom, Peebles, Christie A.M., Shanks, Jacqueline V., San, Ka-Yiu, Gibson, Susan I.

“…In plants, the indole pathway provides precursors for a variety of secondary metabolites. In Catharanthus roseus, a decarboxylated derivative of tryptophan,…”
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Expression of a feedback-resistant anthranilate synthase in Catharanthus roseus hairy roots provides evidence for tight regulation of terpenoid indole alkaloid levels by Hughes, E.H, Hong, S.B, Gibson, S.I, Shanks, J.V, San, K.Y

“…Different plant species produce a variety of terpenoid indole alkaloids, which are of interest as plant defensive secondary metabolites and as valuable…”
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Phytotoxicity and phytoremediation of 2,6-dinitrotoluene using a model plant, Arabidopsis thaliana by Yoon, Jong Moon, Oliver, David J., Shanks, Jacqueline V.

“…Biochemical and genetic studies of xenobiotic metabolism in the model plant Arabidopsis have significant potential in providing information for…”
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Determination of metabolic rate-limitations by precursor feeding in Catharanthus roseus hairy root cultures by Morgan, J.A, Shanks, J.V

“…Precursors from the terpenoid and tryptophan branches were fed to Catharanthus roseus to determine which of the two branches limits metabolic flux to indole…”
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Metabolic Engineering of Plants for Alkaloid Production by Hughes, Erik H., Shanks, Jacqueline V.

“…Alkaloids purified from plants provide many pharmacologically active compounds, including leading chemotherapy drugs. As is generally true of secondary…”
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Terpenoid indole alkaloid production by Catharanthus roseus hairy roots induced by Agrobacterium tumefaciens harboring rol ABC genes by Hong, S.B, Peebles, C.A.M, Shanks, J.V, San, K.Y, Gibson, S.I

“…We have established Catharanthus roseus hairy root cultures transgenic for the rol ABC genes from T(L)-DNA of the agropine-type Agrobacterium rhizogenes strain…”
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Effects of terpenoid precursor feeding on Catharanthus roseus hairy roots over-expressing the alpha or the alpha and beta subunits of anthranilate synthase by Peebles, C.A.M, Hong, S.B, Gibson, S.I, Shanks, J.V, San, K.Y

“…Among the pharmacologically important terpenoid indole alkaloids produced by Catharanthus roseus are the anti-cancer drugs vinblastine and vincristine. These…”
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Flux quantification in central carbon metabolism of Catharanthus roseus hairy roots by 13C labeling and comprehensive bondomer balancing by Sriram, Ganesh, Fulton, D. Bruce, Shanks, Jacqueline V.

“…Metabolic flux quantification is a powerful profiling tool in plant metabolic engineering and systems biology. We introduce the application of “bondomers”, a…”
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Long-Term Maintenance of a Transgenic Catharanthus roseus Hairy Root Line by Peebles, C.A.M, Gibson, S.I, Shanks, J.V, San, K.Y

“…Stably transformed transgenic hairy root cultures have the potential to be a valuable production platform for a variety of secondary metabolites. This study…”
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Transient effects of overexpressing anthranilate synthase α and β subunits in Catharanthus roseus hairy roots by Peebles, C.A.M, Hong, S.B, Gibson, S.I, Shanks, J.V, San, K.Y

“…Catharanthus roseus produces two economically valuable anticancer drugs, vinblastine and vincristine. These drugs are members of the terpenoid indole alkaloids…”
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Enhanced transformation of TNT by tobacco plants expressing a bacterial nitroreductase by Hannink, N.K, Subramanian, M, Rosser, S.J, Basran, A, Murray, J.A.H, Shanks, J.V, Bruce, N.C

“…The manufacture, disposal, and detonation of explosives have resulted in the pollution of large tracts of land and groundwater. Historically,…”
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Studies on plant-mediated fate of the explosives RDX and HMX by Bhadra, R., Wayment, D.G., Williams, R.K., Barman, S.N., Stone, M.B., Hughes, J.B., Shanks, J.V.

“…The fate of the explosives RDX and HMX on exposure to plants was investigated in ‘natural’ aquatic systems of Myriophyllum aquaticum for 16 days, and in axenic…”
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Phytotransformation of 2,4-Dinitrotoluene in Arabidopsis thaliana: Toxicity, Fate, and Gene Expression Studies in Vitro by Yoon, J.M, Oliver, D.J, Shanks, J.V

“…Basic knowledge of the plant transformation pathways and toxicity of 2,4-dinitrotoluene (2,4-DNT) will assist in the design and assessment of a…”
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