Search Results - "Shankar, Raakhee"
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Regulated lipid synthesis and LEM2/CHMP7 jointly control nuclear envelope closure
Published in The Journal of cell biology (04-05-2020)“…The nuclear permeability barrier depends on closure of nuclear envelope (NE) holes. Here, we investigate closure of the NE opening surrounding the meiotic…”
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Journal Article -
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The Sar1 GTPase is dispensable for COPII-dependent cargo export from the ER
Published in Cell reports (Cambridge) (27-06-2023)“…Coat protein complex II (COPII) plays an integral role in the packaging of secretory cargoes within membrane-enclosed transport carriers that leave the…”
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Journal Article -
3
Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
Published in Nature communications (13-11-2017)“…Degradation of most integral membrane proteins is directed by the endosomal sorting complex required for transport (ESCRT) machinery, which selectively targets…”
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Journal Article -
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Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans
Published in Genetics (Austin) (01-09-2019)“…cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and…”
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Journal Article -
5
The receptor protein tyrosine phosphatase CLR-1 is required for synaptic partner recognition
Published in PLoS genetics (09-05-2018)“…During neural circuit formation, most axons are guided to complex environments, coming into contact with multiple potential synaptic partners. However, it is…”
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Journal Article -
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Growth factor stimulation promotes multivesicular endosome biogenesis by prolonging recruitment of the late-acting ESCRT machinery
Published in Proceedings of the National Academy of Sciences - PNAS (02-04-2019)“…The formation of multivesicular endosomes (MVEs) mediates the turnover of numerous integral membrane proteins and has been implicated in the down-regulation of…”
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Journal Article -
7
The ESCRT machinery directs quality control over inner nuclear membrane architecture
Published in Cell reports (Cambridge) (18-01-2022)“…The late-acting endosomal sorting complex required for transport (ESCRT) machinery has been implicated in facilitating the resealing of the nuclear envelope…”
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Journal Article -
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Regulation of Nuclear Envelope Remodeling by the ESCRT Machinery
Published 01-01-2021“…The endosomal sorting complex required for transport (ESCRT) machinery participates in a wide range of cellular processes. These processes include…”
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Dissertation -
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Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans
Published in Genetics (Austin) (01-09-2019)“…cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and…”
Get full text
Journal Article -
10
Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans
Published in Genetics (Austin) (01-09-2019)“…cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and…”
Get full text
Journal Article