Search Results - "Shangguan, Chengfang"
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LncRNA HCP5 Participates in the Tregs Functions in Allergic Rhinitis and Drives Airway Mucosal Inflammatory Response in the Nasal Epithelial Cells
Published in Inflammation (01-06-2022)“…Allergic rhinitis (AR) is an allergic disease characterized as (immunoglobulin, IgE)-mediated type I hypersensitivity disorder. Regulatory T cells (Tregs) play…”
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Intrinsic RIG-I restrains STAT5 activation to modulate antitumor activity of CD8+ T cells
Published in The Journal of clinical investigation (01-05-2023)“…Antitumor activity of CD8+ T cells is potentially restrained by a variety of negative regulatory pathways that are triggered in the tumor microenvironment,…”
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Cancer-associated fibroblasts enhance tumor 18F-FDG uptake and contribute to the intratumor heterogeneity of PET-CT
Published in Theranostics (01-01-2018)“…Purpose: Elevated glucose uptake is a hallmark of cancer. Fluorodeoxyglucose (FDG) uptake was believed to indicate the aggressiveness of tumors and the…”
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Performance of 18F-FDG PET/CT Radiomics for Predicting EGFR Mutation Status in Patients With Non-Small Cell Lung Cancer
Published in Frontiers in oncology (08-10-2020)“…OBJECTIVETo assess the performance of pretreatment 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) radiomics features…”
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Molecular evolutionary process of advanced gastric cancer during sequential chemotherapy detected by circulating tumor DNA
Published in Journal of translational medicine (12-08-2022)“…Abstract Background Efficacy of conventional sequential chemotherapy paradigm for advanced gastric cancer (AGC) patients has largely plateaued. Dynamic…”
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Prognostic value of clinicopathological characteristics in patients with pancreatic cancer
Published in Chinese journal of cancer research (01-10-2015)“…Background: The purpose of this study was to analyze the effects of all clinical characteristics on the overall survival time, in order to provide a basis for…”
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Value of 68Ga-FAPI-04 and 18F-FDG PET/CT in Early Prediction of Pathologic Response to Neoadjuvant Chemotherapy in Locally Advanced Gastric Cancer
Published in The Journal of nuclear medicine (1978) (01-02-2024)“…This prospective study investigated whether PET parameters from 18F-FDG and 68Ga-fibroblast activation protein inhibitor (FAPI)-04 PET/CT can predict a…”
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68Ga-FAPI-04 Positron Emission Tomography Distinguishes Malignancy From 18F-FDG-Avid Colorectal Lesions
Published in International journal of radiation oncology, biology, physics (01-01-2024)“…PURPOSELesions with a high uptake of 18F-fluorodeoxyglucose (18F-FDG) on positron emission tomography-computed tomography (PET-CT) can be benign and malignant…”
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Utility of [68Ga]FAPI-04 and [18F]FDG dual-tracer PET/CT in the initial evaluation of gastric cancer
Published in European radiology (01-06-2023)“…Objectives We aimed to investigate the role of [ 68 Ga]FAPI-04 and [ 18 F]FDG dual-tracer PET/CT for the initial assessment of gastric cancer and to explore…”
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Anlotinib plus chemotherapy as first-line therapy for patients with gastrointestinal tumor with unresectable liver metastasis: Results from a multi-cohort, multicenter phase II trial (ALTER-G-001)
Published in Journal of clinical oncology (01-06-2023)“…e16268 Background: Patients (pts) with advanced gastrointestinal (GI) tumors, such as colorectal cancer (CRC), esophageal squamous cell carcinoma (ESCC),…”
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Intrinsic RIG-I restrains STAT5 activation to modulate antitumor activity of [CD8.sup.+] T cells
Published in The Journal of clinical investigation (01-05-2023)“…Antitumor activity of [CD8.sup.+] T cells is potentially restrained by a variety of negative regulatory pathways that are triggered in the tumor…”
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Modulation of lipid metabolism associated with response to metronomic capecitabine plus camrelizumab in patients with refractory gastrointestinal cancer: A prospective, single-center, exploratory trial
Published in Journal of clinical oncology (01-06-2024)“…2616 Background: Metronomic chemotherapy which can modulate tumor microenvironment is a potential partner of PD-1 antibodies. The association between lipid…”
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Anlotinib plus chemotherapy as first-line therapy for patients with gastrointestinal tumor with unresectable liver metastasis: Updated results from a multi-cohort, multi-center phase II trial, ALTER-G-001-cohort C
Published in Journal of clinical oncology (01-06-2024)“…e16304 Background: Advanced gastrointestinal (GI) tumors, such as colorectal, gastric and pancreatic cancers (CRC, GC, and PC), and esophageal squamous cell…”
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Anlotinib plus chemotherapy as first-line therapy for patients with gastrointestinal tumor with unresectable liver metastasis: Updated results from a multi-cohort, multi-center phase II trial ALTER-G-001-cohort C
Published in Journal of clinical oncology (20-01-2024)“…653 Background: Advanced gastrointestinal (GI) tumors, such as colorectal, gastric and pancreatic cancers (CRC, GC, and PC), and esophageal squamous cell…”
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A phase Ib, open-label, multi-cohort study of metronomic capecitabine plus camrelizumab for treatment of refractory solid tumor: McCrest trial
Published in Journal of clinical oncology (01-06-2022)“…e16079 Background: The efficacy of immune checkpoint inhibitors (ICIs) monotherapy for refractory solid tumor is relatively poor. Combination therapy is an…”
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Optimizing the program of sequential chemotherapy for advanced gastric cancer based on gene-level CNVs called from ctDNA
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e16068 Background: Tumor evolutionary trade-offs under treatment pressure can be utilized to optimize therapy. We aimed to profile the dynamic…”
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The efficacy of pyrotinib-based therapy in lapatinib-resistant metastatic HER2-positive breast cancer
Published in Annals of palliative medicine (01-01-2022)Get full text
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The kynurenine derivative 3-HAA sensitizes hepatocellular carcinoma to sorafenib by upregulating phosphatases
Published in Theranostics (01-01-2021)“…: Sorafenib is the only FDA-approved first-line target drug for HCC patients. However, sorafenib merely confers 3-5 months of survival benefit with less than…”
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Anlotinib plus chemotherapy as first-line therapy for gastrointestinal tumor patients with unresectable liver metastasis: A multicenter, multicohort clinical trial (ALTER-G-001)
Published in Journal of clinical oncology (01-02-2022)“…Abstract only TPS229 Background: Liver metastases (LMs) are usually found in gastrointestinal tumors, such as colorectal cancer (mCRC), esophageal squamous…”
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