Search Results - "Shang, Helen H"
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Functional regions of the peroxin Pex19 necessary for peroxisome biogenesis
Published in The Journal of biological chemistry (07-07-2017)“…The peroxins Pex19 and Pex3 play an indispensable role in peroxisomal membrane protein (PMP) biogenesis, peroxisome division, and inheritance. Pex19 plays…”
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Journal Article -
2
Feeding intolerance in critically ill patients with COVID-19
Published in Clinical nutrition (Edinburgh, Scotland) (01-12-2022)“…Early reports suggest significant difficulty with enteral feeding in critically ill COVID-19 patients. This study aimed to characterize the prevalence,…”
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Journal Article -
3
DICER1 mutations in primary central nervous system tumors: new insights into histologies, mutations, and prognosis
Published in Journal of neuro-oncology (01-05-2022)“…Purpose We sought to characterize clinical outcomes for adult and pediatric patients with primary CNS tumors harboring DICER1 mutations or loss of DICER1 …”
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Clinically Relevant Latent Space Embedding of Cancer Histopathology Slides Through Variational Autoencoder based Image Compression
Published in 2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI) (18-04-2023)“…In this paper, we introduce a Variational Autoencoder (VAE) based training approach that can compress and decompress cancer pathology slides at a compression…”
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Conference Proceeding -
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A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels
Published in 2023 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB) (29-08-2023)“…Histopathological work in clinical labs often relies on immunostaining of proteins, which can be time-consuming and costly. Multiplexed spatial proteomics…”
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Conference Proceeding -
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The state of applying artificial intelligence to tissue imaging for cancer research and early detection [version 1; peer review: awaiting peer review]
Published in F1000 research (2023)“…Artificial intelligence (AI) represents a new frontier in human medicine that could save more lives and reduce the costs, thereby increasing accessibility. As…”
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SpatialVisVR: An Immersive, Multiplexed Medical Image Viewer with Contextual Similar-Patient Search
Published in 2024 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB) (27-08-2024)“…In contemporary pathology, multiplexed immunofluorescence (mIF) and multiplex immunohistochemistry (mIHC) present both significant opportunities and…”
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Conference Proceeding -
8
SpatialVisVR: An Immersive, Multiplexed Medical Image Viewer With Contextual Similar-Patient Search
Published 05-01-2024“…In contemporary pathology, multiplexed immunofluorescence (mIF) and multiplex immunohistochemistry (mIHC) present both significant opportunities and…”
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Journal Article -
9
Peptide Sequencing Via Protein Language Models
Published 01-08-2024“…We introduce a protein language model for determining the complete sequence of a peptide based on measurement of a limited set of amino acids. To date, protein…”
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Multimodal Pathology Image Search Between H&E Slides and Multiplexed Immunofluorescent Images
Published 11-06-2023“…We present an approach for multimodal pathology image search, using dynamic time warping (DTW) on Variational Autoencoder (VAE) latent space that is fed into a…”
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Clinically Relevant Latent Space Embedding of Cancer Histopathology Slides through Variational Autoencoder Based Image Compression
Published 23-03-2023“…2023 IEEE ISBI, Cartagena, Colombia, 2023, pp. 1-5 In this paper, we introduce a Variational Autoencoder (VAE) based training approach that can compress and…”
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12
Histopathology Slide Indexing and Search: Are We There Yet?
Published 29-06-2023“…The search and retrieval of digital histopathology slides is an important task that has yet to be solved. In this case study, we investigate the clinical…”
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Journal Article -
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The State of Applying Artificial Intelligence to Tissue Imaging for Cancer Research and Early Detection
Published 29-06-2023“…F1000Research 2023, 12:1436 Artificial intelligence represents a new frontier in human medicine that could save more lives and reduce the costs, thereby…”
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14
Real-Time Diagnostic Integrity Meets Efficiency: A Novel Platform-Agnostic Architecture for Physiological Signal Compression
Published 19-12-2023“…Head-based signals such as EEG, EMG, EOG, and ECG collected by wearable systems will play a pivotal role in clinical diagnosis, monitoring, and treatment of…”
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Journal Article