Search Results - "Shane, M."
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1
The anterior thalamic nuclei: core components of a tripartite episodic memory system
Published in Nature reviews. Neuroscience (01-08-2022)“…Standard models of episodic memory focus on hippocampal–parahippocampal interactions, with the neocortex supplying sensory information and providing a final…”
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2
Mitotic progression following DNA damage enables pattern recognition within micronuclei
Published in Nature (London) (24-08-2017)“…The authors report a link between mitosis, the formation of micronuclei and DNA-damage-induced cGAS-dependent inflammation. Cell cycle effects of combined…”
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3
Hippocampal-anterior thalamic pathways for memory: uncovering a network of direct and indirect actions
Published in The European journal of neuroscience (01-06-2010)“…This review charts recent advances from a variety of disciplines that create a new perspective on why the multiple hippocampal–anterior thalamic…”
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4
Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress
Published in Molecular psychiatry (01-09-2021)“…Chronic stress contributes to the development of psychiatric disorders including anxiety and depression. Several inflammatory-related effects of stress are…”
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5
Precision wildlife monitoring using unmanned aerial vehicles
Published in Scientific reports (17-03-2016)“…Unmanned aerial vehicles (UAVs) represent a new frontier in environmental research. Their use has the potential to revolutionise the field if they prove…”
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Identification of a nematic pair density wave state in Bi2Sr2CaCu2O8+x
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2022)“…Electron-pair density wave (PDW) states are now an intense focus of research in the field of cuprate correlated superconductivity. PDWs exhibit periodically…”
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7
Quadratic Response Properties from TDDFT: Trials and Tribulations
Published in Journal of chemical theory and computation (13-02-2018)“…We report on the efficient turbomole implementation of quadratic response properties within the time-dependent density functional theory (TDDFT) context that…”
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Digital postprocessing and image segmentation for objective analysis of colorimetric reactions
Published in Nature protocols (01-01-2021)“…Recently, there has been an explosion of scientific literature describing the use of colorimetry for monitoring the progression or the endpoint result of…”
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9
Protein digestibility-corrected amino acid scores and digestible indispensable amino acid scores differentially describe protein quality in growing male rats
Published in The Journal of nutrition (01-02-2015)“…The FAO has recommended replacing the protein digestibility-corrected amino acid score (PDCAAS) with the digestible indispensable amino acid score (DIAAS). The…”
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10
Regulation of the MIR155 host gene in physiological and pathological processes
Published in Gene (10-12-2013)“…MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by acting as adaptors for the…”
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Methodology for Determining Degree of Hydrolysis of Proteins in Hydrolysates: A Review
Published in Journal of AOAC International (01-09-2010)“…Degree of hydrolysis (DH) is defined as the proportion of cleaved peptide bonds in a protein hydrolysate. Several methods exist for determining DH; the most…”
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12
ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition
Published in Cell reports (Cambridge) (13-10-2015)“…Resolution of DNA double-strand breaks (DSBs) is essential for the suppression of genome instability. DSB repair in transcriptionally active genomic regions…”
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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Published in Molecular cell (09-01-2014)“…MRE11 within the MRE11-RAD50-NBS1 (MRN) complex acts in DNA double-strand break repair (DSBR), detection, and signaling; yet, how its endo- and exonuclease…”
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14
Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge
Published in Acta neuropathologica communications (26-11-2018)“…Microglia are the resident innate immune cells of the central nervous system. Limited turnover throughout the lifespan leaves microglia susceptible to…”
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Inflammation as a central mechanism in Alzheimer's disease
Published in Alzheimer's & dementia : translational research & clinical interventions (2018)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized by cognitive decline and the presence of two core pathologies,…”
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16
Converging Time-Dependent Density Functional Theory Calculations in Five Iterations with Minimal Auxiliary Preconditioning
Published in Journal of chemical theory and computation (13-08-2024)“…Eigenvalue problems and linear systems of equations involving large symmetric matrices are commonly solved in quantum chemistry using Krylov space methods,…”
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17
On the electron pairing mechanism of copper-oxide high temperature superconductivity
Published in Proceedings of the National Academy of Sciences - PNAS (13-09-2022)“…The elementary CuO 2 plane sustaining cuprate high-temperature superconductivity occurs typically at the base of a periodic array of edge-sharing CuO 5…”
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Traumatic Brain Injury Causes Chronic Cortical Inflammation and Neuronal Dysfunction Mediated by Microglia
Published in The Journal of neuroscience (17-02-2021)“…Traumatic brain injury (TBI) can lead to significant neuropsychiatric problems and neurodegenerative pathologies, which develop and persist years after injury…”
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19
The anterior thalamus provides a subcortical circuit supporting memory and spatial navigation
Published in Frontiers in systems neuroscience (30-08-2013)“…The anterior thalamic nuclei (ATN), a central component of Papez' circuit, are generally assumed to be key constituents of the neural circuits responsible for…”
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An Inconvenient Truth: Calcium Sensors Are Calcium Buffers
Published in Trends in neurosciences (Regular ed.) (01-12-2018)“…Recent advances in Ca2+ imaging have given neuroscientists a tool to follow the activity of large numbers of individual neurons simultaneously in vivo in the…”
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