Search Results - "Shan, Zhiying"

Lightweight optimization of passenger car seat frame based on grey relational analysis and optimized coefficient of variation by Shan, Zhiying, Long, Jiangqi, Yu, Ping, Shao, Liang, Liao, Yaoqing

“…At present, the safety performance and lightweight of passenger car seat has become more and more important. The multi-objective lightweight optimization of…”
Get full text

A new fuzzy rule based multi-objective optimization method for cross-scale injection molding of protein electrophoresis microfluidic chips by Shan, Zhiying, Wu, Wangqing, Lei, Yihua, Zhao, Baishun

“…Injection molding is one of the most promising technologies for the large-scale production and application of polymeric microfluidic chips. The multi-objective…”
Get full text

An Effective Shrinkage Control Method for Tooth Profile Accuracy Improvement of Micro-Injection-Molded Small-Module Plastic Gears by Wu, Wangqing, He, Xiansong, Li, Binbin, Shan, Zhiying

“…An effective method to control the non-linear shrinkage of micro-injection molded small-module plastic gears by combining multi-objective optimization with…”
Get full text

Engineering Exosomes to Specifically Target the Mitochondria of Brain Cells by Yan, Xin, Chen, Xinqian, Shan, Zhiying, Bi, Lanrong

“…Mitochondrial dysfunction is associated with various health conditions, including cardiovascular and neurodegenerative diseases. Mitochondrial-targeting…”
Get full text

TNFα Triggers an Augmented Inflammatory Response in Brain Neurons from Dahl Salt-Sensitive Rats Compared with Normal Sprague Dawley Rats by Gao, Huanjia, Bigalke, Jeremy, Jiang, Enshe, Fan, Yuanyuan, Chen, Bojun, Chen, Qing-Hui, Shan, Zhiying

“…Tumor Necrosis Factor (TNF)-α is a proinflammatory cytokine (PIC) and has been implicated in a variety of illness including cardiovascular disease. The current…”
Get full text

A novel class of indole derivatives: enhanced bioavailability, permeability, and antioxidant efficacy for thromboembolic disease therapy by Mandalapu, Srinivas Rao, Hou, Shanshan, Jockusch, Steffen, Shan, Zhiying, Bi, Lanrong

“…Free radicals like reactive oxygen species (ROS) and reactive nitrogen species (RNS) cause cellular damage and contribute to thromboembolic diseases by…”
Get full text

Innovative Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging and Its Utility in Whole-Brain Visualization by Yan, Xin, Chen, Xinqian, Shan, Zhiying, Bi, Lanrong

“…Conducting in vivo brain imaging can be a challenging task due to the complexity of brain tissue and the strict requirements for safe and effective imaging…”
Get full text

Altered Inflammatory Response Is Associated With an Impaired Autonomic Input to the Bone Marrow in the Spontaneously Hypertensive Rat by Zubcevic, Jasenka, Jun, Joo Yun, Kim, Seungbum, Perez, Pablo D., Afzal, Aqeela, Shan, Zhiying, Li, Wencheng, Santisteban, Monica M., Yuan, Wei, Febo, Marcelo, Mocco, Jay, Feng, Yumei, Scott, Edward, Baekey, David M., Raizada, Mohan K.

“…Autonomic nervous system dysfunction, exaggerated inflammation, and impaired vascular repair are all hallmarks of hypertension. Considering that bone marrow…”
Get full text

Conductive 3D nano-biohybrid systems based on densified carbon nanotube forests and living cells by Bagheri, Roya, Ball, Alicia K., Kasraie, Masoud, Chandra, Aparna, Chen, Xinqian, Miskioglu, Ibrahim, Shan, Zhiying, Pour Shahid Saeed Abadi, Parisa

“…Conductive biohybrid cell-material systems have applications in bioelectronics and biorobotics. To date, conductive scaffolds are limited to those with low…”
Get full text

ACE2 and Ang-(1-7) Confer Protection Against Development of Diabetic Retinopathy by Verma, Amrisha, Shan, Zhiying, Lei, Bo, Yuan, Lihui, Liu, Xuan, Nakagawa, Takahiko, Grant, Maria B, Lewin, Alfred S, Hauswirth, William W, Raizada, Mohan K, Li, Qiuhong

“…Despite evidence that hyperactivity of the vasodeleterious axis (ACE/angiotensin II (Ang II)/AT1 receptor) of the renin–angiotensin system (RAS) is associated…”
Get full text

Increased activity of the orexin system in the paraventricular nucleus contributes to salt-sensitive hypertension by Huber, Michael J, Fan, Yuanyuan, Jiang, Enshe, Zhu, Fengli, Larson, Robert A, Yan, Jianqun, Li, Ningjun, Chen, Qing-Hui, Shan, Zhiying

“…The orexin system is involved in arginine vasopressin (AVP) regulation, and its overactivation has been implicated in hypertension. However, its role in…”
Get more information

Direct pro-inflammatory effects of prorenin on microglia by Shi, Peng, Grobe, Justin L, Desland, Fiona A, Zhou, Guannan, Shen, Xiao Z, Shan, Zhiying, Liu, Meng, Raizada, Mohan K, Sumners, Colin

“…Neuroinflammation has been implicated in hypertension, and microglia have been proposed to play an important role in the progression of this disease. Here, we…”
Get full text

Activation of Orexin 1 Receptors in the Paraventricular Nucleus Contributes to the Development of Deoxycorticosterone Acetate-Salt Hypertension Through Regulation of Vasopressin by Bigalke, Jeremy A, Gao, Huanjia, Chen, Qing-Hui, Shan, Zhiying

“…Salt-sensitivity is a major factor in the development of hypertension. The brain orexin system has been observed to play a role in numerous hypertensive animal…”
Get full text

Activation of the (pro)renin receptor in the paraventricular nucleus increases sympathetic outflow in anesthetized rats by Huber, Michael J, Basu, Rupsa, Cecchettini, Cassie, Cuadra, Adolfo E, Chen, Qing-Hui, Shan, Zhiying

“…Previous studies have indicated that hyperactivity of brain prorenin receptors (PRR) is implicated in neurogenic hypertension. However, the role of brain PRR…”
Get more information

Overexpression of corticotropin-releasing factor in the nucleus accumbens enhances the reinforcing effects of nicotine in intact female versus male and ovariectomized female rats by Uribe, Kevin P, Correa, Victor L, Pinales, Briana E, Flores, Rodolfo J, Cruz, Bryan, Shan, Zhiying, Bruijnzeel, Adriaan W, Khan, Arshad M, O'Dell, Laura E

“…This study assessed the role of stress systems in the nucleus accumbens (NAc) in promoting sex differences in the reinforcing effects of nicotine. Intravenous…”
Get full text

Activation of Orexin System Stimulates CaMKII Expression by Fan, Yuanyuan, Jiang, Enshe, Gao, Huanjia, Bigalke, Jeremy, Chen, Bojun, Yu, Chunxiu, Chen, Qinghui, Shan, Zhiying

“…Hyperactivity of the orexin system within the paraventricular nucleus (PVN) has been shown to contribute to increased sympathetic nerve activity (SNA) and…”
Get full text

Aerobic exercise improves depressive symptoms in the unilateral 6-OHDA-lesioned rat model of Parkinson’s disease by Loughlin, Hannah, Jackson, Jacob, Looman, Chloe, Starll, Alayna, Goldman, Jeremy, Shan, Zhiying, Yu, Chunxiu

“…Aerobic exercise has been shown to have established benefits on motor function in Parkinson's disease (PD). However, the impact of exercise on depressive…”
Get full text

Acetic Acid: An Underestimated Metabolite in Ethanol-Induced Changes in Regulating Cardiovascular Function by Chapp, Andrew D, Shan, Zhiying, Chen, Qing-Hui

“…Acetic acid is a bioactive short-chain fatty acid produced in large quantities from ethanol metabolism. In this review, we describe how acetic acid/acetate…”
Get full text

A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link? by Cuadra, Adolfo E, Shan, Zhiying, Sumners, Colin, Raizada, Mohan K

“…The renin-angiotensin system (RAS) plays a central role in the brain to regulate blood pressure (BP). This role includes the modulation of sympathetic nerve…”
Get full text

Induction of Neuroinflammation and Brain Oxidative Stress by Brain-Derived Extracellular Vesicles from Hypertensive Rats by Chen, Xinqian, Yan, Xin, Gingerich, Leah, Chen, Qing-Hui, Bi, Lanrong, Shan, Zhiying

“…Neuroinflammation and brain oxidative stress are recognized as significant contributors to hypertension including salt sensitive hypertension. Extracellular…”
Get full text