Search Results - "Shan, M"
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Optimizing the safety of antibody–drug conjugates for patients with solid tumours
Published in Nature reviews. Clinical oncology (01-08-2023)“…Over the past 5 years, improvements in the design of antibody–drug conjugates (ADCs) have enabled major advances that have reshaped the treatment of several…”
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2
Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages
Published in PloS one (07-12-2015)“…Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic tumor with a dismal prognosis for most patients. Fibrosis and inflammation are hallmarks of…”
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3
Alpha Emitter Radium-223 and Survival in Metastatic Prostate Cancer
Published in The New England journal of medicine (18-07-2013)“…In a study involving men with castration-resistant prostate cancer and bone metastases, the alpha emitter radium-223 significantly prolonged survival, as…”
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4
Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy
Published in Cancer discovery (01-08-2016)“…It remains unclear how obesity worsens treatment outcomes in patients with pancreatic ductal adenocarcinoma (PDAC). In normal pancreas, obesity promotes…”
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5
Patient-reported quality-of-life analysis of radium-223 dichloride from the phase III ALSYMPCA study
Published in Annals of oncology (01-05-2016)“…Radium-223 dichloride (radium-223), a first-in-class α-emitting radiopharmaceutical, is recommended in both pre- and post-docetaxel settings in patients with…”
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6
Assessment of an integrated active solar and air-source heat pump water heating system operated within a passive house in a cold climate zone
Published in Renewable energy (01-03-2016)“…In the pursuit of energy savings and emission reductions, solar energy heating systems have been promoted in China. However, there still exist many barriers to…”
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7
Correcting time‐intensity curves in dynamic contrast‐enhanced breast MRI for inhomogeneous excitation fields at 7T
Published in Magnetic resonance in medicine (01-08-2020)“…Purpose Inhomogeneous excitation at ultrahigh field strengths (7T and above) compromises the reliability of quantified dynamic contrast‐enhanced breast MRI…”
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8
PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity
Published in Clinical cancer research (15-06-2016)“…Obesity promotes pancreatic and breast cancer progression via mechanisms that are poorly understood. Although obesity is associated with increased systemic…”
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9
Origin, types, and contribution of emerging pollutants to environmental degradation and their remediation by physical and chemical techniques
Published in Environmental research (15-09-2024)“…The growing presence of emerging pollutants (EPs) in aquatic environments, as well as their harmful impacts on the biosphere and humans, has become a global…”
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10
An exploratory analysis of alkaline phosphatase, lactate dehydrogenase, and prostate-specific antigen dynamics in the phase 3 ALSYMPCA trial with radium-223
Published in Annals of oncology (01-05-2017)“…Baseline clinical variables are prognostic for overall survival (OS) in patients with castration-resistant prostate cancer (CRPC). Their prognostic and…”
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11
Intrinsic Spin Susceptibility and Pseudogaplike Behavior in Infinite-Layer LaNiO2
Published in Physical review letters (10-05-2021)“…The recent discovery of superconductivity in doped infinite-layer nickelates has stimulated intensive interest, especially for similarities and differences…”
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12
Hydrogen Bonding vs Dihydrogen Bonding in the Air Stable Primary Phosphine ortho‐Phosphinophenol
Published in European journal of inorganic chemistry (02-09-2024)“…ortho‐Phosphinophenol (oPP) is an unusual example of an air‐stable primary phosphine and a valuable precursor to a variety of useful organophosphorus…”
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13
Footwear and Falls in Long-Term Residential Aged Care Facilities: An Analysis of Video Capture Data
Published in Gerontology (Basel) (2024)“…Several footwear characteristics have been shown to affect balance and gait patterns and may therefore influence the risk of falling in older adults. However,…”
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14
Footwear, Orthoses, and Insoles and Their Effects on Balance in Older Adults: A Scoping Review
Published in Gerontology (Basel) (2024)“…Footwear, orthoses, and insoles have been shown to influence balance in older adults; however, it remains unclear which features, singular or in combination,…”
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15
Surfactin inhibits the growth of Propionibacterium acnes by destroying the cell wall and membrane
Published in Letters in applied microbiology (01-12-2021)“…Propionibacterium acnes plays a major role in acne vulgaris. In the pre‐experiment, the growth of P. acnes was inhibited effectively using surfactin; however,…”
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16
Assessment of the effectiveness of the EUROFORGEN NAME and Precision ID Ancestry panel markers for ancestry investigations
Published in Scientific reports (20-09-2021)“…The EUROFORGEN NAME panel is a regional ancestry panel designed to differentiate individuals from the Middle East, North Africa, and Europe. The first version…”
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Adolescent suicide assessment and management in primary care
Published in BMC pediatrics (02-07-2022)“…To understand how suicide management occurs within the primary care setting in terms of follow-up assessments and referral practices. At an initial primary…”
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18
Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease
Published in Journal of proteome research (01-07-2016)“…Alexander disease (AxD) is a neurodegenerative disorder characterized by astrocytic protein aggregates called Rosenthal fibers (RFs). We used mouse models of…”
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Removable isolated singularities for solutions of anisotropic porous medium equation
Published in Annali di matematica pura ed applicata (01-10-2017)“…We study a class of quasilinear parabolic equations with model representative ∂ u ∂ t - ∑ i = 1 n ∂ ∂ x i | u | m i - 1 ∂ u ∂ x i = 0 , m i > 1 , i = 1 , … , s…”
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Factors associated with the development of recurrent and contralateral Charcot neuroarthropathy in individuals with diabetes mellitus: A scoping review
Published in Journal of foot and ankle research (01-12-2024)“…Abstract Introduction Charcot neuroarthropathy (CN) can result in fractures and dislocations of the foot and ankle in individuals with diabetes and neuropathy,…”
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