Search Results - "Shamsutdinova, Diana"

High polygenic predisposition for ADHD and a greater risk of all-cause mortality: a large population-based longitudinal study by Ajnakina, Olesya, Shamsutdinova, Diana, Wimberley, Theresa, Dalsgaard, Søren, Steptoe, Andrew

“…Attention deficit hyperactivity disorder (ADHD) is a highly heritable, neurodevelopmental disorder known to associate with more than double the risk of death…”
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Balancing accuracy and Interpretability: An R package assessing complex relationships beyond the Cox model and applications to clinical prediction by Shamsutdinova, Diana, Stamate, Daniel, Stahl, Daniel

“…Accurate and interpretable models are essential for clinical decision-making, where predictions can directly impact patient care. Machine learning (ML)…”
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Polygenic Propensity for Longevity, APOE-ε4 Status, Dementia Diagnosis, and Risk for Cause-Specific Mortality: A Large Population-Based Longitudinal Study of Older Adults by Ajnakina, Olesya, Shamsutdinova, Diana, Stahl, Daniel, Steptoe, Andrew

“…Abstract To deepen the understanding of genetic mechanisms influencing mortality risk, we investigated the impact of genetic predisposition to longevity and…”
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POLYGENIC PROPENSITY FOR LONGEVITY, APOE-Ε4 STATUS AND GREATER RISK FOR CAUSE-SPECIFIC MORTALITY: A LARGE POPULATION-BASED LONGITUDINAL STUDY by Ajnakina, Olesya, Shamsutdinova, Diana, Stahl, Daniel, Cesarini, David, Steptoe, Andrew

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Schizophrenia polygenic risk score and type 2 diabetes onset in older adults with no schizophrenia diagnosis by Shamsutdinova, Diana, Ajnakina, Olesya, Roberts, Angus, Stahl, Daniel

“…An association between type 2 diabetes (T2DM) and schizophrenia has long been observed, and recent research revealed presence of shared genetic factors…”
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Predicting type 2 diabetes prevalence for people with severe mental illness in a multi-ethnic East London population by Shamsutdinova, Diana, Das-Munshi, Jayati, Ashworth, Mark, Roberts, Angus, Stahl, Daniel

“…•Type 2 diabetes mellitus (T2DM) is common in people with severe mental illness.•Few T2DM prediction models include severe mental illness (SMI); none seem to…”
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A digital imaging analysis (DIA) platform for identifying tertiary lymphoid structures (TLS) in lung adenocarcinoma (LUAD) by Kushnarev, Vladimir, Belozerova, Anna, Dymov, Daniil, Popov, Yuriy, Lukashevich, Nadezhda, Valiev, Ivan, Shamsutdinova, Diana, Akaeva, Aida, Galkin, Ilia, Popyvanov, Lev, Svekolkin, Viktor, Nomie, Krystle, Love, Anna, Bagaev, Alexander, Postovalova, Ekaterina, Fowler, Nathan

“…3142 Background: Previous studies of non-small cell lung cancer (NSCLC) have shown that TLS can be predictive of therapy response and a positive prognostic…”
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Abstract 2742: Integrated multiregional transcriptomic and multi-parameter single-cell imaging analysis of clear cell renal cell carcinoma elucidates diverse cellular communities present within the tumor microenvironment by Miheecheva, Natalia, Ramachandran, Akshaya, Lyu, Yang, Postovalova, Ekaterina, Svekolkin, Viktor, Galkin, Ilia, Ovcharov, Pavel, Shamsutdinova, Diana, Zyrin, Vladimir, Bagaev, Alexander, Nomie, Krystle, Frenkel, Felix, Ataullakhanov, Ravshan, Hsieh, James J.

“…Abstract Although genomic analyses of clear cell renal cell carcinoma (ccRCC) patients have revealed targetable pathways that have led to FDA-approved…”
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Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity by Miheecheva, Natalia, Postovalova, Ekaterina, Lyu, Yang, Ramachandran, Akshaya, Bagaev, Alexander, Svekolkin, Viktor, Galkin, Ilia, Zyrin, Vladimir, Maximov, Vladislav, Lozinsky, Yaroslav, Isaev, Sergey, Ovcharov, Pavel, Shamsutdinova, Diana, Cheng, Emily H., Nomie, Krystle, Brown, Jessica H., Tsiper, Maria, Ataullakhanov, Ravshan, Fowler, Nathan, Hsieh, James J.

“…Intratumor heterogeneity (ITH) represents a major challenge for anticancer therapies. An integrated, multidimensional, multiregional approach dissecting ITH of…”
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Abstract P4-09-02: A molecular classification system for basal-like breast cancer based on the tumor microenvironment is prognostic for survival by Khorkova, Svetlana, Shamsutdinova, Diana, Kushnarev, Vladimir, Popyvanov, Lev, Dymov, Daniil, Zotova, Anastasia, Valiev, Ivan, Antysheva, Zoya, Love, Anna, Brown, Jessica H., Bagaev, Alexander, Kotlov, Nikita, Fowler, Nathan

“…Abstract Recent advancements in molecular profiling have revealed distinct breast cancer subtypes, but many clinical NGS assays rely on gene panels, such as…”
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Abstract P6-04-15: AI-based prediction of tertiary lymphoid structures and lymphocyte immune infiltration in breast carcinomas by Kushnarev, Vladimir, Dymov, Daniil, Lukashevich, Nadezhda, Popyvanov, Lev, Belozerova, Anna, Shamsutdinova, Diana, Akaeva, Aida, Popov, Yury, Khorkova, Svetlana, Valiev, Ivan, Zotova, Anastasia, Brown, Jessica H., Love, Anna, Bagaev, Alexander, Postovalova, Ekaterina, Fowler, Nathan

“…Abstract Introduction Tertiary lymphoid structures (TLSs) and tumor-infiltrating lymphocytes (TILs) in breast carcinomas are prognostic for survival and…”
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Abstract 2143: Cancer of unknown Primary (CUP): Beyond the identification of the site of origin by an integrative genomic approach by Assaad, Majd Al, Sigouros, Michael, Manohar, Jyothi, Guevara, Daniela, Antysheva, Zoia, Kiriy, Daria, Boyko, Alexandra, Samarina, Naira, Shin, Nara, Svekolkin, Viktor, Podsvirova, Svetlana, English, Noel, Villarreal, Alaina, McKenna, Brianna, Tazearslan, Cagdas, Shamsutdinova, Diana, Kushnarev, Vladimir, Kane, Troy, Wilkes, David, Shah, Manish, Ma, Barbara, Tagawa, Scott T., Nanus, David, Nauseef, Jones, Elemento, Olivier, Mosquera, Juan Miguel, Sternberg, Cora N.

“…Abstract CUP is a relatively common diagnosis that accounts for 3-9% of all cancers. The prognosis is poor with median survival of approximately 9 months. The…”
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B cell‐dependent subtypes and treatment‐based immune correlates to survival in stage 3 and 4 lung adenocarcinomas by Raju Paul, Susan, Valiev, Ivan, Korek, Skylar E., Zyrin, Vladimir, Shamsutdinova, Diana, Gancharova, Olga, Zaitsev, Alexander, Nuzhdina, Ekaterina, Davies, Diane L., Dagogo‐Jack, Ibiayi, Frenkel, Felix, Brown, Jessica H., Hess, Joshua M., Viet, Sarah, Petersen, Jason L., Wright, Cameron D., Ott, Harald C., Auchincloss, Hugh G., Muniappan, Ashok, Shioda, Toshihiro, Lanuti, Michael, Davis, Christel M., Ehli, Erik A., Hung, Yin P., Mino‐Kenudson, Mari, Tsiper, Maria, Sluder, Ann E., Reeves, Patrick M., Kotlov, Nikita, Bagaev, Alexander, Ataullakhanov, Ravshan, Poznansky, Mark C.

“…Lung cancer is the leading cause of cancer‐related deaths worldwide. Surgery and chemoradiation are the standard of care in early stages of non‐small cell lung…”
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Sample Size in Natural Language Processing within Healthcare Research by Chaturvedi, Jaya, Shamsutdinova, Diana, Zimmer, Felix, Velupillai, Sumithra, Stahl, Daniel, Stewart, Robert, Roberts, Angus

“…Sample size calculation is an essential step in most data-based disciplines. Large enough samples ensure representativeness of the population and determine the…”
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