Search Results - "Shamsuddin, Abulkalam"
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Protection against cancer by dietary IP6 and inositol
Published in Nutrition and cancer (01-01-2006)“…Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate, abundantly present in many plant sources and in certain high-fiber…”
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Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic
Published in The Journal of nutrition (01-11-2003)“…Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate that is present in substantial amounts in almost all plant and mammalian…”
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Anti-angiogenic activity of inositol hexaphosphate (IP6)
Published in Carcinogenesis (New York) (01-11-2004)“…A significant anticancer activity of the naturally occurring carbohydrate inositol hexaphosphate (IP6) has been reported against numerous cancer models. Since…”
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Anti-cancer function of phytic acid
Published in International journal of food science & technology (01-10-2002)“…Summary Inositol hexaphosphate (InsP6 a.k.a. phytic acid or IP6) is ubiquitous. In the plant kingdom it is particularly abundant in cereals and legumes; in…”
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Inositol hexaphosphate (IP6) inhibits key events of cancer metastasis: I. In vitro studies of adhesion, migration and invasion of MDA-MB 231 human breast cancer cells
Published in Anticancer research (01-09-2003)“…The anti-cancer agent inositol hexaphosphate (IP6) is an abundant intrinsic component of both plant and mammalian cells. In addition to inducing…”
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Inositol hexaphosphate (IP6) inhibits key events of cancer metastasis: II. Effects on integrins and focal adhesions
Published in Anticancer research (01-09-2003)“…We have shown that inositol hexaphosphate (IP6), a natural compound and a potent anti-cancer agent, inhibited cancer cell adhesion to the extracellular matrix…”
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Inositol hexaphosphate (IP6) enhances the anti-proliferative effects of adriamycin and tamoxifen in breast cancer
Published in Breast cancer research and treatment (01-06-2003)“…The current treatment of breast carcinomas recognizes the importance of combination therapy in order to increase efficacy and decrease side effects of…”
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Inositol phosphates have novel anticancer function
Published in The Journal of nutrition (01-03-1995)“…Inositol hexaphosphate (InsP6, phytic acid) is ubiquitous in the plant kingdom and is abundant in cereals and legumes. In much smaller amounts InsP6 and its…”
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Two new actions of sea nettle ( Chrysaora quinquecirrha) nematocyst venom: studies on the mechanism of actions on complement activation and on the central nervous system
Published in Toxicon (Oxford) (15-12-2004)“…Chrysaora quinquecirrha (sea nettle) nematocyst venom is lethal to rainbow killifish ( Adina xenica) when injected intraperitoneally or topically applied to…”
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Absorption and excretion of orally administered inositol hexaphosphate (IP6 or phytate) in humans
Published in BioFactors (Oxford) (2001)“…A study of the pharmacokinetic profile (oral absorption and renal excretion) of inositol hexaphosphate or phytate (IP6) is presented. Seven healthy volunteers…”
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Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells
Published in Carcinogenesis (New York) (01-08-1995)“…We investigated the effects of inositol hexaphosphate (InsP6) on growth inhibition and differentiation of human prostate cancer cells PC-3 in vitro. A…”
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Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer
Published in Carcinogenesis (New York) (01-05-1995)“…Because inositol hexaphosphate (InsP6) and inositol (Ins), contained in plants and most mammalian cells, have been demonstrated to have anti-cancer and…”
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[3H]phytic acid (inositol hexaphosphate) is absorbed and distributed to various tissues in rats
Published in The Journal of nutrition (01-04-1993)“…To understand the mechanism of antineoplastic action of phytic acid, we investigated the absorption and distribution of myo-[inositol-2-3H(N)] hexakisphosphate…”
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Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid)
Published in Carcinogenesis (New York) (01-09-1993)“…Inositol hexaphosphate (InsP6 or phytic acid) has been shown to have antineoplastic action in in vivo models of colon carcinogenesis. We therefore investigated…”
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Detection of Benzo[a]pyrene Diol Epoxide--DNA Adducts in Peripheral Blood Lymphocytes and Antibodies to the Adducts in Serum from Coke Oven Workers
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1985)“…Coke oven workers are exposed to high levels of carcinogenic polycyclic aromatic hydrocarbons, including benzo[a]pyrene (B[a]P), and are at increased risk of…”
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Transformation of Human Bronchial Epithelial Cells Transfected by Harvey ras Oncogene
Published in Science (American Association for the Advancement of Science) (08-03-1985)“…Transfection of normal human bronchial epithelial (NHBE) cells with a plasmid carrying the ras oncogene of Harvey murine sarcoma virus (v-Ha ras) changed the…”
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Effects of inositol hexaphosphate on growth and differentiation in K-562 erythroleukemia cell line
Published in Cancer letters (10-07-1992)“…Inositol hexaphosphate (InsP6) has recently been shown to inhibit experimental cancers in vivo. Since the lower phosphorylated forms of InsP6 are important in…”
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Inositol and inositol hexaphosphate suppress cell proliferation and tumor formation in CD-1 mice
Published in Carcinogenesis (New York) (01-08-1989)“…In previous studies, we have shown that inositol hexaphosphate (InsP6), a constituent of cereal diet, inhibited azoxymethane-induced experimental large…”
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Inositol hexaphosphate inhibits large intestinal cancer in F344 rats 5 months after induction by azoxymethane
Published in Carcinogenesis (New York) (01-03-1989)“…A treatment regimen of 2% Na-InsP6 in drinking water was effective in significantly reducing large intestinal cancer in F344 rats even when the treatment was…”
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