Search Results - "Shams, Mahmood"
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Synthesis, biological assay in vitro and molecular docking studies of new Schiff base derivatives as potential urease inhibitors
Published in European journal of medicinal chemistry (01-11-2011)“…A series of new and novel Schiff base derivatives were synthesized and investigated as potential new inhibitors of Jack bean urease. The most potent compounds…”
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Iminothiazoline-Sulfonamide Hybrids as Jack Bean Urease Inhibitors; Synthesis, Kinetic Mechanism and Computational Molecular Modeling
Published in Chemical biology & drug design (01-03-2016)“…The present work reports the synthesis of several 2‐iminothiazoline derivatives of sulfanilamide (3a–j) as inhibitors of jack bean ureases. The title compounds…”
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Selective Removal of Lead (II) Ions from Wastewater with Fabricated ZnO-PVA Membrane
Published in JOM (1989) (01-12-2023)“…Water contamination is a serious threat to living organisms and the contamination is increasing day by day due to versatile applications of heavy metal ions…”
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Synthesis, biological evaluation and computational studies of novel iminothiazolidinone benzenesulfonamides as potent carbonic anhydrase II and IX inhibitors
Published in Bioorganic chemistry (01-04-2018)“…[Display omitted] •The synthesis of a series of iminothiazolidinone benzenesulfonamides was reported.•The iminothiazolidinones were investigated as hCA I, II,…”
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Molecular and clinical profile of type 2 von Willebrand disease in Iran: a thirteen-year experience
Published in International journal of hematology (01-04-2020)“…Type 2 von Willebrand disease (VWD) is the most common congenital bleeding disorder, with variable bleeding tendency and a complex laboratory phenotype. In the…”
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Synthesis, Biological Evaluation and Molecular Docking Studies of Novel Coumarinylthiazolyl Iminothiazolidinone Hybrids as Potent Urease Inhibitors
Published in ChemistrySelect (Weinheim) (14-05-2020)“…The present paper is designed to explore the potential of an important class of heterocycles coumarinylthiazolyl iminothiazolidinone to inhibit jack bean…”
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Discovery of isoxazolyl-based inhibitors of Plasmodium falciparum cGMP-dependent protein kinase
Published in RSC medicinal chemistry (01-01-2020)“…The cGMP-dependent protein kinase in (PfPKG) plays multiple roles in the life cycle of the parasite. As a result, this enzyme is a potential target for new…”
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Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase
Published in ACS medicinal chemistry letters (09-12-2021)“…The discovery of new targets for the treatment of malaria, in particular those aimed at the pre-erythrocytic stage in the life cycle, advanced with the…”
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Biological Evaluation of Azomethine-dihydroquinazolinone Conjugates as Cancer and Cholinesterase Inhibitors
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-01-2016)“…In an attempt to discover novel anti-cancer agents and potent cholinesterase inhibitors, 11 azomethine-dihydroquinazolinone conjugates were evaluated against…”
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Laboratory Diagnosis of Factor XIII Deficiency in Developing Countries: An Iranian Experience
Published in Laboratory medicine (01-08-2016)“…Factor XIII (FXIII) deficiency is an extremely rare bleeding disorder with an approximately 12-times higher than the rest of the world. The International…”
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Synthesis and Crystal Structure of 3-(4-Methoxyphenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
Published in Crystals (Basel) (29-08-2011)“…Synthesis of the title compound from 4-methoxyaniline was accomplished in three steps. The structure was supported by spectroscopic data and unambiguously…”
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Status of major hemostatic components in the setting of COVID-19: the effect on endothelium, platelets, coagulation factors, fibrinolytic system, and complement
Published in Annals of hematology (01-06-2023)“…The coagulation, fibrinolytic, anticoagulation, and complement systems are in delicate balance with the vessel wall endothelium ensuring appropriate…”
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Cancer-associated thrombosis: the role of inherited thrombophilia
Published in Blood coagulation & fibrinolysis (01-09-2024)“…Cancer-associated thrombosis (CAT) is a common complication and a major cause of morbidity and mortality in patients with active cancers. CAT is common in…”
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Factor VII Padua in Iran: clinical and laboratory findings of three unrelated patients
Published in Blood coagulation & fibrinolysis (01-04-2023)“…The congenital factor VII (FVII) deficiency with an estimated incidence of one per 300 000 is the most common rare congenital bleeding disorder. The…”
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Factor VII Padua in Iran: clinical and laboratory findings of three unrelated patients
Published in Blood coagulation & fibrinolysis (30-01-2023)“…The congenital factor VII (FVII) deficiency with an estimated incidence of one per 300 000 is the most common rare congenital bleeding disorder. The…”
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Congenital Bleeding Disorders and COVID-19-A Systematic Literature Review
Published in Seminars in thrombosis and hemostasis (01-06-2024)“…Hypercoagulability is a prominent feature of coronavirus disease 2019 (COVID-19) and can lead to fatal consequences. Although the impact of COVID-19 on several…”
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A Comprehensive Overview of Coagulation Factor V and Congenital Factor V Deficiency
Published in Seminars in thrombosis and hemostasis (01-07-2019)“…Coagulation factor (F) V is a glycoprotein that plays an essential role in the formation of the prothrombinase complex, which is critical for progressing clot…”
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Falsely prolonged prothrombin time test in a patient with erythrocytosis: a case report
Published in Blood coagulation & fibrinolysis (01-04-2024)“…The prothrombin time (PT) test is commonly used to monitor deficiencies in coagulation factors. A prolonged PT may indicate a deficiency of factors II, V, VII,…”
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