Search Results - "Shammas, Hadeel"

Different Niemann-Pick C1 Genotypes Generate Protein Phenotypes that Vary in their Intracellular Processing, Trafficking and Localization by Shammas, Hadeel, Kuech, Eva-Maria, Rizk, Sandra, Das, Anibh M., Naim, Hassan Y.

“…Niemann-Pick Type C (NP-C) is an inherited neurovisceral lysosomal storage disease characterized by a defect in the trafficking of endocytosed cholesterol. In…”
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Different Trafficking Phenotypes of Niemann-Pick C1 Gene Mutations Correlate with Various Alterations in Lipid Storage, Membrane Composition and Miglustat Amenability by Brogden, Graham, Shammas, Hadeel, Walters, Friederike, Maalouf, Katia, Das, Anibh M, Naim, Hassan Y, Rizk, Sandra

“…Niemann-Pick Type C (NPC) is an autosomal recessive lysosomal storage disease leading to progressive neurodegeneration. Mutations in the gene, which accounts…”
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Impact of Dietary Modifications on Plasma Sirtuins 1, 3 and 5 in Older Overweight Individuals Undergoing 12-Weeks of Circuit Training by Wasserfurth, Paulina, Nebl, Josefine, Rühling, Miriam Rebekka, Shammas, Hadeel, Bednarczyk, Jolanthe, Koehler, Karsten, Boßlau, Tim Konstantin, Krüger, Karsten, Hahn, Andreas, Das, Anibh Martin

“…Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases that regulate numerous pathways such as mitochondrial energy metabolism in the…”
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Analysis of Sirtuin 1 and Sirtuin 3 at Enzyme and Protein Levels in Human Breast Milk during the Neonatal Period by Hase, Kristina, Stahmer, Laura, Shammas, Hadeel, Peter, Corinna, Bohnhorst, Bettina, Das, Anibh Martin

“…Breast feeding is regarded as the preferred nutrition modality for children during the first few months of life. It not only furthers growth and development…”
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Effect of Rosa canina Methanol Extract on Membrane Trafficking in Different Niemann‐Pick C1 Phenotypes by Wanes, Dalanda, Al Aoua, Sherin, Walters, Friederike, Shammas, Hadeel, Y. Naim, Hassan

“…Niemann Pick type C (NPC) disease is an autosomal recessive lysosomal storage disorder that is caused by mutations in Niemann‐Pick C1 (NPC1) or Niemann‐Pick C2…”
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Niemann‐Pick C1 Pathophysiology Associates with Different Classes of Protein Trafficking Phenotypes Elicited by NPC‐1 Mutations by Shammas, Hadeel, Rizk, Sandra, Das, Anibh, Naim, Hassan Y.

“…Niemann‐Pick Type C disease (NP‐C) is caused by a defect in the trafficking of endocytosed cholesterol with sequestration of cholesterol in lysosomes and late…”
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Rosa canina L. Methanol Extract and Its Component Rutin Reduce Cholesterol More Efficiently than Miglustat in Niemann–Pick C Fibroblasts by Wanes, Dalanda, Al Aoua, Sherin, Shammas, Hadeel, Walters, Friederike, Das, Anibh M, Rizk, Sandra, Naim, Hassan Y

“…Niemann–Pick type C (NPC) disease is an autosomal recessive lysosomal storage disorder where 95% of the cases are caused by mutations in the Niemann–Pick C1…”
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Case study on the pathophysiology of Fabry disease: abnormalities of cellular membranes can be reversed by substrate reduction in vitro by Brogden, Graham, Shammas, Hadeel, Maalouf, Katia, Naim, Samara L, Wetzel, Gabi, Amiri, Mahdi, von Köckritz-Blickwede, Maren, Das, Anibh M, Naim, Hassan Y

“…It is still not entirely clear how α-galactosidase A (GAA) deficiency translates into clinical symptoms of Fabry disease (FD). The present communication…”
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Lipid raft abnormalities and subsequent protein trafficking effects in Niemann‐Pick type C1 (LB158) by Kuech, Eva‐Maria, Shammas, Hadeel, Maalouf, Katia E., Koeckritz‐Blickwede, Maren, Das, Anibh M., Naim, Hassan Y.

“…Many proteins and lipid components are organized within membrane microdomains, known as lipid rafts (LR). LR are cholesterol‐ and sphingolipid‐rich membranes…”
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The Pathobiochemistry of Gastrointestinal Symptoms in a Patient with Niemann-Pick Type C Disease by Amiri, Mahdi, Kuech, Eva-Maria, Shammas, Hadeel, Wetzel, Gabi, Naim, Hassan Y.

“…The molecular basis of gastrointestinal intolerances in a severe case of Niemann-Pick type C disease was analyzed in an intestinal biopsy specimen. The enzyme…”
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