Search Results - "Shamji, Betty"
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Barrier disrupting effects of alternaria alternata extract on bronchial epithelium from asthmatic donors
Published in PloS one (23-08-2013)“…Sensitization and exposure to the allergenic fungus Alternaria alternata has been associated with increased risk of asthma and asthma exacerbations. The first…”
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2
IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo
Published in American journal of respiratory and critical care medicine (15-12-2014)“…Rhinoviruses are the major cause of asthma exacerbations; however, its underlying mechanisms are poorly understood. We hypothesized that the epithelial…”
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3
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation
Published in Science translational medicine (01-10-2014)“…Rhinoviruses (RVs), which are the most common cause of virally induced asthma exacerbations, account for much of the burden of asthma in terms of morbidity,…”
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4
Interleukin-18 Is Associated With Protection Against Rhinovirus-Induced Colds and Asthma Exacerbations
Published in Clinical infectious diseases (15-05-2015)“…Rhinoviruses cause the common cold and exacerbations of asthma. Animal models of infection have identified a protective role for interleukin-18 (IL-18)…”
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A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)
Published in EBioMedicine (01-05-2017)“…Rhinovirus infection is a major cause of asthma exacerbations. We studied nasal and bronchial mucosal inflammatory responses during experimental…”
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A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid
Published in Journal of allergy and clinical immunology (01-06-2010)“…Assay specificity was suggested from the association between levels of IL-5 and IL-13 (β-coefficient, 1.11; 95% CI, 0.7-1.6; P < .0001; r2 = 0.52). [...]we…”
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7
IL-33–Dependent Type 2 Inflammation during Rhinovirus-induced Asthma Exacerbations In Vivo
Published in American journal of respiratory and critical care medicine (15-12-2014)Get full text
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8
Expression and Cellular Provenance of Thymic Stromal Lymphopoietin and Chemokines in Patients with Severe Asthma and Chronic Obstructive Pulmonary Disease
Published in The Journal of immunology (1950) (15-08-2008)“…Asthma and chronic obstructive pulmonary disease (COPD) are associated with Th2 and Th1 differentiated T cells. The cytokine thymic stromal lymphopoietin…”
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Oxidative Stress-induced Antibodies to Carbonyl-modified Protein Correlate with Severity of Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-10-2011)“…There is increasing evidence for the presence of autoantibodies in chronic obstructive pulmonary disease (COPD). Chronic oxidative stress is an essential…”
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The Th2 Cell-Promoting Cytokines IL-33 and TSLP, but Not IL-25, Are Potential Biomarkers for Endotypes of Asthma
Published in Chest (01-04-2016)Get full text
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11
IL-15 complexes induce NK cell and T cell responses independent of type I IFN signalling during rhinovirus infection
Published in Mucosal immunology (29-01-2014)“…Rhinoviruses are the most common virus to infect man causing a range of serious respiratory diseases including exacerbations of asthma and COPD. Type I IFN and…”
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Barrier Disrupting Effects of Alternaria Alternata Extract on Bronchial Epithelium from Asthmatic Donors: e71278
Published in PloS one (01-08-2013)“…Sensitization and exposure to the allergenic fungus Alternaria alternata has been associated with increased risk of asthma and asthma exacerbations. The first…”
Get full text
Journal Article