Search Results - "Shamblott, Michael"

Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate by Gomez, Danielle L, O'Driscoll, Marci, Sheets, Timothy P, Hruban, Ralph H, Oberholzer, Jose, McGarrigle, James J, Shamblott, Michael J

“…Neurogenin 3 (NGN3) is necessary and sufficient for endocrine differentiation during pancreatic development and is expressed by a population of progenitor…”
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Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ by Pendleton, James C., Shamblott, Michael J., Gary, Devin S., Belegu, Visar, Hurtado, Andres, Malone, Misti L., McDonald, John W.

“…CNS damage often results in demyelination of spared axons due to oligodendroglial cell death and dysfunction near the injury site. Although new oligodendroglia…”
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Derivation of Pluripotent Stem Cells from Cultured Human Primordial Germ Cells by Shamblott, Michael J., Axelman, Joyce, Wang, Shunping, Bugg, Elizabeth M., Littlefield, John W., Donovan, Peter J., Blumenthal, Paul D., Huggins, George R., Gearhart, John D.

“…Human pluripotent stem cells would be invaluable for in vitro studies of aspects of human embryogenesis. With the goal of establishing pluripotent stem cell…”
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Physical transfer of membrane and cytoplasmic components as a general mechanism of cell-cell communication by Niu, Xinle, Gupta, Kshitiz, Yang, Joy T, Shamblott, Michael J, Levchenko, Andre

“…Recent evidence from different research areas has revealed a novel mechanism of cell-cell communication by spontaneous intercellular transfer of cellular…”
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Use of perfluorocarbon nanoparticles for non-invasive multimodal cell tracking of human pancreatic islets by Barnett, Brad P, Ruiz-Cabello, Jesus, Hota, Partha, Ouwerkerk, Ronald, Shamblott, Michael J, Lauzon, Cal, Walczak, Piotr, Gilson, Wesley D, Chacko, Vadappuram P, Kraitchman, Dara L, Arepally, Aravind, Bulte, Jeff W M

“…In vivo imaging of engraftment and immunorejection of transplanted islets is critical for further clinical development, with (1)H MR imaging of…”
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Human Embryonic Germ Cell Derivatives Facilitate Motor Recovery of Rats with Diffuse Motor Neuron Injury by Kerr, Douglas A, Llado, Jeronia, Shamblott, Michael J, Maragakis, Nicholas J, Irani, David N, Crawford, Thomas O, Krishnan, Chitra, Dike, Sonny, Gearhart, John D, Rothstein, Jeffrey D

“…We have investigated the potential of human pluripotent cells to restore function in rats paralyzed with a virus-induced motor neuronopathy. Cells derived from…”
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625 Immune priming IFx-Hu2.0 promotes antibody responses necessary for anti-PD1 responses in PD-1 refractory melanoma patients by Markowitz, Joseph, Shamblott, Michael, Brohl, Andrew S, Sarnaik, Amod A, Eroglu, Zeynep, Khushalani, Nikhil I, Dukes, Christopher W, Chamizo, Alejandra, Bastawrous, Marina, Garcia, Edward, Delhawi, Ashraf, Chen, Pei-Ling, Aquino, Deanryan BDe, Sondak, Vernon K, Tarhini, Ahmad A, Kim, Youngchul, Lawman, Patricia, Pilon-Thomas, Shari

“…BackgroundIFx-Hu2.0 is a plasmid encoding the streptococcal Emm55 protein formulated for transfection into mammalian cells. Previous work demonstrated that…”
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Human Embryonic Germ Cell Derivatives Express a Broad Range of Developmentally Distinct Markers and Proliferate Extensively in vitro by Shamblott, Michael J., Axelman, Joyce, Littlefield, John W., Blumenthal, Paul D., Huggins, George R., Cui, Yan, Cheng, Linzhao, Gearhart, John D.

“…Human pluripotent stem cells (hPSCs) have been derived from the inner cell mass cells of blastocysts (embryonic stem cells) and primordial germ cells of the…”
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Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas by Shamblott, Michael J, O'Driscoll, Marci L, Gomez, Danielle L, McGuire, Dustin L

“…Reports of exocrine-to-endocrine reprogramming through expression or stabilization of the transcription factor neurogenin 3 (NGN3) have generated renewed…”
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Hypomorphic interleukin-7 receptor α-chain mutations and T-cell deficiency: a delay in diagnosis by Leiding, Jennifer W., MD, Sriaroon, Panida, MD, Ly, Jean M.B., MD, Petrovic, Aleksandra, MD, Howard, Deborah L., MS, Shamblott, Michael, PhD, Kuehn, Hye-Sun, PhD, Fleisher, Thomas A., MD

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Proliferation and pluripotency of human embryonic stem cells maintained on type I collagen by Jones, Meredith B, Chu, Chia H, Pendleton, James C, Betenbaugh, Michael J, Shiloach, Joseph, Baljinnyam, Bolormaa, Rubin, Jeffrey S, Shamblott, Michael J

“…Human embryonic stem cells (hESC) require a balance of growth factors and signaling molecules to proliferate and retain pluripotency. Conditioned medium (CM)…”
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OCT3/4 regulates transcription of histone deacetylase 4 (Hdac4) in mouse embryonic stem cells by Addis, Russell C., Prasad, Megana K., Yochem, Robert L., Zhan, Xiangcan, Sheets, Timothy P., Axelman, Joyce, Patterson, Ethan S., Shamblott, Michael J.

“…OCT3/4 is a POU domain transcription factor that is critical for maintenance of pluripotency and self‐renewal by embryonic stem (ES) cells and cells of the…”
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Transplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damage by Mueller, Dawn, Shamblott, Michael J., Fox, Harold E., Gearhart, John D., Martin, Lee J.

“…Stem cell therapy is a hope for the treatment of some childhood neurological disorders. We examined whether human neural stem cells (hNSCs) replace lost cells…”
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Musculoskeletal Differentiation of Cells Derived from Human Embryonic Germ Cells by Kim, Myoung Sook, Hwang, Nathaniel S., Lee, Janice, Kim, Tae‐Kyun, Leong, Kam, Shamblott, Michael J., Gearhart, John, Elisseeff, Jennifer

“…Stem cells have the potential to significantly improve cell and tissue regeneration therapies, but little is understood about how to control their behavior. We…”
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Stem cell profiling by nuclear magnetic resonance spectroscopy by Jansen, Jacobus F.A., Shamblott, Michael J., van Zijl, Peter C.M., Lehtimäki, Kimmo K., Bulte, Jeff W.M., Gearhart, John D., Hakumäki, Juhana M.

“…The classification of embryonic and adult stem cells, including their derivatives, is still limited, and often these cells are best defined by their functional…”
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Generation of humanized animal livers using embryoid body-derived stem cell transplant by Locke, Jayme E, Sun, Zhaoli, Warren, Daniel S, Sheets, Timothy P, Holzer, Horatio, Shamblott, Michael J, Montgomery, Robert A, Cameron, Andrew M

“…Animal organs engineered to be chimeric for human cells could contribute significantly to the field of transplantation, including studies of human-specific…”
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Pluripotent stem cells from germ cells by Kerr, Candace L, Shamblott, Michael J, Gearhart, John D

“…To date, stem cells have been derived from three sources of germ cells. These include embryonic germ cells (EGCs), embryonal carcinoma cells (ECCs), and…”
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Monoallelic Expression and Methylation of Imprinted Genes in Human and Mouse Embryonic Germ Cell Lineages by Onyango, Patrick, Jiang, Shan, Uejima, Hiroshi, Shamblott, Michael J., Gearhart, John D., Cui, Hengmi, Feinberg, Andrew P.

“…Imprinting is an epigenetic modification leading to monoallelic expression of some genes, and disrupted imprinting is believed to be a barrier to human stem…”
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Embryonic germ cells are capable of adipogenic differentiation in vitro and in vivo by Hillel, Alexander T, Varghese, Shyni, Petsche, Jennifer, Shamblott, Michael J, Elisseeff, Jennifer H

“…There is an extensive clinical need for soft tissue filler materials, such as adipose tissue, for plastic and reconstructive surgery. Due to limitations with…”
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SOX17 directly activates Zfp202 transcription during in vitro endoderm differentiation by Patterson, Ethan S, Addis, Russell C, Shamblott, Michael J, Gearhart, John D

“…1 Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 2 McKusick-Nathans Institute of Genetic Medicine, Johns…”
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