Search Results - "Shama, Noura M Abo"
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Naturally Available Flavonoid Aglycones as Potential Antiviral Drug Candidates against SARS-CoV-2
Published in Molecules (Basel, Switzerland) (29-10-2021)“…Flavonoids are important secondary plant metabolites that have been studied for a long time for their therapeutic potential in inflammatory diseases because of…”
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Iterated Virtual Screening-Assisted Antiviral and Enzyme Inhibition Assays Reveal the Discovery of Novel Promising Anti-SARS-CoV-2 with Dual Activity
Published in International journal of molecular sciences (22-08-2021)“…Unfortunately, COVID-19 is still a threat to humankind and has a dramatic impact on human health, social life, the world economy, and food security. With the…”
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3
Common childhood vaccines do not elicit a cross-reactive antibody response against SARS-CoV-2
Published in PloS one (28-10-2020)“…Anecdotal evidence showed a negative correlation between Bacille Calmette-Guérin (BCG) vaccination and incidence of COVID-19. Incidence of the disease in…”
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4
Synthesis of Potential Antiviral Agents for SARS-CoV-2 Using Molecular Hybridization Approach
Published in Molecules (Basel, Switzerland) (01-09-2022)“…We synthesized a set of small molecules using a molecular hybridization approach with good yields. The antiviral properties of the synthesized conjugates…”
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Incidence and Seroprevalence of Avian Influenza in a Cohort of Backyard Poultry Growers, Egypt, August 2015-March 2019
Published in Emerging infectious diseases (01-09-2020)“…Currently enzootic avian influenza H5N1, H9N2, and H5N8 viruses were introduced into poultry in Egypt in 2006, 2011, and 2016, respectively. Infections with…”
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Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibodies in Egyptian Convalescent Plasma Donors
Published in Frontiers in microbiology (24-11-2020)“…Using convalescent plasma as immunotherapy is an old method for treatment of infectious diseases. Several countries have recently allowed the use of such…”
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Assaying for antiviral activity of the folkloric medicinal desert plant Rhazya stricta on coronavirus SARS-CoV-2
Published in Biotechnology, biotechnological equipment (31-12-2022)“…The emergence of superbugs and resistant pathogens poses a challenge in scientific and medical research as they threaten public health worldwide. Many herbal…”
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Anti-rheumatic colchicine phytochemical exhibits potent antiviral activities against avian and seasonal Influenza A viruses (IAVs) via targeting different stages of IAV replication cycle
Published in BMC complementary and alternative medicine (22-01-2024)“…The continuous evolution of drug-resistant influenza viruses highlights the necessity for repurposing naturally-derived and safe phytochemicals with…”
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Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection
Published in Journal of Genetic Engineering and Biotechnology (01-12-2023)“…Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein…”
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Comparative evaluation of flavonoids reveals the superiority and promising inhibition activity of silibinin against SARS‐CoV‐2
Published in Phytotherapy research (01-07-2022)“…Flavonoids are phenolic compounds naturally found in plants and commonly consumed in diets. Herein, flavonoids were sequentially evaluated by a comparative in…”
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β-Blockers bearing hydroxyethylamine and hydroxyethylene as potential SARS-CoV-2 Mpro inhibitors: rational based design, in silico , in vitro , and SAR studies for lead optimization
Published in RSC advances (28-10-2021)“…The global COVID-19 pandemic became more threatening especially after the introduction of the second and third waves with the current large expectations for a…”
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Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies
Published in Scientific reports (28-07-2022)“…During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic…”
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EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2
Published in PloS one (18-11-2020)“…Due to the challenges for developing vaccines in devastating pandemic situations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing…”
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Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2022)“…The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt development of new effective therapeutic interventions for the battle against…”
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Prevalence of viral pathogens in a sample of hospitalized Egyptian children with acute lower respiratory tract infections: a two-year prospective study
Published in Bulletin of the National Research Centre (01-01-2022)“…Background Viral pneumonias are a major cause of childhood mortality. Proper management needs early and accurate diagnosis. This study objective is to…”
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Antiviral activities of plant-derived indole and β-carboline alkaloids against human and avian influenza viruses
Published in Scientific reports (28-01-2023)“…The persistent evolution of drug-resistant influenza strains represents a global concern. The innovation of new treatment approaches through drug screening…”
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Incidence, household transmission, and neutralizing antibody seroprevalence of Coronavirus Disease 2019 in Egypt: Results of a community-based cohort
Published in PLoS pathogens (01-03-2021)“…SARS-CoV-2 virus is transmitted in closed settings to people in contact with COVID-19 patients such as healthcare workers and household contacts. However,…”
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Incidence and neutralizing antibody seroprevalence of influenza B virus in Egypt: Results of a community-based cohort study
Published in PloS one (29-06-2022)“…Since 2000, two lineages of influenza B viruses, Victoria and Yamagata, have been circulating at similar frequencies worldwide. Little is known about the…”
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Identification of potential antiviral compounds from Egyptian Red Sea soft corals against Middle East respiratory syndrome coronavirus
Published in Natural product research (01-10-2024)“…The ongoing threat of Middle East respiratory syndrome coronavirus (MERS-CoV) underscores the importance of developing effective antiviral treatments. Current…”
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Incidence and seroprevalence of seasonal influenza a viruses in Egypt: Results of a community‐based cohort study
Published in Influenza and other respiratory viruses (01-07-2022)“…Background H1N1 and H3N2 influenza A viruses circulate in people as seasonal influenza viruses. Data on influenza infection rates and circulation in…”
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