Search Results - "Shalhoub, Ruba N"

Granulocyte transfusions in severe aplastic anemia by Rajput, Roma V, Shah, Vaani, Shalhoub, Ruba N, West-Mitchell, Kamille, Cha, Nu Ri, Conry-Cantilena, Cathy, Leitman, Susan F, Young, David J, Wells, Brian, Aue, Georg, Dunbar, Cynthia E, Patel, Bhavisha A, Childs, Richard W, Young, Neal S, Wu, Colin O, Groarke, Emma M, Kalsi, Shelley S

“…Patients with severe aplastic anemia (SAA) are at high risk of morbidity and mortality due to severe infections. We aimed to characterize the role of…”
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Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag by Winkler, Thomas, Fan, Xing, Cooper, James, Desmond, Ronan, Young, David J., Townsley, Danielle M., Scheinberg, Phillip, Grasmeder, Sophia, Larochelle, Andre, Desierto, Marie, Valdez, Janet, Lotter, Jennifer, Wu, Colin, Shalhoub, Ruba N., Calvo, Katherine R., Young, Neal S., Dunbar, Cynthia E.

“…Eltrombopag (EPAG) received approval from the US Food and Drug Administration for the treatment of refractory severe aplastic anemia (rSAA) based on treatment…”
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Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias by Fan, Xing, Desmond, Ronan, Winkler, Thomas, Young, David J., Dumitriu, Bogdan, Townsley, Danielle M., Gutierrez-Rodrigues, Fernanda, Lotter, Jennifer, Valdez, Janet, Sellers, Stephanie E., Barranta, Ma Evette, Shalhoub, Ruba N., Wu, Colin O., Albitar, Maher, Calvo, Katherine R., Young, Neal S., Dunbar, Cynthia E.

“…There is no standard or widely effective treatment of patients with moderate aplastic anemia (MAA) or hypo-productive uni-lineage cytopenias (UC). Eltrombopag…”
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Spectrum of clonal hematopoiesis in VEXAS syndrome by Gutierrez-Rodrigues, Fernanda, Kusne, Yael, Fernandez, Jenna, Lasho, Terra, Shalhoub, Ruba, Ma, Xiaoyang, Alessi, Hugh, Finke, Christy, Koster, Matthew J., Mangaonkar, Abhishek, Warrington, Kenneth J., Begna, Kebede, Xie, Zhuoer, Ombrello, Amanda K., Viswanatha, David, Ferrada, Marcela, Wilson, Lorena, Go, Ronald, Kourelis, Taxiarchis, Reichard, Kaaren, Olteanu, Horatiu, Darden, Ivana, Hironaka, Dalton, Alemu, Lemlem, Kajigaya, Sachiko, Rosenzweig, Sofia, Calado, Rodrigo T., Groarke, Emma M., Kastner, Daniel L., Calvo, Katherine R., Wu, Colin O., Grayson, Peter C., Young, Neal S., Beck, David B., Patel, Bhavisha A., Patnaik, Mrinal M.

“…•UBA1 mutations are primarily responsible for myeloid clonal expansion and both the inflammatory and hematologic phenotype in VEXAS.•Patients with VEXAS have…”
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Differential diagnosis of bone marrow failure syndromes guided by machine learning by Gutierrez-Rodrigues, Fernanda, Munger, Eric, Ma, Xiaoyang, Groarke, Emma M., Tang, Youbao, Patel, Bhavisha A., Catto, Luiz Fernando B., Clé, Diego V., Niewisch, Marena R., Alves-Paiva, Raquel M., Donaires, Flávia S., Pinto, André Luiz, Borges, Gustavo, Santana, Barbara A., McReynolds, Lisa J., Giri, Neelam, Altintas, Burak, Fan, Xing, Shalhoub, Ruba, Siwy, Christopher M., Diamond, Carrie, Raffo, Diego Quinones, Craft, Kathleen, Kajigaya, Sachiko, Summers, Ronald M., Liu, Paul, Cunningham, Lea, Hickstein, Dennis D., Dunbar, Cynthia E., Pasquini, Ricardo, De Oliveira, Michel Michels, Velloso, Elvira D. R. P., Alter, Blanche P., Savage, Sharon A., Bonfim, Carmem, Wu, Colin O., Calado, Rodrigo T., Young, Neal S.

“…•We developed a machine-learning algorithm to guide differential diagnosis of BMF.•Acquired vs inherited prediction relied on 25 variables recorded through a…”
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Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescuing and cancer mutations by Gutierrez-Rodrigues, Fernanda, Groarke, Emma M, Thongon, Natthakan, Rodriguez-Sevilla, Juan Jose, Bazzo Catto, Luiz Fernando, Niewisch, Marena Rebekka, Shalhoub, Ruba N, McReynolds, Lisa J, Clé, Diego V, Patel, Bhavisha A, Ma, Xiaoyang, Hironaka, Dalton, Donaires, Flavia S, Spitofsky, Nina R, Santana, Barbara A, Lai, Tsung-Po, Alemu, Lemlem, Kajigaya, Sachiko, Darden, Ivana, Zhou, Weiyin, Browne, Paul V, Paul, Subrata, Lack, Justin, Young, David J, DiNardo, Courtney D, Aviv, Abraham, Ma, Feiyang, Michels de Oliveira, Michel, Azambuja, Ana Paula de, Dunbar, Cynthia E, Olszewska, Malgorzata, Olivier, Emmanuel, Papapetrou, Eirini P, Giri, Neelam, Alter, Blanche P, Bonfim, Carmem M S, Wu, Colin O, Garcia-Manero, Guillermo, Savage, Sharon A, Young, Neal S, Colla, Simona, Calado, Rodrigo T

“…Telomere biology disorders (TBD), caused by pathogenic germline variants in telomere-related genes, present with multi-organ disease and a predisposition to…”
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Venous and arterial thrombosis in patients with VEXAS syndrome by Kusne, Yael, Ghorbanzadeh, Atefeh, Dulau-Florea, Alina, Shalhoub, Ruba, Alcedo, Pedro E., Nghiem, Khanh, Ferrada, Marcela A., Hines, Alexander, Quinn, Kaitlin A., Panicker, Sumith R., Ombrello, Amanda K., Reichard, Kaaren, Darden, Ivana, Goodspeed, Wendy, Durrani, Jibran, Wilson, Lorena, Olteanu, Horatiu, Lasho, Terra, Kastner, Daniel L., Warrington, Kenneth J., Mangaonkar, Abhishek, Go, Ronald S., Braylan, Raul C., Beck, David B., Patnaik, Mrinal M., Young, Neal S., Calvo, Katherine R., Casanegra, Ana I., Grayson, Peter C., Koster, Matthew J., Wu, Colin O., Kanthi, Yogendra, Patel, Bhavisha A., Houghton, Damon E., Groarke, Emma M.

“…•VTE is common in VEXAS syndrome, occurring in over 40% of patients with frequent recurrences; however, it is not associated with increased mortality.•Given…”
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