Search Results - "Shalev, Nurit"
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Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages
Published in Scientific reports (14-01-2021)“…Cannabis sativa is widely used for medical purposes and has anti-inflammatory activity. This study intended to examine the anti-inflammatory activity of…”
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Terpenoids and Phytocannabinoids Co-Produced in Cannabis Sativa Strains Show Specific Interaction for Cell Cytotoxic Activity
Published in Molecules (Basel, Switzerland) (21-08-2019)“…Mixtures of different phytocannabinoids are more active biologically than single phytocannabinoids. However, cannabis terpenoids as potential instigators of…”
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Effects of steam sterilization on reduction of fungal colony forming units, cannabinoids and terpene levels in medical cannabis inflorescences
Published in Scientific reports (07-07-2021)“…Medical cannabis (MC) production is a rapidly expanding industry. Over the past ten years, many additional phytocannabinoids have been discovered and used for…”
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Cannabis-Derived Compounds Cannabichromene and Δ9-Tetrahydrocannabinol Interact and Exhibit Cytotoxic Activity against Urothelial Cell Carcinoma Correlated with Inhibition of Cell Migration and Cytoskeleton Organization
Published in Molecules (Basel, Switzerland) (17-01-2021)“…contains more than 500 constituents, yet the anticancer properties of the vast majority of cannabis compounds remains unknown. We aimed to identify cannabis…”
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Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway
Published in Molecules (Basel, Switzerland) (01-11-2022)“…Ovarian cancer (OC) is the single most lethal gynecologic malignancy. Cannabis sativa is used to treat various medical conditions, and is cytotoxic to a…”
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Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply
Published in Scientific reports (25-04-2018)“…Transplantation of encapsulated islets can cure diabetes without immunosuppression, but oxygen supply limitations can cause failure. We investigated a…”
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Integrated transcriptome and cell phenotype analysis suggest involvement of PARP1 cleavage, Hippo/Wnt, TGF-β and MAPK signaling pathways in ovarian cancer cells response to cannabis and PARP1 inhibitor treatment
Published in Frontiers in genetics (2024)“…is utilized mainly for palliative care worldwide. Ovarian cancer (OC) is a lethal gynecologic cancer. A particular cannabis extract fraction ('F7') and the…”
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Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models
Published in Pharmaceuticals (Basel, Switzerland) (01-12-2022)“…Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD],…”
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Anti-Cancer Activity of Cannabis sativa Phytocannabinoids: Molecular Mechanisms and Potential in the Fight against Ovarian Cancer and Stem Cells
Published in Cancers (01-09-2022)“…Ovarian cancer (OC) is the most lethal gynecological malignancy, with about 70% of cases diagnosed only at an advanced stage. Cannabis sativa, which produces…”
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Anti-Cancer Activity of ICannabis sativa/I Phytocannabinoids: Molecular Mechanisms and Potential in the Fight against Ovarian Cancer and Stem Cells
Published in Cancers (01-09-2022)“…Ovarian cancer is the most lethal gynecological malignancy. Cancer stem cells have been implicated in tumor initiation, progression, and invasion, as well as…”
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Specific Compositions of Cannabis sativa Compounds Have Cytotoxic Activity and Inhibit Motility and Colony Formation of Human Glioblastoma Cells In Vitro
Published in Cancers (05-04-2021)“…Glioblastoma multiforme (GBM) is the most lethal subtype of glioma. is used for the treatment of various medical conditions. Around 150 phytocannabinoids have…”
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Non-Aqueous Isolation and Enrichment of Glandular Capitate Stalked and Sessile Trichomes from Cannabis sativa
Published in Journal of visualized experiments (12-05-2023)“…This paper presents a protocol for the convenient and high-throughput isolation and enrichment of glandular capitate stalked and sessile trichomes from…”
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Rhus coriaria L. (sumac) leaves harbour robust antimicrobial activity
Published in Journal of herbal medicine (01-09-2023)“…Rhus coriaria L. (sumac) has various medicinal properties, with the antibacterial activity of its fruit particularly well known. Building on earlier research,…”
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