Search Results - "Shakib, F."

Carbenes with Reduced Heteroatom Stabilization: A Computational Approach by Kassaee, M. Z, Shakib, F. A, Momeni, M. R, Ghambarian, M, Musavi, S. M

“…High-level DFT calculations, coupled with appropriate isodesmic reactions, are employed to investigate the effects of monoheteroatom substitution, cyclization,…”
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The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: experimental analysis of in silico substrate identification and implications in allergic responses by Furmonaviciene, R., Ghaemmaghami, A. M., Boyd, S. E., Jones, N. S., Bailey, K., Willis, A. C., Sewell, H. F., Mitchell, D. A., Shakib, F.

“…Summary Background The cysteine protease Der p 1 from the house dust mite Dermatophagoides pteronyssinus is one of the most potent allergens known. An…”
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The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: allergen-induced Th2 bias determined at the dendritic cell level by Ghaemmaghami, A. M., Gough, L., Sewell, H. F., Shakib, F.

“…Summary Background The proteolytic activity of the house dust mite allergen Der p 1 has recently been shown to bias Th cell subset development in favour of…”
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Density functional investigation of metal encapsulated X@C12Si8 heterofullerene (X=Li+, Na+, K+, Be2+, Mg2+, Ca2+, Al3+, Ga3+) by SHAKIB, F. A, MOMENI, M. R

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Proteolytic activity of the house dust mite allergen Der p 1 enhances allergenicity in a mouse inhalation model by Gough, L., Campbell, E., Bayley, D., Van Heeke, G., Shakib, F.

“…Summary Background We have recently demonstrated that intraperitoneal immunization of mice with proteolytically active Der p 1, the major house dust mite…”
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Allergen Recognition by Human Dendritic Cells: The Critical Role of DC-SIGN by Maghami, A. M. Ghaem, Emara, M, Shakib, F

“…[...]MR contributes only about 40-60% of the total Der p 1 uptake, suggesting the existence of other receptors. [...]the aim of this study was to identify…”
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The Role of Mannose Receptor in IgE Production in an in vivo Model of Cat Allergy by Ghaemmaghami, A.M, Emara, M, Martinez-Pomares, L, Shakib, F

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The proteolytic activity of the major dust mite allergen Der p 1 enhances the IgE antibody response to a bystander antigen by Gough, L., Sewell, H. F., Shakib, F.

“…Background We have recently demonstrated that immunization of mice with proteolytically active Der p 1, the major dust mite allergen, results in a significant…”
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Carbohydrate Moieties Mediate Allergen Uptake by Human Dendritic Cells by Ghaemmaghami, A.M, Emara, M, Shakib, F

“…Dendritic cells (DC) play a pivotal role in the initiation and maintenance of allergic responses…”
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Does pesticides pollution affect rice plants in the southern coastline of the Caspian Sea? by Mohammadian, M Afshar, Almasi, Z, Esmaeili, S, Shakib, F, Majidi-Shilsar, F, Shokrzadeh-Lamuki, M

“…Considering the increasing rice consumption in the world and also the excessive application of pesticides to increase production, an experiment was conducted…”
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A DFT study on pyridine-derived N-heterocyclic carbenes by Kassaee, M.Z., Shakib, F.A., Momeni, M.R., Ghambarian, M., Musavi, S.M.

“…To appreciate the chemistry of N-heterocyclic carbenes (NHCs), eight carbenic tautomers of pyridine (azacyclohexadienylidenes) are studied at…”
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Nonlinear dynamic modeling and analysis of borehole propagation for directional drilling by Shakib, M.F., Detournay, E., van de Wouw, N.

“…Boreholes with complex trajectories are drilled with the help of downhole rotary steerable systems. These robotic actuators, which are embedded in the…”
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Differential protein expression by dendritic cells from atopic and non-atopic individuals after stimulation by the major house dust mite allergen Der p 1 by Horlock, C, Shakib, F, Jones, N S, Sewell, H F, Ghaemmaghami, A M

“…Dendritic cells (DCs) are sentinels of the immune system and are known to play a key role in allergic responses. However, it is not clear how DCs that have…”
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The Role of Mannose Receptor in Allergen Recognition by Human Dendritic Cells (DC) by Ghaemmaghami, A.M, Shakib, F, Martinez-Pomares, L, Yang, C

“…Rationale It is thought that the mannose receptor (MR) is partially involved in the uptake of the major house dust mite allergen Der p 1 by human DC…”
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Human T cells that have been conditioned by the proteolytic activity of the major dust mite allergen Der p 1 trigger enhanced immunoglobulin E synthesis by B cells by Ghaemmaghami, A. M., Shakib, F.

“…Summary Background We have previously demonstrated that the proteolytic activity of Der p 1 selectively cleaves human CD25, the 55 kDa α subunit of the IL‐2…”
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From acyclic dialkylcarbene to the unsaturated cyclic heteroatom substituted ones: a survey of stability by Kassaee, M. Z., Ghambarian, M., Shakib, F. A., Momeni, M. R.

“…In regard to the worldwide interest in synthesis and application of stable carbenes, ab initio and DFT calculations (CCSD(T)/6‐311G*//QCISD/6‐31G* and…”
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The proteolytic activity of Der p 1 selectively enhances IgE synthesis: a link between allergenicity and cysteine protease activity by Shakib, F, Gough, L

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Controlling allergy with anti-idiotypic antibodies by Shakib, F

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The molecular basis of allergenicity: comparative analysis of the three dimensional structures of diverse allergens reveals a common structural motif by Furmonaviciene, R, Shakib, F

“…Background—Although a large number of allergens have been characterised, the structural, functional, and biochemical features that these molecules have in…”
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The use of phage-peptide libraries to define the epitope specificity of a mouse monoclonal anti-Der p 1 antibody representative of a major component of the human immunoglobulin E anti-Der p 1 response by FURMONAVICIENE, R, TIGHE, P. J, CLARK, M. R, SEWELL, H. F, SHAKIB, F

“…Background More than 80% of individuals who are sensitive to the dust mite Dermatophagoides pteronyssinus produce immunoglobulin (Ig) E antibodies to Der p 1,…”
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