Character of loosely and tightly bound human cerebral gangliosides and methods of preparatory extraction

The quantitative isolation of loosely and tightly bound gangliosides of human brain has been studied following various ways of extraction. Hot methanol extraction (Bogoch's method) gave a higher level of tightly bound gangliosides than by extraction with the Folch method. Both kinds of ganglios...

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Bibliographic Details
Published in:	Voprosy biokhimii mozga Vol. 10; p. 187
Main Authors:	Mkheian, E E, Shakhbatian, Sh L
Format:	Journal Article
Language:	Russian
Published:	Armenia (Republic) 1975
Subjects:	Brain Chemistry Gangliosides - isolation & purification Humans Methods
Online Access:	Get more information
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Summary:	The quantitative isolation of loosely and tightly bound gangliosides of human brain has been studied following various ways of extraction. Hot methanol extraction (Bogoch's method) gave a higher level of tightly bound gangliosides than by extraction with the Folch method. Both kinds of gangliosides were found to have the same fractional composition on thin layer chromatography on silicagel. A single extraction method of gangliosides giving high yields is proposed.
ISSN:	0507-2972