Search Results - "Shaker, Sara A."
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1
Effect of short-term high fat diet on resistin levels and expression of autophagy-related genes in the cartilage of male rats
Published in Scientific reports (12-09-2022)“…Obesity is a significant risk factor for the development of knee osteoarthritis (KOA). However, the precise molecular mechanisms linking obesity to OA remain…”
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2
The Anti-Obesity and Anti-Steatotic Effects of Chrysin in a Rat Model of Obesity Mediated through Modulating the Hepatic AMPK/mTOR/lipogenesis Pathways
Published in Molecules (Basel, Switzerland) (11-02-2023)“…Obesity is a complex multifactorial disease characterized by excessive adiposity, and is linked to an increased risk of nonalcoholic fatty liver disease…”
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3
Maternal and paternal obesity differentially reprogram the ovarian mitochondrial biogenesis of F1 female rats
Published in Scientific reports (19-09-2023)“…Obesity has harmful consequences on reproductive outcomes and the rapid increase in obesity is assumed to be influenced by epigenetics and trans-generation…”
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4
The pre-conception maternal exposure to Sofosbuvir affects the mitochondrial biogenesis in prenatal fetal tissues: Experimental study on rats
Published in Molecular medicine (Cambridge, Mass.) (06-06-2023)“…Hepatitis C virus (HCV) infection is a global public health problem and Egypt has the highest HCV prevalence worldwide. Hence, global efforts target to…”
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5
Cinnamaldehyde ameliorates STZ-induced diabetes through modulation of autophagic process in adipocyte and hepatic tissues on rats
Published in Scientific reports (02-05-2024)“…Type 2 diabetes mellitus is a worldwide public health issue. In the globe, Egypt has the ninth-highest incidence of diabetes. Due to its crucial role in…”
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6
Propolis-loaded nanostructured lipid carriers halt breast cancer progression through miRNA-223 related pathways: an in-vitro/in-vivo experiment
Published in Scientific reports (21-09-2023)“…The most frequent malignant tumor in women is breast cancer, and its incidence has been rising every year. Propolis has been used for its antibacterial,…”
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The Intergeneration Long-Lasting Consequences of Pre-Conceptional Exposure to Sofosbuvir on the Ovarian Tissues of F1 Offspring: Experimental Study on Rats
Published in International journal of molecular sciences (01-09-2023)“…Sofosbuvir (SOF), a nucleos(t)ide polymerase inhibitor, has been used during the past decade for mass treatment of viral hepatitis C in endemic countries like…”
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Direct-Acting Antiviral Drug Modulates the Mitochondrial Biogenesis in Different Tissues of Young Female Rats
Published in International journal of molecular sciences (01-11-2023)“…(1) Background: Hepatitis C virus (HCV) infection is endemic in Egypt, with the highest prevalence rate worldwide. Sofosbuvir (SOF) is a nucleos(t)ide analog…”
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9
Possible role of moderate exercise training in modulating gene expression of adipose tissue remodeling markers in obese male rats
Published in Sport sciences for health (01-12-2024)“…Purpose Obesity is a growing public health problem characterized by adipose tissue (AT) dysfunction that is associated with metabolic complications. Exercise…”
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10
Effect of superparamagnetic iron oxide nanoparticles on glucose homeostasis on type 2 diabetes experimental model
Published in Life sciences (1973) (15-03-2020)“…Evaluation of the anti-diabetic effect of superparamagnetic iron oxide nanoparticles (SPIONs) on Type 2 diabetic rats and compared their effect to metformin…”
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Astaxanthin ameliorated isoproterenol induced myocardial infarction via improving the mitochondrial function and antioxidant activity in rats
Published in Journal of biochemical and molecular toxicology (01-08-2024)“…The present study evaluated the cardioprotective effect of astaxanthin (ASX) against isoproterenol (ISO) induced myocardial infarction in rats via the pathway…”
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