Search Results - "Shakeel, Ilma"
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Thymoquinone, artemisinin, and thymol attenuate proliferation of lung cancer cells as Sphingosine kinase 1 inhibitors
Published in Biomedicine & pharmacotherapy (01-08-2024)“…Sphingosine-1-phosphate (S1P) formed via catalytic actions of sphingosine kinase 1 (SphK1) behaves as a pro-survival substance and activates downstream target…”
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The Molecular Blueprint for Chronic Obstructive Pulmonary Disease (COPD): A New Paradigm for Diagnosis and Therapeutics
Published in Oxidative medicine and cellular longevity (2023)“…The global prevalence of chronic obstructive pulmonary disease (COPD) has increased over the last decade and has emerged as the third leading cause of death…”
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Idiopathic pulmonary fibrosis: Pathophysiology, cellular signaling, diagnostic and therapeutic approaches
Published in Medicine in drug discovery (01-12-2023)“…Idiopathic pulmonary fibrosis (IPF) is a life-threatening and progressive interstitial lung disease. Healthy pulmonary tissues were replaced by an altered…”
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4
Polo-like Kinase 1 as an emerging drug target: structure, function and therapeutic implications
Published in Journal of drug targeting (07-02-2021)“…Polo-like kinase 1 (PLK1) is a conserved mitotic serine-threonine protein kinase, functions as a regulatory protein, and is involved in the progression of the…”
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Potential diagnostics and therapeutic approaches in COVID-19
Published in Clinica chimica acta (01-11-2020)“…•Insights into different diagnostic techniques of SARS-CoV-2 infection have been provided.•We highlighted the importance of different diagnosis methods of…”
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Investigating potential of cholic acid, syringic acid, and mangiferin as cancer therapeutics through sphingosine kinase 1 inhibition
Published in International journal of biological macromolecules (31-12-2023)“…The signaling of sphingosine kinase 1 (SphK1) and sphingosine-1-phosphate (S1P) regulates various diseases, including multiple sclerosis, atherosclerosis,…”
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