Search Results - "Shain, K.H"

A novel approach to study evolution of drug resistance and optimum therapy in multiple myeloma by Silva, A, Meads, M.B, Distler, A, Silva, M, Cubitt, C, Perez, L, Jacobson, T.W, Baz, R, Gatenby, R.A, Shain, K.H

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Oprozomib (OPZ) and Dexamethasone (DEX) in Patients (Pts) With Relapsed and/or Refractory Multiple Myeloma (RRMM): Updated Results From a Phase 1b/2, Multicenter, Open-Label Study by Prada, C.P, Shain, K.H, Voorhees, P, Gabrail, N, Abidi, M, Zonder, J, Boccia, R, Richardson, P.G, Neuman, L, Wong, H, Dixon, S, Hari, P

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The tumor microenvironment shapes hallmarks of mature B-cell malignancies by Shain, K H, Dalton, W S, Tao, J

“…B-cell tumorigenesis results from a host of known and unknown genetic anomalies, including non-random translocations of genes that normally function as…”
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The B-cell receptor orchestrates environment-mediated lymphoma survival and drug resistance in B-cell malignancies by Shain, K H, Tao, J

“…Specific niches within the lymphoma tumor microenvironment (TME) provide sanctuary for subpopulations of tumor cells through stromal cell–tumor cell…”
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Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma by Meads, M B, Fang, B, Mathews, L, Gemmer, J, Nong, L, Rosado-Lopez, I, Nguyen, T, Ring, J E, Matsui, W, MacLeod, A R, Pachter, J A, Hazlehurst, L A, Koomen, J M, Shain, K H

“…Multiple myeloma (MM) remains an incurable malignancy due, in part, to the influence of the bone marrow microenvironment on survival and drug response…”
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