Search Results - "Shailesh T"
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A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer’s disease
Published in Bioorganic & medicinal chemistry (01-05-2013)“…Monoamine oxidase (MAO) enzyme inhibition is a crucial target for the management of depression and Alzheimer disease and inhibitors of MAO are the most…”
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Strategies to Improve Insulin Delivery through Oral Route: A Review
Published in Current drug delivery (01-01-2022)“…Diabetes mellitus is found to be among the most suffered and lethal diseases for mankind. Diabetes mellitus type-1 is caused by the demolition of pancreatic…”
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Quality by design based development and optimization of novel gastroretentive floating osmotic capsules of clopidogrel bisulfate
Published in Journal of pharmaceutical investigation (15-05-2019)“…The aim of the present investigation was to develop and optimize gastroretentive floating osmotic formulation of clopidogrel bisulfate using risk based…”
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An Overview of a Biomarker in Breast Cancer
Published in International Journal of Pharmaceutical Investigation (01-10-2023)Get full text
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Quality System Requirements of Dietary Supplements: An Overview of 21 CFR Part 111
Published in International Journal of Pharmaceutical Investigation (01-10-2024)Get full text
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Annual Product Quality Review
Published in International journal of research in pharmaceutical sciences (15-04-2020)“…Annual Product Quality Review (APQR) is an estimation prepared according to the Current Goods Manufacturing Practice (CGMP) requirements of different…”
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Thermoreversible mucoadhesive ophthalmic in situ hydrogel: Design and optimization using a combination of polymers
Published in Acta pharmaceutica (Zagreb, Croatia) (01-09-2010)“…The purpose of the study was to develop an optimized thermoreversible in situ gelling ophthalmic drug delivery system based on Pluronic F 127, containing…”
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Preparation and Characterization of Self-Microemulsifying Drug Delivery System of Olmesartan Medoxomil for Bioavailability Improvement
Published in Journal of Pharmaceutics (01-01-2013)“…Olmesartan medoxomil (OLM) is an angiotensin II receptor blocker (ARB) antihypertensive agent administered orally that has absolute bioavailability of only 26%…”
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Formulation and Evaluation of Liquisolid Compacts for Olmesartan Medoxomil
Published in Journal of Drug Delivery (01-01-2013)“…Olmesartan medoxomil is an angiotensin type II receptor blocker, antihypertensive agent, administered orally. It is highly lipophilic (log P 5.5) and a poorly…”
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Randomised controlled trial for efficacy of unfractionated heparin (UFH) versus low molecular weight heparin (LMWH) in thrombo-prophylaxis
Published in Journal of the Association of Physicians of India (01-12-2013)“…To study if low dose Unfractionated heparin (UFH) is as effective and safe as Low-molecular weight heparin (LMWH) and also economical as a prophylactic agent…”
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Gastric floating matrix tablets: Design and optimization using combination of polymers
Published in Acta pharmaceutica (Zagreb, Croatia) (01-06-2008)“…The purpose of the present study was to develop an optimized gastric floating drug delivery system (GFDDS) containing domperidone as a model drug. Box-Behnken…”
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Preparation and evaluation of sublingual tablets of zolmitriptan
Published in International Journal of Pharmaceutical Investigation (01-01-2014)“…Aim: Zolmitriptan is a 5-HT receptor agonist (1B/1D). It is used in the acute treatment of migraine having low bioavailability about 40% orally due to hepatic…”
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Preparation and in vitro evaluation of ethylcellulose coated egg albumin microspheres of diltiazem hydrochloride
Published in Journal of young pharmacists (01-01-2010)“…The aim of the present investigation was to develop sustained release ethylcellulose-coated egg albumin microspheres of diltiazem hydrochloride (DH) to improve…”
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Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique
Published in ISRN pharmaceutics (01-01-2011)“…The present investigation describes the influence of the concentration of PEG 6000 as a melt binder and ratio of HPMC K4M : PVP on Zolpidem tartrate…”
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Formulation and Evaluation of Transdermal Patch of Repaglinide
Published in ISRN pharmaceutics (01-01-2011)“…Repaglinide has the half life of 1 hour, and bioavailability in the body is 56% due to first-pass metabolism. The total daily dose of Repaglinide is 16 mg…”
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Development and validation of the liquid chromatography-tandem mass spectrometry method for quantitative estimation of candesartan from human plasma
Published in Pharmaceutical Methods (01-04-2011)“…Introduction: A simple and sensitive liquid chromatography-tandem mass spectrometry method was developed and validated for estimation of candesartan in human…”
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Bedsore and strategies for preventing and treating the bedsore
Published in International journal of research in pharmaceutical sciences (20-01-2021)“…The best recognized and also the most widespread example of tissue necrosis is bedsore. A bedsore is localized damage to the skin and other underlying tissue,…”
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Formulation and optimisation of raft-forming chewable tablets containing H 2 antagonist
Published in International Journal of Pharmaceutical Investigation (01-10-2012)“…Purpose: The purpose of this research work was to formulate raft-forming chewable tablets of H 2 antagonist (Famotidine) using a raft-forming agent along with…”
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Formulation and optimisation of raft-forming chewable tablets containing H2 antagonist
Published in International Journal of Pharmaceutical Investigation (01-10-2012)“…The purpose of this research work was to formulate raft-forming chewable tablets of H2 antagonist (Famotidine) using a raft-forming agent along with an…”
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