Search Results - "Shaikh, Aarif L."

Biodistribution and subcellular localization of an unnatural boron-containing amino acid (cis-ABCPC) by imaging secondary ion mass spectrometry for neutron capture therapy of melanomas and gliomas by Chandra, Subhash, Barth, Rolf F, Haider, Syed A, Yang, Weilian, Huo, Tianyao, Shaikh, Aarif L, Kabalka, George W

“…The development of new boron-delivery agents is a high priority for improving the effectiveness of boron neutron capture therapy. In the present study,…”
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Evaluation of unnatural cyclic amino acids as boron delivery agents for treatment of melanomas and gliomas by Barth, Rolf F., Kabalka, George W., Yang, Weilian, Huo, Tianyao, Nakkula, Robin J., Shaikh, Aarif L., Haider, Syed A., Chandra, Subhash

“…Unnatural cyclic amino acids (UNAAs) are a new class of boron delivery agents that are in a pre-clinical stage of evaluation. In the present study, the…”
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Peptide peak intensities enhanced by cysteine modifiers and MALDI TOF MS by Zabet-Moghaddam, Masoud, Shaikh, Aarif L., Niwayama, Satomi

“…Two cysteine‐specific modifiers we reported previously, N‐ethyl maleimide (NEM) and iodoacetanilide (IAA), have been applied to the labeling of cysteine…”
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Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models by Yang, Weilian, Barth, Rolf F., Huo, Tianyao, Kabalka, George W., Shaikh, Aarif L., Haider, Syed A., Chandra, Subhash

“…The present study was undertaken to evaluate the effects of l-DOPA pre-loading on the uptake of BPA using the F98 rat glioma and the murine B16 melanoma…”
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Synthesis of d-labeled and unlabeled benzoyloxysuccinimides and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry by Zabet-Moghaddam, Masoud, Shaikh, Aarif L., Jones, Lauren B., Niwayama, Satomi

“…D 5-labeled and unlabeled benzoyloxysuccinimides that covalently react with amino groups have been synthesized and applied to quantitative analysis of peptides…”
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Boronated unnatural cyclic amino acids as potential delivery agents for neutron capture therapy by Kabalka, George W., Shaikh, Aarif L., Barth, Rolf F., Huo, Tianyao, Yang, Weilian, Gordnier, Pamela M., Chandra, Subhash

“…Boron delivery characteristics of cis and trans isomers of a boronated unnatural amino acid, 1-amino-3-boronocyclopentanecarboxylic acid (ABCPC) were tested in…”
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Synthesis of d-labeled and unlabeled ethyl succinic anhydrides and application to quantitative analysis of peptides by isotope differential mass spectrometry by Niwayama, Satomi, Zabet-Moghaddam, Masoud, Kurono, Sadamu, Kattanguru, Pullaiah, Shaikh, Aarif L.

“…[Display omitted] Ethyl succinic anhydride and its d5-labeled version have been synthesized and applied to quantitative analysis of peptides in combination…”
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A Novel Asymmetric Synthesis of 3-(1H-Pyrrol-1-yl)-Substituted β-Lactams via a Bismuth Nitrate-Catalyzed Reaction by Shaikh, Aarif L., Banik, Bimal K.

“…The reaction of racemic α‐keto β‐lactams 5a–5c with the commercially available chiral compound trans‐4‐hydroxy‐L‐proline (6) in the presence of a catalytic…”
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An Efficient Synthesis of Optically Active trans-(3R,4R)-3-Acetoxy-4-aryl-1-(chrysen-6-yl)azetidin-2-ones Using (+)-Car-3-ene as a Chiral Auxiliary by Shaikh, Aarif L., Esparza, Orlando, Banik, Bimal K.

“…An efficient enantioselective synthesis of 3‐acetoxy trans‐β‐lactams 7a and 7b via [2+2] cycloaddition reactions of imines 4a and 4b, derived from a polycyclic…”
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Biodistribution and Subcellular Localization of an Unnatural Boron-Containing Amino Acid by Chandra, Subhash, Barth, Rolf F, Haider, Syed A, Yang, Weilian, Huo, Tianyao, Shaikh, Aarif L, Kabalka, George W

“…The development of new boron-delivery agents is a high priority for improving the effectiveness of boron neutron capture therapy. In the present study,…”
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γ-Heteroatom directed stereocontrolled Staudinger cycloaddition reaction of vinylketenes and imines by Shaikh, Aarif L., Puranik, Vedavati G., Deshmukh, A.R.A.S.

“…Vinylketenes possessing a γ-heteroatom, on Staudinger cycloaddition reaction with imines, gave trans-3-vinyl-β-lactams in very good yields. The vinyl side…”
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Synthesis of cis bis-β-lactams via Staudinger cycloaddition reaction using C2-symmetric 1,2-diamines by Shaikh, Aarif L., Puranik, Vedavati G., Deshmukh, A.R.A.S.

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Benzannulated Cyclooctanol Derivatives by Samarium Diiodide Induced Intramolecular Carbonyl-Alkene Coupling - Scope, Limitations, Stereoselectivity by Reißig, Hans-Ulrich, Khan, Faiz Ahmed, Czerwonka, Regina, Dinesh, Chimmanamada U., Shaikh, Aarif L., Zimmer, Reinhold

“…A series of γ‐oxo esters 27–34 was prepared from methyl 2‐silyloxycyclopropanecarboxylates 1–9 as key building blocks in a flexible modular synthesis. Their…”
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Synthesis of cis bis-β-lactams via Staudinger cycloaddition reaction using C 2-symmetric 1,2-diamines by Shaikh, Aarif L., Puranik, Vedavati G., Deshmukh, A.R.A.S.

“…An efficient stereoselective synthesis of bis-β-lactams via cycloaddition reaction (Staudinger reaction) of ketenes with bisimines derived from C 2-symmetric…”
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