Search Results - "Shahzad, Khawar Ali"

A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide-Autoreactive CD4 + and CD8 + T Cells by Wan, Xin, Pei, Weiya, Shahzad, Khawar Ali, Zhang, Lei, Song, Shilong, Jin, Xiaoxiao, Wang, Limin, Zhao, Chen, Shen, Chuanlai

“…In this study, a tolerogenic artificial APC (TaAPC) was developed to directly and selectively modulate myelin-autoreactive CD4 and CD8 T cells in the myelin…”
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The roles of focal adhesion and cytoskeleton systems in fluid shear stress-induced endothelial cell response by ALI SHAHZAD, KHAWAR, QIN, ZHONGJIE, LI, YAN, XIA, DELIN

“…Focal adhesions are polyproteins linked to extracellular matrix and cytoskeleton, which play an important role in the process of transforming force signals…”
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Immunomodulatory effect of mesenchymal stem cells‐derived extracellular vesicles to modulate the regulatory T cells and Th1/Th2 imbalance in peripheral blood mononuclear cells of patients with allergic rhinitis by Wang, Zhao, Shahzad, Khawar Ali, Li, Xuran, Cai, Boyu, Xu, Maoxiang, Li, Jiaojiao, Tan, Fei

“…Mesenchymal stem cell‐derived extracellular vesicles (MSC‐EVs) have shown promising immunomodulatory capabilities for a variety of clinical conditions…”
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Collective influence of substrate chemistry with physiological fluid shear stress on human umbilical vein endothelial cells by Li, Yan, Qin, Zhongjie, Zhou, Lin, Shahzad, Khawar Ali, Xia, Delin

“…In the treatment of cardiovascular diseases, vascular scaffold materials play an extremely important role. The appropriate substrate chemistries and 15…”
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Immunomodulatory effect of PLGA-encapsulated mesenchymal stem cells-derived exosomes for the treatment of allergic rhinitis by Shahzad, Khawar Ali, Wang, Zhao, Li, Xuran, Li, Jiaojiao, Xu, Maoxiang, Tan, Fei

“…Allergic rhinitis (AR) is an upper airway inflammatory disease of the nasal mucosa. Conventional treatments such as symptomatic pharmacotherapy and…”
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Therapeutic potential of EVs loaded with CB2 receptor agonist in spinal cord injury via the Nrf2/HO-1 pathway by Shaikh, Imran Ibrahim, Bhandari, Ramesh, Singh, Shekhar, Zhu, Xu, Ali Shahzad, Khawar, Shao, Chuxiao, Cheng, Liming, Xiao, Jian

“…Spinal cord injury (SCI) poses a challenge due to limited treatment options. Recently, the effect and mechanism of Exo-loaded cannabinoid receptor type 2 (CB2)…”
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GelMA/PEDOT:PSS Composite Conductive Hydrogel-Based Generation and Protection of Cochlear Hair Cells through Multiple Signaling Pathways by Tan, Fei, Li, Xuran, Li, Xiao, Xu, Maoxiang, Shahzad, Khawar Ali, Hou, Lei

“…Recent advances in cochlear implantology are exemplified by novel functional strategies such as bimodal electroacoustic stimulation, in which the patient has…”
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Signaling pathways activated and regulated by stem cell-derived exosome therapy by Li, Ding, Li, Danni, Wang, Zhao, Li, Jiaojiao, Shahzad, Khawar Ali, Wang, Yanhong, Tan, Fei

“…Stem cell-derived exosomes exert comparable therapeutic effects to those of their parental stem cells without causing immunogenic, tumorigenic, and ethical…”
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A Combination Strategy for Construction of Peptide-β2m-H-2K b Single Chain with Overlap Extension PCR and One-Step Cloning by Xu, Tao, Li, Xiaoe, Wu, You, Shahzad, Khawar Ali, Wang, Wei, Zhang, Lei, Shen, Chuanlai

“…The time-consuming and high-cost preparation of soluble peptide-major histocompatibility complexes (pMHC) currently limits their wide uses in monitoring…”
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Direct modulation of myelin-autoreactive CD4 + and CD8 + T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules by Pei, Weiya, Wan, Xin, Shahzad, Khawar Ali, Zhang, Lei, Song, Shilong, Jin, Xiaoxiao, Wang, Limin, Zhao, Chen, Shen, Chuanlai

“…Numerous nanomaterials have been reported in the treatment of multiple sclerosis or experimental autoimmune encephalomyelitis (EAE). But most of these…”
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Frequency and reactivity of antigen-specific T cells were concurrently measured through the combination of artificial antigen-presenting cell, MACS and ELISPOT by Shen, Chuanlai, Xu, Tao, Wu, You, Li, Xiaoe, Xia, Lingzhi, Wang, Wei, Shahzad, Khawar Ali, Zhang, Lei, Wan, Xin, Qiu, Jie

“…Conventional peptide-major histocompatibility complex (pMHC) multimer staining, intracellular cytokine staining, and enzyme-linked immunospot (ELISPOT) assay…”
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On-target and direct modulation of alloreactive T cells by a nanoparticle carrying MHC alloantigen, regulatory molecules and CD47 in a murine model of alloskin transplantation by Shahzad, Khawar Ali, Wan, Xin, Zhang, Lei, Pei, Weiya, Zhang, Aifeng, Younis, Muhammad, Wang, Wei, Shen, Chuanlai

“…Biomimetic nanoparticles have been reported as immune modulators in autoimmune diseases and allograft rejections by numerous researchers. However, most of the…”
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An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8 + T Cells by Wang, Wei, Shahzad, Khawar Ali, Li, Miaochen, Zhang, Aifeng, Zhang, Lei, Xu, Tao, Wan, Xin, Shen, Chuanlai

“…Selectively depleting the pathogenic T cells is a fundamental strategy for the treatment of allograft rejection and autoimmune disease since it retains the…”
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A Combination Strategy for Construction of Peptide-β2m-H-2Kb Single Chain with Overlap Extension PCR and One-Step Cloning by Tao Xu, Xiaoe Li, You Wu, Khawar Ali Shahzad, Wei Wang, Lei Zhang, Chuanlai Shen

“…The time-consuming and high-cost preparation of soluble peptide-major histocompatibility complexes (pMHC) currently limits their wide uses in monitoring…”
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WITHDRAWN: Long non-coding RNA RP5-821D11.7 promotes proliferation, migration, and epithelial-mesenchymal transition in glioma and glioma stem-like cells by Younis, Muhammad, Shaikh, Sana, Shahzad, Khawar Ali

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Evaluating the potential of Abelmoschus esculentus, Solanum melongena, and Capsicum annuum spp. for nutrient and microbial reduction from wastewater in hybrid constructed wetland by Abbasi, Haq Nawaz, Ahmad, Waqar, Shahzad, Khawar Ali, Lu, Xiwu

“…Utilizing engineered wetlands for the cultivation of vegetables can help to overcome the problems of water and food scarcity. These wetlands are primarily…”
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Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury by Li, Jiaojiao, Li, Xuran, Li, Xiangyu, Liang, Zhanping, Wang, Zhao, Shahzad, Khawar Ali, Xu, Maoxiang, Tan, Fei

“…Traumatic brain injury poses serious physical, psychosocial, and economic threats. Although systemic administration of stem cell-derived exosomes has recently…”
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Amrubicin encapsulated PLGA NPs inhibits the PI3K/AKT signaling pathway by activating PTEN and inducing apoptosis in TMZ-resistant Glioma by Younis, Muhammad, Shaikh, Sana, Shahzad, Khawar Ali, Tan, Fei, Wang, Zhao, Lashari, Mushtaq Hussain

“…Glioblastoma (GBM) remains a challenging malignancy due to its aggressive nature and the lack of efficacious therapeutic interventions. Nanotechnology-based…”
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Long non-coding RNA RP5-821D11.7 promotes proliferation, migration, and epithelial-mesenchymal transition in glioma and glioma stem-like cells by Younis, Muhammad, Shaikh, Sana, Shahzad, Khawar Ali

“…Long noncoding RNA (lncRNA) has been recently revealed as a main regulatory molecule, which implicates many cellular functions. Studies showed that lncRNA…”
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Paracrine release of IL-2 and anti-CTLA-4 enhances the ability of artificial polymer antigen-presenting cells to expand antigen-specific T cells and inhibit tumor growth in a mouse model by Zhang, Lei, Wang, Limin, Shahzad, Khawar Ali, Xu, Tao, Wan, Xin, Pei, Weiya, Shen, Chuanlai

“…Accumulating evidence indicates that bead-based artificial antigen-presenting cells (aAPCs) are a powerful tool to induce antigen-specific T cell responses in…”
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