Search Results - "Shahi, Nerina"
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5‑Methoxyisatin N(4)-Pyrrolidinyl Thiosemicarbazone (MeOIstPyrd) Restores Mutant p53 and Inhibits the Growth of Skin Cancer Cells, In Vitro
Published in ACS omega (05-09-2023)“…A series of novel thiosemicarbazone derivatives containing 5-methoxy isatin were designed and synthesized with modification on N(4) position. Derivatives…”
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Anticancer potential of 3-hydroxypyridine-2-carboxaldehyde N(4)-methyl and pyrrolidinylthiosemicarbazones and their Zn(II) complexes in different cancers via targeting MAPK superfamily signaling pathway
Published in Results in Chemistry (01-01-2021)“…Schematic representation of mechanism of action of HHyPyPyrd on cancer cell proliferation. [Display omitted] Zinc(II) complexes of 3-hydroxy-2-formylpyridine…”
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Isaria tenuipes Peck, an entomopathogenic fungus from Darjeeling Himalaya: Evaluation of in-vitro antiproliferative and antioxidant potential of its mycelium extract
Published in BMC complementary and alternative medicine (11-06-2020)“…Isaria tenuipes is one of the potent species in the members of the genus Isaria, which is well reported to possess multiple bioactive substances of therapeutic…”
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2-Pyridineformamide N(4)-ring incorporated thiosemicarbazones inhibit MCF-7 cells by inhibiting JNK pathway
Published in Bioorganic & medicinal chemistry letters (01-07-2019)“…[Display omitted] In an effort to develop a more potent anticancer therapeutic agent, a series of 2-pyridineformamide thiosemicarbazones (R = H, 4-CH3, 5-F,…”
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Knockdown of CSNK2ß suppresses MDA-MB231 cell growth, induces apoptosis, inhibits migration and invasion
Published in EXCLI journal (07-09-2020)“…Breast cancer is the most common cancer among women worldwide. Among different types of breast cancer known, treatment of triple-negative breast cancer is a…”
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CRISPR/Cas9 System: A Bacterial Tailor for Genomic Engineering
Published in Genetics research international (01-01-2018)“…Microbes use diverse defence strategies that allow them to withstand exposure to a variety of genome invaders such as bacteriophages and plasmids. One such…”
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