Search Results - "Shaheen, Sameerah"

Simvastatin mitigates diabetic nephropathy by upregulating farnesoid X receptor and Nrf2/HO-1 signaling and attenuating oxidative stress and inflammation in rats by Hasan, Iman H., Shaheen, Sameerah Y., Alhusaini, Ahlam M., Mahmoud, Ayman M.

“…Diabetic nephropathy is one of the complications of diabetes that affects the kidney and can result in renal failure. The cholesterol-lowering drug simvastatin…”
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Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer by Shaheen, Sameerah, Ahmed, Mehreen, Lorenzi, Federica, Nateri, Abdolrahman S.

“…Colorectal cancers (CRCs) form a disorganized hierarchy of heterogeneous cell populations on which current chemotherapy regimens fail to exert their…”
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Anti-Proliferative Activity of Glucagon-Like Peptide-1 Receptor Agonist on Obesity-Associated Breast Cancer: The Impact on Modulating Adipokines’ Expression in Adipocytes and Cancer Cells by Alanteet, Alaa A., Attia, Hala A., Shaheen, Sameerah, Alfayez, Musaed, Alshanawani, Bisher

“…Obesity is associated with high risk and poor prognosis of breast cancer (BC). Obesity promotes BC cells proliferation via modulating the production of…”
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Association of cyclin-dependent kinase inhibitor 2B antisense RNA 1 gene expression and rs2383207 variant with breast cancer risk and survival by Kattan, Shahad W, Hobani, Yahya H, Shaheen, Sameerah, Mokhtar, Sara H, Hussein, Mohammad H, Toraih, Eman A, Fawzy, Manal S, Abdalla, Hussein Abdelaziz

“…The expression signature of deregulated long non-coding RNAs (lncRNAs) and related genetic variants is implicated in every stage of tumorigenesis, progression,…”
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Vitamin C stimulates RNA expression of human gingival fibroblasts proliferation and adhesion in cigarette smokers: An in vitro study by Alyami, Ruaa, Alshehri, Fahad Ali, Al Jasser, Reham, Shaheen, Sameerah, Mahmood, Amer, Elsafadi, Mona Ahmed

“…Smoking and the severity of periodontal disease have long been associated. In Saudi Arabia, tobacco smoking is rising, contributing to the increased demand for…”
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TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton by Alfayez, Musaad, Kassem, Moustapha, Dawud, Raed Abu, Mahmood, Amer, Shaheen, Sameerah, Hashmi, Jamil Amjad, Iqbal, Zafar, Atteya, Muhammad, Mubarak, Mohammed, Almalki, Sami, Manikandan, Muthurangan, Elsafadi, Mona, Alajez, Nehad M.

“…TGFβ is a potent regulator of several biological functions in many cell types, but its role in the differentiation of human bone marrow-derived skeletal stem…”
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Chitosan nanoparticles as a promising candidate for liver injury induced by 2-nitropropane: Implications of P53, iNOS, VEGF, PCNA, and CD68 pathways by Shaheen, Sameerah, Arafah, Maha M, Alshanwani, Aliah R, Fadda, Laila Mohammed, Alhusaini, Ahlam M, Ali, Hanaa M, Hasan, Iman H, Hagar, Hanan, Alharbi, Fatima MB, AlHarthii, Alaa

“…The current article was designed to assess the role of chitosan nanoparticles (CNPs) in the management of hepatic injury induced by the hepatocarcinogen…”
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Manipulation of Quercetin and Melatonin in the Down-Regulation of HIF-1α, HSP-70 and VEGF Pathways in Rat’s Kidneys Induced by Hypoxic Stress by Alshanwani, Aliah R., Shaheen, Sameerah, Faddah, Laila M., Alhusaini, Ahlam M., Ali, Hanaa M., Hasan, Iman, Hagar, Hanan, Ahmed, Raeesa, Alharbi, Fatima M. B., AlHarthii, Alaa

“…Hypoxia may lead to inflammatory responses by numerous signaling pathways. This investigation intended to inspect the defensive role of Quercetin (Quer) and/…”
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Association of microRNA 17 host gene variant (rs4284505) with susceptibility and severity of systemic lupus erythematosus by Abdel‐Gawad, Abdelhady R., Shaheen, Sameerah, Babteen, Nouf A., Toraih, Eman A., Elshazli, Rami M., Fawzy, Manal S., Gouda, Nawal S.

“…Objective MicroRNAs are large family clusters of small noncoding RNAs that implicated in genetic and epigenetic regulation of several immunological processes…”
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Menstrual Cycle Changes after the COVID-19 Vaccine: A Cross-sectional Study in Saudi Arabia by Alshammari, Hessah Fahan, Alrabiah, Amal Humod, Shaheen, Sameerah Yaseen, Mazi, Sarah Ismail, Aljasser, Rakia Suliman

“…Objective: Various side effects of the COVID-19 vaccine, such as fatigue, have been reported. However, there has been a recent increase in reports of menstrual…”
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A promising antifibrotic drug, pyridoxamine attenuates thioacetamide-induced liver fibrosis by combating oxidative stress, advanced glycation end products, and balancing matrix metalloproteinases by Alshanwani, Aliah R., Hagar, Hanan, Shaheen, Sameerah, Alhusaini, Ahlam M., Arafah, Maha M., Faddah, Laila M., Alharbi, Fatima MB, Sharma, Arun K., Fayed, Amel, Badr, Amira M.

“…Liver fibrosis is a common chronic hepatic disease. This study was done to examine the effect of pyridoxamine against thioacetamide-induced hepatic fibrosis…”
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Proliferation of bovine myoblast by LncPRRX1 via regulation of the miR-137/CDC42 axis by Zhang, Wenzhen, Sun, Bing, Zhao, Yanqing, Raza, Sayed Haidar Abbas, Li, Yishu, Wang, Jianfang, Ma, Xinhao, Almohaimeed, Hailah M., Shaheen, Sameerah, Al-Sarraj, Faisal, Albiheyri, Raed, Mei, Chugang, Zan, Linsen

“…Noncoding RNAs, such as long noncoding RNAs (lncRNAs), are abundant in livestock. Many lncRNAs that affect the growth rate of livestock have been identified in…”
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Evaluating the Transformative Impact of Online Education on Medical Student Learning Outcomes by Alshammari, Hessah, Shaheen, Sameerah, Mahmoud, Shimaa, Al-Rabiah, Amal, Alyahya, Khaleel

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Cytotoxicity, in silico predictions and molecular studies for androstane heterocycle compounds revealed potential antitumor agent against lung cancer cells by Tantawy, Mohamed A., Shaheen, Sameerah, Kattan, Shahad W., Alelwani, Walla, Barnawi, Ibrahim O., Elmgeed, Gamal A., Nafie, Mohamed S.

“…The IL6/JAK2/STAT3 axis dysregulation and the related downstream pathways are a major contributor to the progression of non-small-cell lung carcinoma (NSCLC)…”
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Cyanocobalamin and/or calcitriol mitigate renal damage-mediated by tamoxifen in rats: Implication of caspase-3/NF-κB signaling pathways by Alshanwani, Aliah R., Mohamed, Azza M., Faddah, Laila M., Shaheen, Sameerah, Arafah, Maha M., Hagar, Hanan, Alhusaini, Ahlam M., Alharbi, Fatima M.B., AlHarthii, Alaa, Badr, Amira M.

“…Tamoxifen (TAMO) is a chemotherapeutic drug used for the treatment of breast cancer. Nevertheless, there is a lack of information available in regarding its…”
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Non-coding RNAs as key players in the neurodegenerative diseases: Multi-platform strategies and approaches for exploring the Genome’s dark matter by Almohaimeed, Hailah M., Assiri, Rasha, Althubaiti, Eman Hillal, Aggad, Waheeb S., Shaheen, Sameerah, Shaheen, Marwa Y., Batarfi, Munirah A., Alharbi, Nada Abdullah, Alshehri, Areej Mohammed, Alkhudhairy, Basal sulaiman M.

“…A growing amount of evidence in the last few years has begun to unravel that non-coding RNAs have a myriad of functions in gene regulation. Intensive…”
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PUNISHER rs12318065 C>A transversion: a putative somatic driver mutation for poor prognosis in colon cancer by Shaheen, Sameerah, Alshammari, Eida M, Mokhtar, Sara H, Alshanwani, Aliah R, Toraih, Eman A, Ibrahiem, Afaf T, Fawzy, Manal S, Maher, Shymaa Ahmed

“…Colon cancer (CC) remains one of the leading causes of cancer death worldwide. Several mutations/polymorphisms have been implicated in CC development and/or…”
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Roles & mechanisms of nanog-mediated drug resistance in human colorectal cells by Shaheen, Sameerah

“…NANOG is a transcription factor that functions as a central regulator of pluripotency and determines the cell fate in embryonic stem cells (ESCs). Dr Nateri’s…”
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The beneficial effects of antioxidants combination on cardiac injury induced by tetrachloromethane by Alshanwani, Aliah R., Faddah, Laila M., Hagar, Hanan, Alhusaini, Ahlam M., Shaheen, Sameerah, Mohammad, Raeesa A., Alharbi, Fatima M. B., AlHarthii, Alaa, Badr, Amira M.

“…The purpose of this research was to evaluate the efficacy of carsil (CAR) either alone or in combination with α-tocopherol (α-TOCO) and/or turmeric (TUMR)…”
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Expression of oncolong noncoding RNA taurine-upregulated gene-1 in colon cancer: A clinical study supported by in silico analysis by Abushouk, Abdelrahman, Kattan, Shahad, Ahmedah, Hanadi, Baothman, Eshrag, Shaheen, Sameerah, Toraih, Eman, Fawzy, Manal

“…Context: Recent studies confirmed that dysregulation of long noncoding RNAs (lncRNAs) is a potential contributor to the development and progression of colon…”
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