Search Results - "Shahanawaz, Jiwani"
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PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy
Published in Cardiovascular research (01-11-2018)“…Abstract Aims Inhibition of proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a novel therapy to treat hypercholesterolaemia and related…”
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Endothelin-1 upregulation mediates aging-related cardiac fibrosis
Published in Journal of molecular and cellular cardiology (01-03-2015)“…Abstract Endothelin-1 (ET-1) plays a major role in regulating myocardial fibrosis in several pathological conditions, such as hypertension and diabetes. Aging…”
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3
TIMP-1 Inhibits Apoptosis in Lung Adenocarcinoma Cells via Interaction with Bcl-2
Published in PloS one (14-09-2015)“…Tissue inhibitors of metalloproteinases (TIMPs) are multifaceted molecules that exhibit properties beyond their classical proteinase inhibitory function…”
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4
Chlamydia trachomatis Tarp Harbors Distinct G and F Actin Binding Domains That Bundle Actin Filaments
Published in Journal of Bacteriology (01-02-2013)“…All species of Chlamydia undergo a unique developmental cycle that transitions between extracellular and intracellular environments and requires the capacity…”
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5
Identification of Components of the Host Type IA Phosphoinositide 3-Kinase Pathway That Promote Internalization of Listeria monocytogenes
Published in Infection and Immunity (01-03-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cross-talk between LOX-1 and PCSK9 in vascular tissues
Published in Cardiovascular research (01-09-2015)“…Lectin-like ox-LDL receptor-1 (LOX-1) plays an important role in inflammatory diseases, such as atherosclerosis. Proprotein convertase subtilisin/kexin type 9…”
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Corrigendum to: PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy
Published in Cardiovascular research (29-06-2022)Get full text
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Corrigendum to: PCSK9 regulates expression of scavenger receptors and ox-LDL uptake in macrophages
Published in Cardiovascular research (22-06-2022)Get full text
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Rapid Clinical Mutation Screening for AML Using the Genexus Platform
Published in Blood (02-11-2023)“…Introduction: The promise of “precision medicine” is using therapeutic agents matched to the inferred biology of a patient's particular disease. In acute…”
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Fine-needle aspiration cytology of epithelioid malignant peripheral nerve sheath tumor: A case report and review of the literature
Published in Diagnostic cytopathology (01-03-2016)“…The epithelioid variant of malignant peripheral nerve sheath tumor (eMPNST) is an extremely rare soft tissue neoplasm comprising less than 5% of all MPNSTs. It…”
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Phase 2 trial of TRC102 (methoxyamine HCl) with temozolomide (TMZ) in patients with granulosa cell ovarian cancer
Published in Journal of clinical oncology (01-06-2023)“…5564 Background: TRC102 is a novel small molecule that binds to reactive aldehyde created in apurinic/apyrimidinic (AP) sites, inhibiting base excision repair…”
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Epigenetic Silencing of Death-Associated Protein Kinase Gene May Promote Mesenteric Metastasis in Primary Ovarian Cancer
Published in American journal of clinical pathology (01-09-2016)Get full text
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13
Biphenotypic plasma cell myeloma: two cases of plasma cell neoplasm with a coexpression of kappa and lambda light chains
Published in International journal of clinical and experimental pathology (01-01-2015)“…Plasma cell neoplasm (PCM) is a medullary and extra medullary proliferation of clonal plasma cells that occurs due to accidental translocation of…”
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14
Blood-based detection of actionable alterations from NCI-MATCH patients with no tissue results
Published in Journal of clinical oncology (01-06-2022)“…3035 Background: The National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH) multi-arm phase II clinical trial tested tumor tissue from…”
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Inflammatory Myofibroblastic Tumor of the Lung. A Rare Primary Lung Cancer
Published in American journal of respiratory and critical care medicine (01-10-2017)“…Discussion IMT is a clonal proliferation of myofibroblasts with ALK-1 overexpression mainly of ALK tropomyosin (TPM)-3, ALK-TPM4,…”
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Epigenetic Silencing of Death-Associated Protein Kinase Gene May Promote Mesenteric Metastasis in Primary Ovarian Cancer
Published in American journal of clinical pathology (01-01-2016)Get full text
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17
Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors
Published in Cancer chemotherapy and pharmacology (01-03-2024)“…Purpose Talazoparib is an inhibitor of the poly (ADP-ribose) polymerase (PARP) family of enzymes and is FDA-approved for patients with (suspected) deleterious…”
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Evaluation of a Rapid Automated Next Generation Sequencing Assay for Precision Medicine in Acute Myeloid Leukemia
Published in Blood (23-11-2021)“…Background: In the last decade there have been significant advances in diagnosing and classifying adult acute myeloid leukemia (AML) based on genomic…”
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Abstract 3015: Applications of immunohistochemistry in characterization of patient derived xenograft models
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Background: Well characterized patient derived xenograft models (PDX) are becoming the preferred pre-clinical tool in translational cancer research…”
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Abstract 3139: Study of tumor heterogeneity and subclonality in primary pancreatic and metastatic sites from rapid autopsy patients in PDMR
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Background: A major set of preclinical models derived from specimens acquired from rapid autopsy patients in the National Cancer Institute…”
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