Search Results - "Shaha, Suyog"

Strategies to improve the EPR effect: A mechanistic perspective and clinical translation by Ikeda-Imafuku, Mayumi, Wang, Lily Li-Wen, Rodrigues, Danika, Shaha, Suyog, Zhao, Zongmin, Mitragotri, Samir

“…Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance their efficacy and to reduce their adverse effects. These efforts…”
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Locoregional drug delivery for cancer therapy: Preclinical progress and clinical translation by Shaha, Suyog, Rodrigues, Danika, Mitragotri, Samir

“…Systemic drug delivery is the current clinically preferred route for cancer therapy. However, challenges associated with tumor localization and off-tumor toxic…”
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Extracellular matrix degrading enzyme with stroma-targeting peptides enhance the penetration of liposomes into tumors by Ikeda-Imafuku, Mayumi, Gao, Yongsheng, Shaha, Suyog, Wang, Lily Li-Wen, Park, Kyung Soo, Nakajima, Mayuka, Adebowale, Omokolade, Mitragotri, Samir

“…Various anti-tumor nanomedicines have been developed based on the enhanced permeability and retention effect. However, the dense extracellular matrix (ECM) in…”
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Preclinical characterization of macrophage-adhering gadolinium micropatches for MRI contrast after traumatic brain injury in pigs by Wang, Lily Li-Wen, Gao, Yongsheng, Chandran Suja, Vineeth, Boucher, Masen L, Shaha, Suyog, Kapate, Neha, Liao, Rick, Sun, Tao, Kumbhojkar, Ninad, Prakash, Supriya, Clegg, John R, Warren, Kaitlyn, Janes, Morgan, Park, Kyung Soo, Dunne, Michael, Ilelaboye, Bolu, Lu, Andrew, Darko, Solomina, Jaimes, Camilo, Mannix, Rebekah, Mitragotri, Samir

“…The choroid plexus (ChP) of the brain plays a central role in orchestrating the recruitment of peripheral leukocytes into the central nervous system (CNS)…”
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Immunotherapy against glioblastoma using backpack‐activated neutrophils by Fukuta, Tatsuya, Kumbhojkar, Ninad, Prakash, Supriya, Shaha, Suyog, Silva‐Candal, A. Da, Park, Kyung Soo, Mitragotri, Samir

“…Abstract Immune checkpoint inhibitors (ICIs) represent new therapeutic candidates against glioblastoma multiforme (GBM); however, their efficacy is clinically…”
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A biomimetic chip to assess subcutaneous bioavailability of monoclonal antibodies in humans by Chandran Suja, Vineeth, Qi, Qin M, Halloran, Kevin, Zhang, Jifeng, Shaha, Suyog, Prakash, Supriya, Kumbhojkar, Ninad, Deslandes, Antoine, Huille, Sylvain, Gokarn, Yatin R, Mitragotri, Samir

“…Abstract Subcutaneous (subQ) injection is a common route for delivering biotherapeutics, wherein pharmacokinetics is largely influenced by drug transport in a…”
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Backpack-mediated anti-inflammatory macrophage cell therapy for the treatment of traumatic brain injury by Kapate, Neha, Liao, Rick, Sodemann, Ryan Luke, Stinson, Tawny, Prakash, Supriya, Kumbhojkar, Ninad, Suja, Vineeth Chandran, Wang, Lily Li-Wen, Flanz, Mikayla, Rajeev, Rohan, Villafuerte, Dania, Shaha, Suyog, Janes, Morgan, Park, Kyung Soo, Dunne, Michael, Golemb, Bryan, Hone, Alexander, Adebowale, Kolade, Clegg, John, Slate, Andrea, McGuone, Declan, Costine-Bartell, Beth, Mitragotri, Samir

“…Traumatic brain injury (TBI) is a debilitating disease with no current therapies outside of acute clinical management. While acute, controlled inflammation is…”
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