Search Results - "Shah, Shivang"

Low Diagnostic Utility of Frequent Serial Tracheal Aspirate Cultures in the PICU by Feldman, Evin, Shah, Shivang S., Ahn, Danielle

“…To determine the diagnostic outcomes of serial tracheal aspirate cultures (TACs) in the PICU. A retrospective chart review of TAC utilization was performed…”
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The global role of G6PD in infection and immunity by Shah, Shivang S, Stone, Elizabeth F, Francis, Richard O, Karafin, Matthew S

“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in humans. G6PD is an essential enzyme in the pentose phosphate pathway…”
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Safety of ACEi and ARB in COVID‐19 management: A retrospective analysis by Kumar, Sabina, Nikravesh, Mastaneh, Chukwuemeka, Umeh, Randazzo, Michael, Flores, Peter, Choday, Prithi, Raja, Ajith, Aseri, Mahendra, Shivang, Shah, Chaudhuri, Sumanta, Barve, Pranav

“…Background & Aims Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV2)is a highly contagious virus that has infected 260 million individuals since…”
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Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection by Wong Fok Lung, Tania, Charytonowicz, Daniel, Beaumont, Kristin G., Shah, Shivang S., Sridhar, Shwetha H., Gorrie, Claire L., Mu, Andre, Hofstaedter, Casey E., Varisco, David, McConville, Thomas H., Drikic, Marija, Fowler, Brandon, Urso, Andreacarola, Shi, Wei, Fucich, Dario, Annavajhala, Medini K., Khan, Ibrahim N., Oussenko, Irina, Francoeur, Nancy, Smith, Melissa L., Stockwell, Brent R., Lewis, Ian A., Hachani, Abderrahman, Upadhyay Baskota, Swikrity, Uhlemann, Anne-Catrin, Ahn, Danielle, Ernst, Robert K., Howden, Benjamin P., Sebra, Robert, Prince, Alice

“…K. pneumoniae sequence type 258 (Kp ST258) is a major cause of healthcare-associated pneumonia. However, it remains unclear how it causes protracted courses of…”
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Multidimensional analysis of the host response reveals prognostic and pathogen-driven immune subtypes among adults with sepsis in Uganda by Cummings, Matthew J, Bakamutumaho, Barnabas, Price, Adam, Owor, Nicholas, Kayiwa, John, Namulondo, Joyce, Byaruhanga, Timothy, Muwanga, Moses, Nsereko, Christopher, Sameroff, Stephen, Tokarz, Rafal, Wong, Wai, Shah, Shivang S, Larsen, Michelle H, Lipkin, W Ian, Lutwama, Julius J, O'Donnell, Max R

“…The global burden of sepsis is concentrated in sub-Saharan Africa, where severe infections disproportionately affect young, HIV-infected adults and high-burden…”
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Hemozoin Promotes Lung Inflammation via Host Epithelial Activation by Shah, Shivang S, Fidock, David A, Prince, Alice S

“…Respiratory distress in severe malaria is associated with high mortality, but its pathogenesis remains unclear. The malaria pigment hemozoin (HZ) is abundant…”
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What about tocilizumab? A retrospective study from a NYC Hospital during the COVID-19 outbreak by Mehta, Monica, Purpura, Lawrence J, McConville, Thomas H, Neidell, Matthew J, Anderson, Michaela R, Bernstein, Elana J, Dietz, Donald E, Laracy, Justin, Gunaratne, Shauna H, Miller, Emily Happy, Cheng, Jennifer, Zucker, Jason, Shah, Shivang S, Chaudhuri, Shaoli, Gordillo, Christian A, Patel, Shreena R, Guo, Tai Wei, Karaaslan, Lara E, Reshef, Ran, Miko, Benjamin A, Bathon, Joan M, Pereira, Marcus R, Uhlemann, Anne-Catrin, Yin, Michael T, Sobieszczyk, Magdalena E

“…Tocilizumab, an interleukin-6 receptor blocker, has been used in the inflammatory phase of COVID-19, but its impact independent of corticosteroids remains…”
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HIV infection drives pro-inflammatory immunothrombotic pathway activation and organ dysfunction among adults with sepsis in Uganda by Cummings, Matthew J., Bakamutumaho, Barnabas, Price, Adam, Owor, Nicholas, Kayiwa, John, Namulondo, Joyce, Byaruhanga, Timothy, Jain, Komal, Postler, Thomas S., Muwanga, Moses, Nsereko, Christopher, Nayiga, Irene, Kyebambe, Stephen, Che, Xiaoyu, Sameroff, Stephen, Tokarz, Rafal, Shah, Shivang S., Larsen, Michelle H., Lipkin, W. Ian, Lutwama, Julius J., O’Donnell, Max R.

“…The global burden of sepsis is concentrated in high HIV-burden settings in sub-Saharan Africa (SSA). Despite this, little is known about the immunopathology of…”
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An acquired acyltransferase promotes Klebsiella pneumoniae ST258 respiratory infection by Ahn, Danielle, Bhushan, Gitanjali, McConville, Thomas H., Annavajhala, Medini K., Soni, Rajesh Kumar, Wong Fok Lung, Tania, Hofstaedter, Casey E., Shah, Shivang S., Chong, Alexander M., Castano, Victor G., Ernst, Robert K., Uhlemann, Anne-Catrin, Prince, Alice

“…Klebsiella pneumoniae ST258 is a human pathogen associated with poor outcomes worldwide. We identify a member of the acyltransferase superfamily 3 (atf3),…”
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Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children in Kenya: a case-control and a cohort study by Uyoga, Sophie, PhD, Ndila, Carolyne M, PhD, Macharia, Alex W, MSc, Nyutu, Gideon, MSc, Shah, Shivang, DPhil, Peshu, Norbert, MD, Clarke, Geraldine M, PhD, Kwiatkowski, Dominic P, Prof, Rockett, Kirk A, PhD, Williams, Thomas N, Prof

“…Summary Background The global prevalence of X-linked glucose-6-phosphate dehydrogenase (G6PD) deficiency is thought to be a result of selection by malaria, but…”
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Characterization of pulmonary vein reconnection post Cryoballoon ablation by Shah, Shivang, Xu, Wenjie, Adelstein, Evan, Voigt, Andrew, Saba, Samir, Jain, Sandeep

“…The Arctic Front Cryoballoon System is a technology in which substrate alterations in patients with atrial fibrillation (AF) recurrence have not been well…”
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Plasma free H2S levels are elevated in patients with cardiovascular disease by Peter, Elvis A, Shen, Xinggui, Shah, Shivang H, Pardue, Sibile, Glawe, John D, Zhang, Wayne W, Reddy, Pratap, Akkus, Nuri I, Varma, Jai, Kevil, Christopher G

“…Hydrogen sulfide (H2S) has been implicated in regulating cardiovascular pathophysiology in experimental models. However, there is a paucity of information…”
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Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria by Shah, Shivang S, Rockett, Kirk A, Jallow, Muminatou, Sisay-Joof, Fatou, Bojang, Kalifa A, Pinder, Margaret, Jeffreys, Anna, Craik, Rachel, Hubbart, Christina, Wellems, Thomas E, Kwiatkowski, Dominic P

“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency exhibits considerable allelic heterogeneity which manifests with variable biochemical and clinical…”
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Ventricular Tachycardia in an Elderly Male With Brugada Syndrome by Jaber, Mohammad, Basharat, Sohaib, Krishnan, Rajagopal, Shah, Shivang, Shu, Richard

“…We present a case of Brugada syndrome in a 74-year-old patient who presented with urine retention and incidentally found to have non–sustained ventricular…”
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Surgical and Medical Management of Purulent Bacterial Pericarditis With Pericardial Mass in a Young Child by Tarun, Samiksha, Makadia, Luv, Demirhan, Salih, Shah, Shivang S., Foca, Marc D., Bacha, Emile A., Thai, Lauren, Bansal, Neha, Pagan, Carlos A., Barry, Oliver M.

“…Purulent bacterial pericarditis is rare and associated with significant short- and long-term morbidity. We report a case of purulent bacterial pericarditis…”
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Benign Metastasizing Leiomyoma Causing Severe Tricuspid Regurgitation and Heart Failure by Jaber, Mohammad, Winner, Patricia Jean, Krishnan, Rajagopal, Shu, Richard, Khandelwal, Keerti M., Shah, Shivang

“…We present the case of a 51-year-old woman with severe tricuspid valve regurgitation due to aseptic tricuspid valve vegetation. She presented with bilateral…”
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A novel cytofluorometric assay for the detection and quantification of glucose-6-phosphate dehydrogenase deficiency by Shah, Shivang S., Diakite, Seidina A. S., Traore, Karim, Diakite, Mahamadou, Kwiatkowski, Dominic P., Rockett, Kirk A., Wellems, Thomas E., Fairhurst, Rick M.

“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked enzymopathy that affects hundreds of millions of people worldwide, conferring increased risk…”
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P53 regulation of osteoblast differentiation is mediated through specific microRNAs by Shah, Shivang, Pendleton, Elisha, Couture, Oliver, Broachwalla, Mustafa, Kusper, Teresa, Alt, Lauren A.C., Fay, Michael J., Chandar, Nalini

“…In order to understand the role of the p53 tumor suppressor gene in microRNA expression during osteoblast differentiation, we used a screen to identify…”
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Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma by Clark, Cheryl A, McEachern, Matthew D, Shah, Shivang H, Rong, Youhua, Rong, Xiaohua, Smelley, Christopher L, Caldito, Gloria C, Abreo, Fleurette W, Nathan, C O

“…Curcumin appears to be a safe, bioactive food compound that is a potential chemopreventive for patients at a high risk for head and neck squamous cell…”
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Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya by Shah, Shivang S, Macharia, Alex, Makale, Johnstone, Uyoga, Sophie, Kivinen, Katja, Craik, Rachel, Hubbart, Christina, Wellems, Thomas E, Rockett, Kirk A, Kwiatkowski, Dominic P, Williams, Thomas N

“…The relationship between glucose-6-phosphate dehydrogenase (G6PD) deficiency and clinical phenomena such as primaquine-sensitivity and protection from severe…”
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